LOCUS       sequence-46795-e         776 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 776)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP3K2
FEATURES             Location/Qualifiers
     source          1..776
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    21..120
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ggggggaatc agcctggatg gcaataatga ttttattttg actgatagtg acctgttcgt
       61 tgcaacaaat tgataagcaa tgctttctta taatgccaac tttgtacaag aaagttggca
      121 agtgataatg cacaaacatg tgccttaaga gttcatcagc tgaaggtctc agtttggcct
      181 ctacaaaaat ccgtttgagg aaatctcgag tatagtctga gacatgaggt ggcagctttg
      241 ggtttgttgg ctgagtggcg attttaaaga tggcagccat tgcttcaaat tcagcccaag
      301 gcggcttttc agttagcatt tctaccacag tacatgcaac actccagatg tctgcttttc
      361 ttccatagcc ttctccactg atgacttcag ggctcatcca gtatggtgtg cccgtgacag
      421 acttcattcc tgtccctgag agacagatgg tctgaagccg tttgctggcc ccaaaatctc
      481 ctagtttgac gttgcctgtt gaatctcgca ggatatttgc gcctttgata tctctatgga
      541 caatcatatt actgtgcaaa taatggacac cctccagaat ctgacgggtg tatttcctag
      601 tcacattctc agtaagagcg ccatatgctt ttaattggtc cttaattgaa ccccctggca
      661 tatattccat aaatatggaa agtgtttttt cctggggatc cctcaaacag ccataatact
      721 gaacaattcg ctcatgtagc aagtttttca gcaactgaat ttcacactca agtgca
//
