LOCUS       sequence-46924-e         845 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 845)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PI4KII
FEATURES             Location/Qualifiers
     source          1..845
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cactgatcag ctggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaacc
      121 accatgaaaa gaagggcttc cggctctgaa agctctgtgt gtaggactcg ctagaagacc
      181 gctggtggga acgggccgtc tcgacaatca caggtggcat ctggacgagg tgcaggggac
      241 tcttgttgtc tttcaaggcc tgggtcagat ttaagatctg gccccgcatg acagcaatct
      301 gcttatggaa ctggcccctg tcgaaaccag gatctttctt gaagagttca tataggtcct
      361 cttccaagtc cttgacgaag ttagggtccg atatctttgg aaggatcaga tctttgatct
      421 cctgagaaaa tgggactttc gcctggggca accaggccca gtaaaaagga tatgccctcc
      481 aggagtcagg atgcttcagt gggaaggcca gcccattgtc tatggcagcc accttgataa
      541 caggctcctt caccaccacc cagtctgtgt cccgagagct agaactatcc attggacagt
      601 catatttaat cagccagttg tcattgcctc gatcagtgtt gcggatgatg taatccagca
      661 ccaccaaccg ctcaaactgg agcagtagtt gccggttagt gttctcagga agaggttctg
      721 cttcaaaacg ccgcagccaa tagtctgcat ctttgtagcc ttcaacaaga gctggaatga
      781 accaaccctt tggtggtagc ccgatgcggt taaaccgctg tccaactttt ggcactttct
      841 ctagt
//
