LOCUS       sequence-54277-e         889 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 889)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 889)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-NPR2
FEATURES             Location/Qualifiers
     source          1..889
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    12..111
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tcagctggat ggcaataatg attttatttt gactgatagt gacctgttcg ttgcaacaaa
       61 ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggc aacaggagtc
      121 caggaggtcc tttccgctct cctaagagcc agtatgttcg catctttcct tttcccttca
      181 tttccacatc cccccgaagc tctagctgga agcatcctag ctcatctagg gcatccttgg
      241 tggtagagga gacatggatc ttcagcgctt gaccattaga ctccattcga gaagcagtgt
      301 tcactgtgtc tccaaaaaga caataacggg gcatcttcag gccaacaacc ccagcacaga
      361 ctggcccttt gagaagaaac aggttgggag agtctgggaa aggtggagac ttgtagacat
      421 caaagttgtc aattatggca tcaaagcagg tatacaggtc attaagaagt gtcactacct
      481 gcatgggggt gctctctgct gacaatgctg tgaagccaac aatgtcactg aagtagatgg
      541 taacactgtc aaaggcctca gcctgtacag tctctccccg ttttaactgc tctgccactg
      601 aatggggtag gatttggtag agcagagctt cagccttgcg tttttcctcc agataggcct
      661 gtgtgcgttc ctccaccagc ttctccaagt tattggcata ctgttccatg cgcagcagga
      721 ggttgtccaa tatgctggtg ccaccctcct tgttaaagcg ccgaatgaag cccttaatct
      781 gtccaaagtc tggccgctca gctgggtcct gagcccaaca tcgctccatc agcaaaacta
      841 gctcttcatt cagttgggtc cggtcaatgc ttggccggaa atatggccg
//
