LOCUS       sequence-46690-e         780 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 780)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 780)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-KSR
FEATURES             Location/Qualifiers
     source          1..780
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    20..119
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gggggattca gctgggatgg caataatgat tttattttga ctgatagtga cctgttcgtt
       61 gcaacaaatt gataagcaat gctttcttat aatgccaact ttgtacaaga aagttggcaa
      121 caactcagct gacttccaga agtgtccagg gtgggagagc cgccggttca gcttgggaag
      181 tttctccagc atgtccatca gcaggctgaa gctgggtctc tcctgcaggt cgaaagccca
      241 gcaggccgac aggatctcac tgacttcctt ccccaagctg acagaagtca ggacacgctt
      301 cattccttcc ccgcttccaa tctgccagat ggatgcctct gcagcctggt tcttcaaggg
      361 ccagtctctt gcttgcagct cataccaaac agtcccaaat gcatagacat cagcagcttt
      421 ggagaatggc agctgatcct cgtccttccc gggggtcatc tcgcgtacaa tctcaggggc
      481 cagatagcac agccagtcgt gggacagctt tagctggttc tcacgccgtc cctctcggac
      541 cacgcctgag atcccaaaca gcccgaagtc tgtgatgacc accttgccgt tgtcatagaa
      601 gacgttctta gatttgagat ctttgtgtac gatgcccttg gcatgaagat atcccatgcc
      661 cttgatgatc tcctgagcga tttgcctcgt cttgttgatg tccagagacg tcttggggtc
      721 cctcacaaac gagtgcaacg tccgcccctt gcagaagctg gtgataatgg ccagggtggg
//
