LOCUS       sequence-46542-e         730 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 730)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 730)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PGK1
FEATURES             Location/Qualifiers
     source          1..730
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    14..113
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cttcagctgg atggcaataa tgattttatt ttgactgata gtgacctgtt cgttgcaaca
       61 aattgataag caatgctttc ttataatgcc aactttgtac aagaaagttg gcaaaatatt
      121 gctgagagca tccaccccag gaaggacttt accttccagg agctccaaac tggcaccacc
      181 cccagtgctc acatggctga ctttatcctc cgtgttccat ttggcacagc aagtggcagt
      241 gtctccacca cctatgatgg tgatgcagcc cctagaagtg gctttcacca cctcatccat
      301 gagagctttg gttccccggg caaaagcttc ccattcaaat acccccacag gaccattcca
      361 cacaatctgc ttagcccgag tgacagcctc agcatacttc ttgctgcttt caggaccaca
      421 gtccaagccc atccagccag caggtatgcc agaagccaca gtggcttggc cagtcttggc
      481 attctcatca aacttgtcag cagtgacaaa gtcaacaggc aaggtaatct tcacaccatt
      541 cttctcagct ttggacatta ggtctttgac aatcttggct ccctcttcat caaacagaga
      601 agtgccaatc tccatgttgt tgagcacctt aaggaaagta aaagccattc caccaccaat
      661 aatcatctca ttgactttgt ccagcatatt attgatgagc tggatcttgt ctgcaacttt
      721 agctccgccc
//
