LOCUS       sequence-46878-e         927 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 927)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-NPR2
FEATURES             Location/Qualifiers
     source          1..927
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 aaatcaagct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaacag
      121 gagtccagga ggtcctttcc gctctcctaa gagccagtat gttcgcatct ttccttttcc
      181 cttcatttcc acatcccccc gaagctctag ctggaagcat cctagctcat ctagggcatc
      241 cttggtggta gaggagacat ggatcttcag cgcttgacca ttagactcca ttcgagaagc
      301 agtgttcact gtgtctccaa aaagacaata acggggcatc ttcaggccaa caaccccagc
      361 acagactggc cctttgagaa gaaacaggtt gggagagtct gggaaaggtg gagacttgta
      421 gacatcaaag ttgtcaatta tggcatcaaa ggaggtatac aggtcattaa gaagtgtcag
      481 tacctgcatg ggggtgctct ctgctgacga tgctgtgaag ccagacaatg tcactgaagt
      541 agatggtaac agtgtcaaag gcctcagcct gtacagtctc tccccgtgtt aactgctctg
      601 ccactgaatg gggtaggagt tggtagagga gagcttcagc cttgcgtgtt tcctccagat
      661 aggcctgtgt gcgtacctcc accatcttct ccgagttatt gggatactgt tccatgcgca
      721 gcaggaggtt gtccactatg cgggtgccaa cctgctagtt cagacgccga atgaagcgct
      781 taatctgtcc aaagtctggt cgctcatctg cggtctgagt ctaacatcga ctcgatcaca
      841 gaacatgctc ttccatgagg ttgggtccgg tcgatgcttg ccccggaaat agggaccgct
      901 gaccatttgc gtaccttctg gaacatc
//
