LOCUS       sequence-46915-e         774 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 774)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-LRGUK
FEATURES             Location/Qualifiers
     source          1..774
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    20..119
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ggggatatca gcctggatgg caataatgat tttattttga ctgatagtga cctgttcgtt
       61 gcaacaaatt gataagcaat gctttcttat aatgccaact ttgtacaaga aagttggcaa
      121 cctgcggccc tgagggattg gagggagggt gggtttgacg ttggaacctg ggcgactgat
      181 gactgggacc gagtgttgtc tgtgttggtg agactctttt tcatgtgaaa atgattgtat
      241 aggtagtgct ttccgggtct cttcggtctc actgtcactg gctcctgatc ctaggtgtga
      301 agaaatgctc ccctccggag gctggaaagg caattctttt gaccacggac agaaccgaaa
      361 caatgaacat ttcatggaaa ccaaggaatc cttcccactc ttttcaggat atggtccaaa
      421 tggaggttta aaatagtctt cacaaagatc aaaacttttc cagagttctt ctaaagttgt
      481 ataatagtgt agaccactgg tgagaggtgc tggtactgga cccctttgaa ataggagtgt
      541 gtgatcaggg cgtatccttc ccattagagc ttgccgggct gcctcgtgct gtctgtgtat
      601 agaatctctt tccgctggtg tttttttggc tgaaagtttg gcccaaaatt taatgaggta
      661 gtttctgtct gtagaatgca ggaaatcacc catattcgaa gaaatatact ttgtaggatg
      721 cgcttcaggt ttcaggtggg atgtctttac atctgcagtt gtagccaaac tctt
//
