LOCUS       sequence-82332-e       22249 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Targeting vector for homologous recombination in mouse ES cells; 
            Hipp11 locus.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 22249)
  AUTHORS   Tasic B, Hippenmeyer S, Wang C, Gamboa M, Zong H, Chen-Tsai Y, Luo L
  TITLE     Site-specific integrase-mediated transgenesis in mice via pronuclear
            injection.
  JOURNAL   Proc Natl Acad Sci U S A. 2011 May 10;108(19):7902-7. doi: 
            10.1073/pnas.1019507108. Epub 2011 Apr 4.
  PUBMED    21464299
REFERENCE   2  (bases 1 to 22249)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1073/pnas.1019507108"; journalName: "Proc Natl Acad Sci U S A"; 
            date: "2011-05-10- 10"; volume: "108"; issue: "19"; pages: "7902-7"
COMMENT     Sequence Label: 
            pBT311_pH11-U-attPx3-FRT5-pSV40-Neo-pA-pVasa-PhiC31o-pA-FRT5
FEATURES             Location/Qualifiers
     source          1..22249
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     promoter        5482..5586
                     /gene="bla"
                     /label=AmpR promoter
     promoter        5588..5945
                     /label=SV40 promoter
                     /note="SV40 enhancer and early promoter"
     enhancer        5588..5779
                     /label=SV40 enhancer
                     /note="enhancer for the SV40 early promoter (Herr, 1993)"
     primer_bind     complement(5611..5631)
                     /label=pBABE 3'
                     /note="SV40 enhancer, reverse primer for pBABE vectors"
     rep_origin      5796..5931
                     /label=SV40 ori
                     /note="SV40 origin of replication"
     CDS             5980..6774
                     /codon_start=1
                     /product="aminoglycoside phosphotransferase"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     CDS             5980..6774
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(6034..6053)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     6644..6663
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     primer_bind     complement(6962..6981)
                     /label=TK-pA-R
                     /note="Thymidine kinase polyA, reverse primer"
     polyA_signal    7006..7053
                     /label=HSV TK poly(A) signal
                     /note="herpes simplex virus thymidine kinase 
                     polyadenylation signal (Cole and Stacy, 1985)"
     RBS             7623..7631
                     /label=Shine-Dalgarno sequence
                     /note="full consensus sequence for ribosome-binding sites 
                     upstream of start codons in E. coli; complementary to a 
                     region in the 3' end of the 16S rRNA (Chen et al., 1994)"
     regulatory      12647..12656
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             12653..14467
                     /codon_start=1
                     /product="integrase from phage phi-C31"
                     /label=phage phi-C31 integrase
                     /translation="MDTYAGAYDRQSRERENSSAASPATQRSANEDKAADLQREVERDG
                     GRFRFVGHFSEAPGTSAFGTAERPEFERILNECRAGRLNMIIVYDVSRFSRLKVMDAIP
                     IVSELLALGVTIVSTQEGVFRQGNVMDLIHLIMRLDASHKESSLKSAKILDTKNLQREL
                     GGYVGGKAPYGFELVSETKEITRNGRMVNVVINKLAHSTTPLTGPFEFEPDVIRWWWRE
                     IKTHKHLPFKPGSQAAIHPGSITGLCKRMDADAVPTRGETIGKKTASSAWDPATVMRIL
                     RDPRIAGFAAEVIYKKKPDGTPTTKIEGYRIQRDPITLRPVELDCGPIIEPAEWYELQA
                     WLDGRGRGKGLSRGQAILSAMDKLYCECGAVMTSKRGEESIKDSYRCRRRKVVDPSAPG
                     QHEGTCNVSMAALDKFVAERIFNKIRHAEGDEETLALLWEAARRFGKLTEAPEKSGERA
