LOCUS       sequence-76801-e         830 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses a 3x Flag TALE-TET1CD (catalytic domain of TET1) fusion 
            protein engineered to bind a site in the human RHOXF2/2B homeobox 
            (RHOXF2) gene and demethylate CpGs adjacent to the binding site.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai 
            SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson 
            MF, Joung JK
  TITLE     Targeted DNA demethylation and activation of endogenous genes using 
            programmable TALE-TET1 fusion proteins.
  JOURNAL   Nat Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726.
  PUBMED    24108092
REFERENCE   2  (bases 1 to 830)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726."
COMMENT     Sequence Label: MLM3709
FEATURES             Location/Qualifiers
     source          1..830
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 tttggctgtt catggagtat gtactttaat ggctgtaagt ttggtagaag cccaagcccc
       61 agaagattta gaattgatcc aagctctccc ttacatgaaa aaaaccttga agataactta
      121 cagagtttgg ctacacgatt agctccaatt tataagcagt atgctccagt agcttaccaa
      181 aatcaggtgg aatatgaaaa tgttgcccga gaatgtcggc ttggcagcaa ggaaggtcga
      241 cccttctctg gggtcactgc ttgcctggac ttctgtgctc atccccacag ggacattcac
      301 aacatgaata atggaagcac tgtggtttgt accttaactc gagaagataa ccgctctttg
      361 ggtgttattc ctcaagatga gcagctccat gtgctacctc tttataagct ttcagacaca
      421 gatgagtttg gctccaagga aggaatggaa gccaagatca aatctggggc catcgaggtc
      481 ctggcacccc gccgcaaaaa aagaacgtgt ttcactcagc ctgttccccg ttctggaaag
      541 aagagggctg cgatgatgac agaggttctt gcacataaga taagggcagt ggaaaagaaa
      601 cctattcccc gaatcaagcg gaagaataac tcaacaacaa caaacaacag taagccttcg
      661 tcactgccaa ccttagggag taacactgag accgtgcaac ctgaagtaaa aagtgaaacc
      721 gaaccccatt ttatcttaaa aagttcagac aacactaaaa cttattcgct gatgccatcc
      781 gctcctcacc cagtgaaaga ggcatctcca ggcttctcct ggtccccgaa
//
