LOCUS       sequence-46537-e         879 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 879)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 879)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MPP7
FEATURES             Location/Qualifiers
     source          1..879
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    19..118
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 accgggatca gctggatggc aataatgatt ttattttgac tgatagtgac ctgttcgttg
       61 caacaaattg ataagcaatg ctttcttata atgccaactt tgtacaagaa agttggcaat
      121 gaatgtaacc agctcactgg cacccaatgg gtctctgtct ctaatttgtc aaaagttgtt
      181 ttgagctcat tgaatgccac agtgaggtca tcatttatta taattttgtc aaaaagatga
      241 ccatattgac tttccattat ctgtgcagat ttaatcattt cttgaaaatc ttcttctgtg
      301 aagggttttg cagcaccttg gtcatctctg cttgaaataa tctttgcatt ttttcttgtt
      361 tctctcaaac gctctattga tggaggcttt ataaatatca catagggctt aaattctagt
      421 gtccttaaat gcttcactgt atgaggctga acatccaaca aacaaacttt gtttttagca
      481 aggacagacc gaactgagtc tatacttgtg ccgtagtagt tgtttttata ttctccatat
      541 tcaataaact tgttattttg tacatctgtc tcaaacaaat gcttggaaat gaaaatgtat
      601 tcaacaccat cactctcctg gcttcttctt gctctggtgg tatggggcac tgtcacgcca
      661 tagtgctggg tgtcactgat cagcagcttt cgtttcagtt cattcagccc tactcccacg
      721 ggaccaacca agacaacgag tctgtatttt tcattagttt gtcgccgata cggtgtcact
      781 tcttcgtatg tgggtacgtc agctgtgtcg tactgatcac tcttcttgca ttcatacatg
      841 gatttatttg ttttcttatc ttttctacta agacgacat
//