                     NLVAERADALNALEELYEDRAAGAYDGPVGRKHFRKQQAALTLRQQGAEERLAELEAAE
                     APKLPLDQWFPEDADADPTGPKSWWGRASVDDKRVFVGLFVDKIVVTKSTTGRGQGTPI
                     EKRASITWAKPPTDDDEDDAQDGTEDVAA"
     CDS             14468..14488
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     polyA_signal    14521..14745
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     promoter        17804..18297
                     /label=PGK promoter
                     /note="mouse phosphoglycerate kinase 1 promoter"
     primer_bind     18230..18249
                     /label=mPGK-F
                     /note="Mouse PGK promoter, forward primer"
     CDS             18324..18893
                     /codon_start=1
                     /gene="Corynebacterium diphtheriae tox"
                     /product="diphteria toxin Fragment A"
                     /label=DTA
                     /translation="DDVVILLIFCMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDD
                     DWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELG
                     LSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEIN
                     FETRGKRGQDAMYEYMAQACAGNRVRR"
     intron          18970..19035
                     /label=small t intron
                     /note="SV40 (simian virus 40) small t antigen intron"
     polyA_signal    19109..19333
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     primer_bind     complement(19401..19421)
                     /label=T3
                     /note="T3 promoter, forward primer"
     promoter        complement(19401..19419)
                     /label=T3 promoter
                     /note="promoter for bacteriophage T3 RNA polymerase"
     primer_bind     complement(19440..19456)
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(19440..19456)
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     primer_bind     complement(19453..19475)
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     protein_bind    19464..19480
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(join(19488..19494,19495..19512,19513..19518))
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    19533..19554
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     primer_bind     complement(19671..19688)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(19842..20430)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(19922..19941)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(join(20601..21392,21393..21461))
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     21224..21243
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     promoter        complement(21462..21566)
                     /gene="bla"
                     /label=AmpR promoter
     rep_origin      complement(21592..22047)
                     /direction=LEFT
                     /label=f1 ori
                     /note="f1 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     primer_bind     complement(21729..21750)
                     /label=F1ori-F
                     /note="F1 origin, forward primer"
     primer_bind     21941..21960
                     /label=F1ori-R
                     /note="F1 origin, reverse primer"
     primer_bind     22174..22196
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     primer_bind     22188..22205
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     22189..22205
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     22215..22234
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        22215..22233
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 ccggccgctt aattaaggac tagaatagtt ctgtgcttca ggactccata tgaaaccctg
