LOCUS       sequence-46922-e         761 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 761)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKD1
FEATURES             Location/Qualifiers
     source          1..761
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cgtcctagag ctggatggga ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaga
      121 ggatgctgac acgctcaccg agggctttca tttctgtttc ttcagtctca ggagtgtcac
      181 tgtggctagc acttggattg atcaggtgtg tggggtactg cagcccctgc tcgcctgcat
      241 acttctccca cctcaggtca tcactttcat gggtgatgta gcgctccccg attttgcatt
      301 ccagctctcg caaatctaac caggtctgat agtcctgtag ccaagggtgg ctcaaggtct
      361 tatccacact gtagcgcttt ctcattttta cttgcagcaa attgttgata agatcaatgg
      421 cttcatgaga tatttccttc cagggatttg gtggatacat gaaagctgca ttctgaattt
      481 ggtcgtgtat gtcttcatct tcattaaatg ggaatgtgcc gcttaggctt acatagatga
      541 tgaccccaac agaccacatg tctagagagc gattgtagcc cttgttcctt aggacctcag
      601 gagccaggta agcgggggta cccaccactg acctccggaa agacttctct ccgatgatcc
      661 gggcaaaacc aaaatcacaa agtttcacct gaggaaaagg atcagctgag gctagcaaca
      721 cattttctgg tttgaggtca cagtgaacga tatttttaaa a
//
