LOCUS       sequence-468764-         425 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Bacterial expression of human TTR mutants.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Leach BI, Ferguson JA, Morgan G, Sun X, Kroon G, Oyen D, Dyson HJ, 
            Wright PE
  TITLE     Conformational Dynamics of an Amyloidogenic Intermediate of 
            Transthyretin: Implications for Structural Remodeling and Amyloid 
            Formation.
  JOURNAL   J Mol Biol. 2024 Aug 15;436(16):168673. doi: 
            10.1016/j.jmb.2024.168673. Epub 2024 Jun 21.
  PUBMED    38909653
REFERENCE   2  (bases 1 to 425)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Mol 
            Biol."; date: "2024-08-15"; volume: "436(16):168673. doi"; pages: " 
            10.1016/j.jmb.2024.168673. Epub 2024 Jun 21"
COMMENT     Sequence Label: TTR C10S S85C F87E
FEATURES             Location/Qualifiers
     source          1..425
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     RBS             2..24
                     /note="efficient ribosome binding site from bacteriophage 
                     T7 gene 10 (Olins and Rangwala, 1989)"
ORIGIN
        1 ttttgtttaa ctttaagaag gagatataca tatgggtcct acgggcaccg gtgaatccaa
       61 gagtcctctg atggtcaaag ttctagatgc tgtccgaggc agtcctgcca tcaatgtggc
      121 cgtgcatgtg ttcagaaagg ctgctgatga cacctgggag ccatttgcct ctgggaaaac
      181 cagtgagtct ggagagctgc atgggctcac aactgaggag gaatttgtag aagggatata
      241 caaagtggaa atagacacca aatcttactg gaaggcactt ggcatctgcc cagagcatga
      301 gcatgcagag gtggtattca cagccaacga ctccggcccc cgccgctaca ccattgccgc
      361 cctgctgagc ccctactcct attccaccac ggctgtcgtc accaatccca aggaatgaga
      421 tccgg
//
