LOCUS       sequence-49864-e         727 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 727)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-RET
FEATURES             Location/Qualifiers
     source          1..727
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    12..111
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cagctggatg gcaaataatg attttatttt gactgatagt gacctgttcg ttgcaacaaa
       61 ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggg aatctagtaa
      121 atgcatggga aattctacca tagagtttgt tttcaatcca tgtggaaggg agggctcgag
      181 ggaggggggc attattacag tccaccagcg gtgtctcctc ctctgagagg ccgtcgtcat
      241 aaatcaggga gtcagatgga gtggacgccg caaggtccaa gtagtctctc ctcttaacca
      301 tcatcttctc caggtctttg ctgatgtccg caaacaccgg ccttttgtcc ggctcctgct
      361 tccagcattg cagcatcagg cagtacatct cctcgctgca gttgtctggc ctctccatcc
      421 ggtggccggt cttcagaagg ttgaagagcc gctcaggagg aatcccagga taggggtttc
      481 cccctagggt cacgatctcc cacagcagga caccaaaaga ccatacatca ctttgcgtgg
      541 tgtagatatg atcaaaaagg gattcaattg ccatccattt aactggaatc cgaccctggc
      601 tcctcttcac gtacgaatcc tcttcataaa catctcggga caagccgaaa tccgaaatct
      661 tcatcttccg cccctcagct accaggatgt ttctggctgc caagtcccga tgaacgagct
      721 tcatctc
//
