LOCUS       sequence-46797-e         649 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 649)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAST2
FEATURES             Location/Qualifiers
     source          1..649
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 atatcaggct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaagct
      121 ccaccacctc cgtgtgcacc aggccatgca caggttcccc attgacatgg gtgatgaggt
      181 caccttgacg aagccctgcc tcactggccg gacctccatc ctccacgtgc cacaccatat
      241 ggtgcacggt gtagacatcg gagtcaccca tgtagacgcg aatggcccgc agggtgaagc
      301 catacttctt ggagaagagt cccgggatga tgggttggac gactgagaat gtggggacat
      361 ggggctggcc aacggggagc aggtgtggtg ttccgaagga atgaggagtg agagggctgt
      421 ggctgaggcg gacttgatca ctttgttgac agggcgagca gtgcgcttct ctgttgagtc
      481 cccagagagc agccggtggc gggccctacg cacagccagg tcactgatgg ccttggctgt
      541 ggctccctca gccagctgtg aggtcccacg gcctcgggtc tccatagctg gactggaacc
      601 actgctccgg ccaacagctt cctcatccag ctttggccgc tgctcccct
//
