LOCUS       sequence-46544-e         781 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 781)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-CDC2L6
FEATURES             Location/Qualifiers
     source          1..781
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 atatccagct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaagta
      121 ccggtgggcc tggtgagatg ggtggtactg tgagctctgc tgagacgagg aagagtagcc
      181 aagtgtgctc tgggactgag aggatccctg aacgctgctt tggtaattca ggcgagaact
      241 ggagtgctga taatccgagg gcatcacagg tccacctgag tttgcgcctg aaggccctag
      301 ccgtggcttc ttgtttggag gcacctggtt caggctggag tcctggctgt gctgcaaccc
      361 tgctccggtg cccccgaccc cggccccagc cccacctgcg gtcccgttgg tctgggtgct
      421 gttctgctgt ggtgggggcg cctgtggagg ggctgctgcc tgctgtggag gggctgtggg
      481 ctgctgatgc tggttctgct gctgttgctg attcttgtca cctttttctt caggatcatc
      541 ttcattaagg aattctcgtt tggggtatgg aatctggcag ccggcaaata catctaatgt
      601 tggcaaaggg tcctcctgaa aatagggatc ctgcagagct tgctccgagg taattctctt
      661 ggttggatcc atggtcagga gtttctgaag caagaggaac actttgctgt caggcttgac
      721 cttgtgtttc tccatgtact ttatgaggct actgttggca tacgttgttc ttctaaagtc
      781 t
//
