LOCUS       sequence-47055-e         876 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 876)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-AURKA
FEATURES             Location/Qualifiers
     source          1..876
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     CDS             complement(416..427)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
ORIGIN
        1 gatatcaggc tgggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttgggtaag
      121 actgtttgct agctgattct ttgttttggc aatttgatgg ttttgatgaa tttgctgtga
      181 tccaggggtg ttcaagtact tctctgagca ttggcctctg gctgggatta tgcttcaaca
      241 gtcttgaaat gaggtccctg gctccctctg ttacaaagtc agggaatgtg aattcaaccc
      301 gtgatattct tttgtaggtc tcttggtatg tgtttgcctc aaaaggaggc ttcccaacta
      361 aaaattcata gcaaagaact ccaaggctcc agagatccac cttctcatca tgcatccgac
      421 cttcaatcat ttcagggggc aggtagtcca gggtgccaca gagagtggtc ctcctggaag
      481 atggagcatg tactgaccac ccaaaatctg caattttaag ctctccagct gatccaagaa
      541 gtaagttctc tggcttaatg tctctatgaa taactctctt cgaatgacag taagacaggg
      601 catttgccaa ttctgttata taagtagcag ttctctgctc atcaaacttt gaaagtttct
      661 gaagttctct ataaactgtt ccaagtggtg catattccag aattaggtag actctggtag
      721 catcatggaa ataaccatac agtctaagaa tattangatg ccgaangtgg gactgtattt
      781 ctacttctct tctgaactga tgctccactc cngctttctc cagctgagct ttaataacac
      841 ttttaagagc agaaataaac ttgctttgct tttctc
//
