LOCUS       sequence-46923-e         781 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 781)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-KSR2
FEATURES             Location/Qualifiers
     source          1..781
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cagagcacgc tggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaacag
      121 ctctgcagac ttccagaaat gtccagggtg agacaggcga cggtttcgct ttggcagttt
      181 ctccagcatg tccatgagct tggtgaaggt aggtctctct tcttgttcaa aggcccagca
      241 gaagagaaga atgtccgaga tttcttttcc catgccaatc tggctgaggt tgggtttcat
      301 gcctgtgccc atttgccaga ttattgcctc tgctggttgg gtcttgaaag gccattccct
      361 ggcgtggagt tcataccaga ttgtgccaag ggcaaagacg tcagagtgct tggagaaggg
      421 gagcttatcc tcctctgtgt cgggggacag ctggcggatg atctctggtg ccaggtggca
      481 tagccagcca ttctggatgc gcagtttgtc ctcccgcctg ccagcctgca gcaccccaga
      541 aatgctgaag agtccaaagt ccgtgatgac cactttgccg ttgtcataga agacgttctt
      601 tgacttgagg tccttgtgta ggattccctt ggcgtggagg tagcccatgc ccttcacaat
      661 ttcttgagca atctgcctgg ttttgttgac atccaaaacg attttggcat ccctcacaac
      721 ggaatagagc gtccgtccct tacagaggct ggtgatgatg ggccaggtga ggcgggctca
      781 t
//
