LOCUS       sequence-46807-e         753 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 753)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PHKA1
FEATURES             Location/Qualifiers
     source          1..753
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    22..121
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 acgggggaat cagcctggat ggcaataatg attttatttt gactgatagt gacctgttcg
       61 ttgcaacaaa ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggc
      121 aattgcatgg cacagatgct gtgaggcagg aactcctgca cgtaggtggc ggctgccttg
      181 gagaggtagg tcatggtgcc aaacctgcca ctgggtgcac tgtcatacag aagagtacag
      241 atgccagatg cgggatcctt tgccaacatg gtatcatctg cgccaagggt tttctgttct
      301 tgaaggaaca agtcattggc aatatgcact attttttcca cagcaatgat gcttccgatg
      361 ctatgaattt caatatctgc cagcatggtg aggacaagga tggcttcaac cagcagctga
      421 cggtactctg gctgaggtac acgattcagg acagactcca catgaacaga gaatttaatc
      481 tcacctggag tcatctctct agtggtagag gaaggaagga caaacccttc aacagaaagt
      541 ccgtgacact tctgcaaaac tttccatact ttctgataaa atccaactgg aactctattc
      601 agtgccccat ccagccttct tcggcgttgc cattgacctt gacgactatc tttagatgac
      661 tgctgatcat atgcactagg aaaggaccca ctacttggag tcatagaggt tccaggtgac
      721 tgctttatct cactttttaa ctgcatgatc cca
//
