LOCUS       sequence-46877-e         742 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 742)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-TGFBR3
FEATURES             Location/Qualifiers
     source          1..742
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    16..115
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tttcaggctg ggatggcaat aatgatttta ttttgactga tagtgacctg ttcgttgcaa
       61 caaattgata agcaatgctt tcttataatg ccaactttgt acaagaaagt tggcaaggcc
      121 gtgctgctgc tggagcaagg cgtgctctgc gtgctgccga tgctgtgggc agcactgctg
      181 ttttccgagg ctggcgggga ggtggggact tgctgccttc ctgctgtctc ccctgtgtga
      241 gaatagatgt accacaaggc ccccgtcagg agtgctccga tcacaaaggc tgcaaacgca
      301 atgcccatca cggttagggt gtccagacca tggaaaattg gtggagaaat tggatttggt
      361 tccttcatgc ttggaccttt ttctttagat tctgcttcat ggtggatcac agcaaggggc
      421 ttagtgaacg tcttcttatt ctgcatcatg gcccagatta tcgaggcgtc cagcgaggtg
      481 caggcttcgt caggaggcac acacttaggc aacttctggg ggtgcttctc catcttcgta
      541 cacagcgtca gctcacactg tagaaagagc agtgaggtgt tgaagacagg cttgaagaca
      601 aagctgaatc gcttcttatc catgtcagct tgcgggatag gaaagtgcac tctcttggga
      661 ctgtagaatt tcacagattc atctttagga caaatattct caataatggt gtaatgagac
      721 atcctatcag ggttcgaata tg
//
