LOCUS       sequence-46986-e         748 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 748)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PI4K2B
FEATURES             Location/Qualifiers
     source          1..748
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 atcagcacgc tggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaacca
      121 ggaggaaaaa aatggcttcc tgcaattgac agtctgggta aaggaattgc tcaggtggac
      181 aatccgaccc tgacttccac cttgactgcg ttccacaatc acacaaggta tctgtactag
      241 ctggaaagga ctcttcccgt ctctcaatgc ctgagtaagg tttaagatct gacccctcat
      301 cacagacatc tgactttcaa aagtggcttt gtcaaatcct ttgtcagtct taaaaagttc
      361 atagagatct tcacataaat cttgcacaaa gttcatgtca gaaatatatg gtagaatcaa
      421 atttcttatt tcttcagaaa agggaacttt tgcttgagga agccaagccc agtgaaatgg
      481 atatgctctc cattcatcag gatgtttaaa aggaaatgct agaccattat caattgcagc
      541 tattttaata aggaattctt catcatcaat ccattttgat tccttatggt caatttcctt
      601 ttcacatttc tgcttttcgt atctgactaa ccaattatca ttgcccctgt ctgtatttct
      661 gatgatgtaa tccaaaataa ctaatctttc aaattgtgac tgaaattgtt ttctaatatt
      721 ctcaggcaaa gggtcagctt caatttcc
//
