LOCUS       sequence-75961-e         766 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses a TALE-TET1FL (full length TET1) fusion protein engineered
            to bind a site in the human KLF4 gene and demethylate CpGs adjacent 
            to the binding site.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai 
            SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson 
            MF, Joung JK
  TITLE     Targeted DNA demethylation and activation of endogenous genes using 
            programmable TALE-TET1 fusion proteins.
  JOURNAL   Nat Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726.
  PUBMED    24108092
REFERENCE   2  (bases 1 to 766)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726."
COMMENT     Sequence Label: SL357
FEATURES             Location/Qualifiers
     source          1..766
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ctatggtgga cttgaggaca ctcggttatt cgcaacagca acaggagaaa atcaagccta
       61 aggtcaggag caccgtcgcg caacaccacg aggcgcttgt ggggcatggc ttcactcatg
      121 cgcatattgt cgcgctttca cagcaccctg cggcgcttgg gacggtggct gtcaaatacc
      181 aagatatgat tgcggccctg cccgaagcca cgcacgaggc aattgtaggg gtcggtaaac
      241 agtggtcggg agcgcgagca cttgaggcgc tgctgactgt ggcgggtgag cttagggggc
      301 ctccgctcca gctcgacacc gggcagctgc tgaagatcgc gaagagaggg ggagtaacag
      361 cggtagaggc agtgcacgcc tggcgcaatg cgctcaccgg ggcccccttg aacctgaccc
      421 cagaccaggt agtcgcaatc gcgaacaata atgggggaaa gcaagccctg gaaaccgtgc
      481 aaaggttgtt gccggtcctt tgtcaagacc acggccttac accggagcaa gtcgtggcca
      541 ttgcaagcaa tgggggtggc aaacaggctc ttgagacggt tcagagactt ctcccagttc
      601 tctgtcaagc ccacgggctg actcccgatc aagttgtagc gattgcgaat aacaatggag
      661 ggaaacaagc attggagact gtccaacggc tccttcccgt gttgtgtcaa gcccacggtt
      721 tgacgcctgc acaagtggtc gccatcgcct cgaatggcgg cggtaa
//
