LOCUS       sequence-46538-e         707 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 707)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-IRAK2
FEATURES             Location/Qualifiers
     source          1..707
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    16..115
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ttagatcgct ggatggcaat aatgatttta ttttgactga tagtgacctg ttcgttgcaa
       61 caaattgata agcaatgctt tcttataatg ccaactttgt acaagaaagt tggcaagggg
      121 ccaaagagct caatgctgtc cactttttcc tctttgtaga gcagaatatt ctccatcagt
      181 ttccttttgg cctcattgat ctcaatttgc cacgaagttt ctgtaacatc ctggggaggc
      241 tccaggccaa cacaggcctc agaggaggag tcagcctccc ttcccacgat gacccgcagc
      301 cttccttccc cattctctgt ggggagaagt ggggtggcag cccctgccca gggtgccaca
      361 ctcatggagg aggaggcatc aaggctggaa ttgtcaacgt cgtctgtttc ctctggggtg
      421 ttggaagaag agcctgtacc ctcagaaagc ccactccaag ggagcaacgt ctcccgacct
      481 cggagccgct cttccacagc agccacagag ccacacacct cctgcaggct ggtgttacgc
      541 ctccgcaggc acaggcaggc agccgtggcc agggcctcgg cgcagtcctc cggaagcctc
      601 cctgcgccct tctccaggta cttctggcag atctcctttg ccatcacgtt ctccacgccc
      661 gtcttcctgg agcagagcga ggcggtgctg cttggaatat cactgag
//
