LOCUS       sequence-46693-e         749 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 749)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MPP5
FEATURES             Location/Qualifiers
     source          1..749
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    23..122
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 atggggggaa tcagcgtgga tggcaataat gattttattt tgactgatag tgacctgttc
       61 gttgcaacaa attgataagc aatgctttct tataatgcca actttgtaca agaaagttgg
      121 caacctcagc caagtggatg gtacccactg aggttcagta tcaagtttgt taattaacct
      181 aagcaattcc tgataggctt tatcaagatc ggaattcaca attgccgtat caaagtagtg
      241 gccattgttc tgctccatct ctcttgtctt ctcaatgatt tctctcaact cttcaggctt
      301 tggattcttg ccttctttgg ccaataatgc ccgaagtctt tcttgtgaag ggggtgcaat
      361 gaagataata tatggtttca aatctgaatt ccggagagtc ttcaatgact gtgtacgaag
      421 acttaaaaga catattttgc cagagttgat cacttgccgt acagaatcta tgctagttcc
      481 atacaaattc ttctcaaatt caccatgctc aatgaacttt ccagctgcta tgtctgcctc
      541 gaatgcttgc cgcgaaacaa agtggtaatc tctaccggct acttcttggt ctcgcctact
      601 ccgggttgta tgaggaactg cagatgcaaa gcggtccttt tctttgttca tgagcctctg
      661 acgcaattca ttctggccac agttctgtgg accaatcaag atgataggtc tcttcctatt
      721 tgctggctga tgataaagtg acatttcct
//
