LOCUS       sequence-46806-e         731 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 731)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-CASK
FEATURES             Location/Qualifiers
     source          1..731
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 aaatcaagct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaaata
      121 gacccaggag acagggaccc actgtggggc tgtgcacacg agctcaacag cttcctccag
      181 atgtctgatt gtctcatcaa tttcattgtt gataattgtg agatcgaagt agtgtgcata
      241 tgttctctgt aagatgtcag actccttctg cagacgctga agagattcat cctcatttaa
      301 acctggagta atagttggtg cagcaatgaa aacaacaaaa ggagcaaact ctgcagttct
      361 caggaccttc agtgcctgag gctccacgtc cagtattgca atcagcccct gctcgtggat
      421 cttccggatg gtctccagtt ttgtcccata catcgcatcc tcgtggctgc cgtactccaa
      481 gtactcgtta ttagagatgt cttgcatcat ttggtcatga gatacaaagt aataattctt
      541 tccattttct tcgtctttct ttggaggtct ggttgtatgt ggaatagggt acgcaaaccg
      601 gtctgggtgc tttgtgatga gagtgttttt tatgtgtctt ctcccaacac catgtgcgcc
      661 taataagact agtgttttcc tcttgaatgc tggcagtttt actacttctt catatgtgac
      721 aagatctaat t
//
