LOCUS       sequence-47065-e         768 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 768)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK4CA
FEATURES             Location/Qualifiers
     source          1..768
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    11..110
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ctgaggatgg gcaataatga ttttattttg actgatagtg acctgttcgt tgcaacaaat
       61 tgataagcaa tgctttctta taatgccaac tttgtacaag aaagttggca agtaggggat
      121 gtcattctga tagtactgga tcatgtcgta ggtccggctc ctgttgctga ggaagcagct
      181 ctggatgacc ttcatgatga aatttgcagc ctcgcgctca gtcatgttgg ggctaaacct
      241 gtgcttcaag agcttgattg tctggccgcg aaaacagggc aggcccgtgt ccaacatgag
      301 agtgaccagg gagacgaccg cgtccatgta gggccgcaca gccaggtagc ctcggacaca
      361 catctccatg aaccacttga agggtgtggc ctccatcttg ccccccatga tcatcaccat
      421 ctcatccgtc agcttgatgt cgggttccca gccgagattg ccgcccggcg agctttcaaa
      481 catgaagcca aagtcgatgt ggatgatatg acccttcttg tccagcataa tgttgccgtt
      541 gtgtctgtcc ttgatctgca gcaggaacag caggaggctg taggcggcca tgcttcggat
      601 gaagttgtag cgggcctgct ggaaggccag agtggactca tccccgtact ggcgtgtgaa
      661 gtagtcgtac atgccgaagt ctgtctggcg gcccagctgg tcccgggagg tgcagtcggg
      721 gatgcactcg atcaccccgc acccaggggc agtggccacc acgcggta
//
