LOCUS       sequence-60510-e         749 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 749)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ALK
FEATURES             Location/Qualifiers
     source          1..749
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    74..98
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 aataatgatt ttattttgac tgatagtgac ctgttcgttg caacaaattg ataagcaatg
       61 ctttcttata atgccaactt tgtacaagaa agttgggggc ccaggctggt tcatgctatt
      121 cttgcttttc agaatggtat cctcgtaatg accagctcca ggggcagtag cggcttctaa
      181 gggcaagccc tgttgctggt agccgtaatt gacattccca caagggaagt gacgtagcct
      241 gaacagaggt acctccttca tattggcagt cagcgaagag ggctctagga gcagtgaggc
      301 ccccggaagt ctcccagttg caacgttagg tgggacagta cagcttccct ccagccccag
      361 gttacccctg tcgtgtggct ccttctttgc tataggatta ttctttttgg tgggtttctc
      421 tgtaaaccag gagccgtacg ttgggttcca caagctggtg ggcttgtttc tggatccgtg
      481 gaccttgtgc aactccgaag gagggttgga ctgagagaat gccatattca cgtgtccccc
      541 ttccacggcc ggccctctag ggactcgaac agagacctct gcagctgtgg gtttctttgc
      601 agccttgcca gaggaggtgg taggcagagg tggtggggca gctgggctgc gctcctcctc
      661 ccgttttgcc tgttgagaga ccaggagagg aggaaccccc tcagggtcct tgggcctcac
      721 aggcactttc tcttcctctt ccacaagtg
//
