LOCUS       sequence-46881-e         759 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 759)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-CARD11
FEATURES             Location/Qualifiers
     source          1..759
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    20..119
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gggggattca gcttggatgg caataatgat tttattttga ctgatagtga cctgttcgtt
       61 gcaacaaatt gataagcaat gctttcttat aatgccaact ttgtacaaga aagttggcaa
      121 cagctggtcc tcgtccaccc agatggtctt gcgctgctcc tcgccgatct tgtccttgac
      181 aacgcggagc agctcctcta cgctgcccca catgtcaggt tccaccgtgg cgtacaggca
      241 cggcagggcc tccagctcct tctccttcag ccggcacacg cgcaggaact cctcctccgt
      301 ctcaggtcgg ggcagcagct ttctgaacct cttgatgttc ttctcacaca cccggatgaa
      361 gagcacgatg gggtagatgt tggacttgat caagtctctt gtgcagccga tcccagcctc
      421 cagcaggcag tgcttgttct tggcggccac agcttcaatg ttggcagggg cgatgcattc
      481 gaacgcgttg gggttcttct ctcgggagta gatgatggtc tccgtcttct gccttctgag
      541 gaactcatct cttgtgacga tatctgactt gcagatggtg aactccatgg cacctcccga
      601 gttgagcagc ctctgcacca gcgtcttggc cagcacggtg ggtgtgaaga gcacgggccg
      661 gcggcgctcg cagtagaagg cgcgtaccag gctgtagggg atgaggctga ggttcttgcc
      721 cagctcgctc tcagggtcca gctcttcctg cttctcagt
//
