LOCUS       sequence-78008-e         890 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses a TALE-TET1CD (catalytic domain of TET1) fusion protein 
            engineered to bind a site in the human RHOXF2/2B homeobox (RHOXF2) 
            gene and demethylate CpGs adjacent to the binding site.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai 
            SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson 
            MF, Joung JK
  TITLE     Targeted DNA demethylation and activation of endogenous genes using 
            programmable TALE-TET1 fusion proteins.
  JOURNAL   Nat Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726.
  PUBMED    24108092
REFERENCE   2  (bases 1 to 890)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Biotechnol. 2013 Oct 9. doi: 10.1038/nbt.2726."
COMMENT     Sequence Label: SL539
FEATURES             Location/Qualifiers
     source          1..890
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ctgctgactg tggcgggtga gcttaggggg cctccgctcc agctcgacac cgggcagctg
       61 ctgaagatcg cgaagagagg gggagtaaca gcggtagagg cagtgcacgc ctggcgcaat
      121 gcgctcaccg gggccccctt gaacctgacc ccagaccagg tagtcgcaat cgcgtcgaac
      181 attgggggaa agcaagccct ggaaaccgtg caaaggttgt tgccggtcct ttgtcaagac
      241 cacggcctta caccggagca agtcgtggcc attgcaaata ataacggtgg caaacaggct
      301 cttgagacgg ttcagagact tctcccagtt ctctgtcaag cccacgggct gactcccgat
      361 caagttgtag cgattgcgtc caacggtgga gggaaacaag cattggagac tgtccaacgg
      421 ctccttcccg tgttgtgtca agcccacggt ttgacgcctg cacaagtggt cgccatcgcc
      481 tccaatattg gcggtaagca ggcgctggaa acagtacagc gcctgctgcc tgtactgtgc
      541 caggatcatg gactgacccc agaccaggta gtcgcaatcg cgaacaataa tgggggaaag
      601 caagccctgg aaaccgtgca aaggttgttg ccggtccttt gtcaagacca cggccttaca
      661 ccggagcaag tcgtggccat tgcaaataat aacggtggca aacaggctct tgagacggtt
      721 cagagacttc tcccagttct ctgtcaagcc cacgggctga ctcccgatca agttgtagcg
      781 attgcgaata acaatggagg gaaacaagca ttggagactg tccaacggct ccttcccgtg
      841 ttgtgtcaag cccacggttt gacgcctgca caagtggtcg ccatcgcctc
//
