LOCUS       sequence-46880-e         760 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 760)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-HIPK2
FEATURES             Location/Qualifiers
     source          1..760
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    22..121
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 aggggggatt caggctggat ggcaataatg attttatttt gactgatagt gacctgttcg
       61 ttgcaacaaa ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggc
      121 aatatgtaag ggtactggtt gaccttggcg gggctcagtg ggtatccagt gtagacggtg
      181 gaggctggcg aggcgctgat gtaggtctgg tgggcaaatt gggctggata ctgactcggg
      241 tggatggtgg gcgagggcag gacccggggg cccatgctca cggggacctg gtggacgatg
      301 ctggctgggt aggcagtgtg ctgcacggtg tggcgcgcag agccttgcga ggccaccagg
      361 tgggccacgg tgccggtgga gcccagggcc gccggcgcag tgtaggtgta gaggtggggc
      421 tgggtgggga ggtgggcagc ggcagcggct gcagccagat gcgggtgcac agtgccgtgg
      481 ctggggctgt tgtgcgggaa ggagtacgga gcctgggcca tggtgggagt gatgtaggcc
      541 tgctgccttc ggtggctccc agtgcggtcc gtggtgatgt gctgctgagc ctggctgaga
      601 ttgagtggct gctgctgctg gaagtggggg cccggccgct gctgccggta ggtgatggct
      661 ccagatgagc tccctgaaga gtgaccgctg gtggaggtca cgttgctgga ggacttggac
      721 ttgtaggagg acgagtggtg actggtgttg actggcacca
//
