LOCUS       sequence-46921-e         814 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 814)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP3K15
FEATURES             Location/Qualifiers
     source          1..814
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cggggaaagg ctggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaag
      121 ccttgtcttt ggtttctgag gcctcctgag cccttctgta ctgggagacc gcactccaga
      181 gtctgcagag gagaccaccc cgtagtcgaa ggtatcttag atcttcctta gtgatctcat
      241 taagaatatc cgaaagtgta taaccctctt caacaatctt ttcaattgtc tttgcatcag
      301 ctccttgcag ccgcaaccag tctataagct ctttatctgt tctctgcccg taggggcctg
      361 ctgggttctc tgtaatacaa ttcgatttta attttaactg aaggtgatac aattcttgag
      421 ttttctgttc tagagtttgc cgcagaagat tctggtactc tctctctttt tcaactaggt
      481 gttccaaaag tctgttggtc tcctgtctga gctcacccag ctggaggctc aggtgctgct
      541 ggtggggctg ggcctcctgg ccaggtccgg tggctggggg atagccctct tccgcttcat
      601 ccatgtcctt atctacccct tcagtctcac aggtaggctc aaagtgggct cggagctctg
      661 ggatgagaat ggtgaccgcg gcctgcaccg ctcggcggat gatgttgtcc atcgcgaaca
      721 tccagtgggg cctaattaag tggttcctca aaattttatt tacgcatcct gaaatccgaa
      781 cagcaccagg tgaatctgac tgatggacga gctg
//
