LOCUS       sequence-46990-e         865 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 865)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-DKFZp434B1231
FEATURES             Location/Qualifiers
     source          1..865
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    14..113
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ctcagcttgg atggctataa tgattttatt ttgactgata gtgacctgtt cgttgcaaca
       61 aattgataag caatgctttc ttataatgcc aactttgtac aagaaagttg gcaaggtgct
      121 gggttctatg acaatgaggg tggcagtgct gactgcctgg cccagcgtgt tctcagccac
      181 agccttgtac tccccgctgt ccttcgggga tacgctgggg atggtgaggg agcacacgcc
      241 cagcaggtca gtgctgtaca ccgcggggtt tccttccagg ctgcggtcat tcttgaacca
      301 ggtgacgtgg ggccggggcg agccctgcac ggcacagctc atgcagcact cgcagccctg
      361 gggcagcagg tgggaccgca ggcccaccag gaaccggggc ttctggctca ggtcgggctc
      421 ccggtagcac ggagccttca ctgtgaacct gtcgcgctgc cgggggatgc accagggctg
      481 gctggtgtcc gagggtttgc tggcccccag ctcattcttg gccaccaccc tgaagtggta
      541 ttcgtggccg gggaggatgc ccaggagggt gaagcggttg gtgtagatgc ggtcggctgc
      601 ctcgtgccag ggaccgtgcg ctgaggagcg tgtgaacacc gcgtagtgca gcgggacatc
      661 ctgggcctcg tcaggagagg gttcccactc ggccgtcacc gtcccacgca cgttctcctg
      721 cagtggatgg gcccagggcc tgcgggcatg ttcaaaggag acgggcacac gaactgtgtc
      781 cccgaccttg actgtcagca agtccttggt gctggagtcc acgaggaact tgggaaagac
      841 agtaacaggc atggcttgca ctaat
//
