LOCUS       sequence-76964-e         862 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses a 3x Flag TALE-TET1CD (catalytic domain of TET1) fusion 
            protein engineered to bind a site in the human RHOXF2/2B homeobox 
            (RHOXF2) gene and demethylate CpGs adjacent to the binding site.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai 
            SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson 
            MF, Joung JK
  TITLE     Targeted DNA demethylation and activation of endogenous genes using 
            programmable TALE-TET1 fusion proteins.
  JOURNAL   Nat Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726.
  PUBMED    24108092
REFERENCE   2  (bases 1 to 862)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726."
COMMENT     Sequence Label: MLM3713
FEATURES             Location/Qualifiers
     source          1..862
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 cttttggctg ttcatggagt atgtacttta atggctgtaa gtttggtaga agcccaagcc
       61 ccagaagatt tagaattgat ccaagctctc ccttacatga aaaaaacctt gaagataact
      121 tacagagttt ggctacacga ttagctccaa tttataagca gtatgctcca gtagcttacc
      181 aaaatcaggt ggaatatgaa aatgttgccc gagaatgtcg gcttggcagc aaggaaggtc
      241 gacccttctc tggggtcact gcttgcctgg acttctgtgc tcatccccac agggacattc
      301 acaacatgaa taatggaagc actgtggttt gtaccttaac tcgagaagat aaccgctctt
      361 tgggtgttat tcctcaagat gagcagctcc atgtgctacc tctttataag ctttcagaca
      421 cagatgagtt tggctccaag gaaggaatgg aagccaagat caaatctggg gccatcgagg
      481 tcctggcacc ccgccgcaaa aaaagaacgt gtttcactca gcctgttccc cgttctggaa
      541 agaagagggc tgcgatgatg acagaggttc ttgcacataa gataagggca gtggaaaaga
      601 aacctattcc ccgaatcaag cggaagaata actcaacaac aacaaacaac agtaagcctt
      661 cgtcactgcc aaccttaggg agtaacactg agaccgtgca acctgaagta aaaagtgaaa
      721 ccgaacccca ttttatctta aaaagttcag acaacactaa aacttattcg ctgatgccat
      781 ccgctcctca cccagtgaaa gaggcatctc caggcttctc ctggtccccg aagactgctt
      841 cagccacacc agctccactg aa
//
