LOCUS       sequence-46687-e         763 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 763)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PAK3
FEATURES             Location/Qualifiers
     source          1..763
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 atatcaggct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaagcg
      121 gctgctgttc ttaattgctt cctttgcagc gataatcaga ggagtcaggc tggagagagg
      181 cttggctaat tttaaaaatg gatgctgcaa aagctccttg gcagatcctc gcctatccac
      241 atccatctca agacagcgat ttaaaaagtc acggaataca gctgacagtc tctcaggatt
      301 ctggagctct ggagttccat tagtggctat cagatacaat gccctgagtg gattttcatt
      361 aaggtaaggg ggttcacctt ccaccatttc aattgccata attccaagag accagatatc
      421 aactttcgga ccataagctt ttcgagtcac cacctcaggt gccatccaat atggggttcc
      481 caccatagtg cttcgtttac tttgctcagg agtgatctgg gcacagaacc caaagtcagt
      541 caatttaaca gagccatcca tcccgagaag aatattgtca ctctttatat ctctatggat
      601 cacctggttt gagtgcagga aatccaaagc ttgcaggcac tctctgcaga cagctgctat
      661 ctgtccttca tccatacagg tctctgtgac cacatcagtc agagagccac cagccaagta
      721 ttccatgact acccatagtt catcacccac caagtagcta tct
//
