LOCUS       sequence-46917-e         728 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 728)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ERN1
FEATURES             Location/Qualifiers
     source          1..728
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 attgcaggct gggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaagag
      121 ggcgtctgga gtcactgggg gctggggctc tgggggctcg tggaagtagt agggctggaa
      181 gagtctctcg tggctgcaca gctccatggc ccggtaggtg tgtgcgagga ggtgggggaa
      241 gcgagacgtg aagtagcaca cgaagtcgtc ggggagggac cccagcgtct cccgcacctc
      301 tgcaggcagc tcccggtagt ggtgcttctt atttctcatg gctcggagga gatctctgac
      361 agaaccacct ttataggtcc tgaatttacg caggtctgtc tggaggggga cagtgatgtt
      421 ctcccgccag tccatcttca ccacggctct cccgcctctc tctaactgct tcacgatcgg
      481 gccatccagg gattcctttt ctattctgtc gctcacgtcc tggaagaact ggagctgctt
      541 ctctaggctc cagaagaacg ggtgtttgag cacgtgcttc gctgaggggc gtttctgagg
      601 atccatcgca atcatcttct ctatcaattc acgtgcaatg acgtcttcgt gcttctctgg
      661 gtgcaagcag tcaaggctgc aggcacccag gaggatgttg gcctgccgct gcagggactt
      721 gccaaaaa
//
