LOCUS       sequence-46696-e         803 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 803)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKR
FEATURES             Location/Qualifiers
     source          1..803
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gatttcaggc tgggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaac
      121 atgtgtgtcg ttcatttttc tctgggcttt tcttccacac agtcaaggtc cttagtattt
      181 cagatgtgtt aggtcgatcc tcaggtttct ttgagagtaa tttctgtaga agagttttct
      241 ttgatgtttc aaaagcagtg tcacatacat gaagaagttc agcaagaatt agccccaaag
      301 cgtagaggtc cacttccttt ccatagtctt gcgaagaaat ctgttctggg ctcatgtatc
      361 gcaaagttcc cttactcctt gttcgctttc catcattttt cagagatgtt acaagtccaa
      421 agtctccaat ctttacttgt tttgtatcta ctaagaatat attacttggc ttaagatctc
      481 tatgaattaa tttttttgaa tgtatataat ccaccccttt tgttatttgt tcaaagagtt
      541 ccaaagccaa aactttgtct agtttctcgc ctcttctttt ttcaatccat tgttccaagg
      601 tccctttatc acagaattcc atttggatga aaaggcactt agtctttgac cttgaactat
      661 ttttgctgtt ctcaggatca taatcactgc tctcaagaga atcatcactg gtctcaggat
      721 cataatcaaa tccatcccaa cagccattgt agtgaacaat atttacatga tcaagttttg
      781 ccaatgcttt tacttcacgc tcc
//
