LOCUS       sequence-46692-e         819 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 819)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 819)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-RKHD3
FEATURES             Location/Qualifiers
     source          1..819
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    21..120
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ggggggatat cagctggatg gcaataatga ttttattttg actgatagtg acctgttcgt
       61 tgcaacaaat tgataagcaa tgctttctta taatgccaac tttgtacaag aaagttggca
      121 aagaaaagat gcggatggcc tgagtgaccg cggtgtggca gaccgggcac tcgggctcgc
      181 tcttctcaca gatgcgattg gcgcactcca tgcagaagag gttgtggcca cagggcacca
      241 gcgcggcaat cacttcgctc tcgaagcaca cggagcagtc gcggctgcct ttacgccgaa
      301 gcccggagga agaggatgaa gagctggagg aggagctgga cgaagaggag gagcccgacg
      361 tgtccgacgg ctgcaagcca ggcagctgtg cccccagccc gttggcataa gcggcgtagg
      421 ccaggcctcc tccacccggg tcgctgcgca cccggcgagc caggtggtgc tctcccgccc
      481 ccggggccat gtgcaagggt ggagacaggc gcgggcagct ggtgccaggg tgcagccggc
      541 ggtgcaccaa tagccccagg ttggcgttgg agggcgcact ggcgccaccc ccggggaaga
      601 ccacggagga ggaagaagca gacgaagatg cagaagaaga gcaggaagaa gataccggag
      661 ctgcaggtcc gcctcccggg gaccgctcga actgggccca gataagtggt gccccaggtg
      721 ggggagcggg agccgggtca aaagtgggct gcagctcggg gcagccgtcg ggggatggca
      781 ctgaggcttc tccccccgct gtgtaggtgt acccattgc
//