       61 cactaaatat cccaaaggct cttgctttag agaaactcca gaaggaattt tgttcatgag
      121 ttaggccctg tctcatcctt tataaaattc attataaaat tatataattt cattataaaa
      181 taaacaagaa caaaggatcc ttaatggtaa gttctagtaa ggtgtacgat aattgagttt
      241 tcatgtatgt aattttaaaa gaaaaataca aggaacaagt ggaatcatag gttctgaggt
      301 ctctgaaaca tctcttcccc attactaagg tatatttcca gccatgctct tccctcttct
      361 tagccctatt tcagggttga gaaacatgag aacacacaca ggcccatttt acagggtggc
      421 aaagatggat tgaagttctt gggacaatga ctacttgccc ctttgtgttc tcttgtagta
      481 gctataggtc agaacattag aattacctct gcccaagtaa acaaaatggg aactctttac
      541 cctgttgaag atggcttcac ctggtaaagc taggcttaag agcgagtgct gcatagccca
      601 gtggtcaagt gctccaaagc atatgtaaga ccctaggctt aattcccagt gtcctgaaaa
      661 gataaagcac tggcttagtg ttaggcaaag gcacttgagt gtgctgatct ctgcctcttc
      721 tctgcagctt tctccttcct tcacccctac ctcagtgatc cggaagatgt atgaaagcag
      781 agagaaaacc aaggaggaaa tggcacctgg aatggtggtt cctggtgatg gtaaagagga
      841 tactcagaag accagcgaag gtactgctgc ttacctgtgt cagaacatag gcatgagtga
      901 ctgcagtgtc agggagatgg gttagtgagc tcaaacttgc tcacttgaca ttgtggccag
      961 ccggggtaac gatgtgcttt agcttatgat tcttaccatc tttcaagttg aataacaaac
     1021 tcatttagca tattgatata gctcaattct ttttttaacg tatttgtgta tttgcctgtg
     1081 gtatgtctgc atcatgtgta tccagtgccc aaggaggcca gaagagggca tcagaacctc
     1141 tagaattgtg agccacatgt gggtgctggg aagaggtcct cttcaagagt atccaggtag
     1201 atagggggat agatgcaggg ttgttgttgt ttctgttaca ggttgtttgt tttatttgca
     1261 acaggatctt actgtgtagc tgtggctaac ctcaaactca cagagatcta ctggtctctg
     1321 cctcccaagt cttaggatta aaggtgcctc aactacatgc ctggcaactt gtgctttttg
     1381 ttttgtaaca ctatgtcaga ggtttttgag ttattccttt atgcaccggg aatgcagctc
     1441 aattgtacta agtagtagaa tacttgccag catgtacaag accatgggtt catgttcact
     1501 ccccaagaaa ggaaatgaca acatcaaaaa taattatttc agcaaagaat ttgaagacct
     1561 tggcatctat ggactggaga gatagatcag ggcactgttt gctcttccag aggacctggg
     1621 ttcaattgcc agcacccaca tgatagctca ccttttgtga cttcagccct aggtgaccta
     1681 gcaccctccc ctggcctctg tgagcactga actcgacagg cacacagaca tacatacagg
     1741 caaaacacca tccatataca tcataatata agaaaataag gttataaata aaatgtgggc
     1801 atctattcct agctcaaggc ctaactactc tatgaccata actcaactcc ggggcttatg
     1861 gagagtacca gctgtgcatc tgtctacatt taaagcaaat agatgacttt ccatgaaagc
     1921 atctaacatg gttaagagga aaaaagagcc ggcatggtgg cacacgcctt taatcccagc
     1981 acttgggaag cataggcagg tggatttctg agttcgaggc cagcctggtc tacaaagtga
     2041 gttccaggac agccagggct atacagagaa accatgtctt gaaaaaccaa aaaaaaaaaa
     2101 aaggaaaaaa gaattgtcag aatttttaaa agtaagattt gctgggttgt tgggaattga
     2161 aataaattga taaaggatat caaaatgtcc tgtaaatgaa tccttacaga gaacctgctg
     2221 tcatccaatc ccatacccaa tactgatcaa gactcttcta cgacaaatcc taagctttca
     2281 acattacagc ggtcttcatg ttccacccca ctctcccaga ccagccgtta taccaaagaa
     2341 caagattatc gacctaaaac agcaggaagg aaaacaccta ccttggcatc cccagtccca
     2401 ggaacacctt ttctccgccc tacccaccaa gttccccttg tccctcatgt tcctattgtt
     2461 cgacctgcac accagcttca cccaggatta gtccaaaggt tgatagccca aggggtacat
     2521 ccacagcatc ttccaagttt gctccaagct ggtgagtttc tgactgggtg tgggcattgg
     2581 ttattggtcg tagtataaaa attgctgcca ctaattaaat gttacattat actaagtatt
     2641 ccaaaaagat cttactagat ttaaattctt ctacctaagt agtgagtcca atccagtctc
     2701 acttccttag ctcacaaaaa gattaggaaa cctgccagac agtggtaata cacgccttta
     2761 atccctgcac tcaggaagca gaggcaggtg gatctctttg agttcaagga tagccagggt
     2821 acactaagga accctggctg tggcgttcat ttacaattgt gtctgtgtat gcatattcat
     2881 gtaccctggt acatgtatgg tggcaagtgt tcaccacatc cacctccttg taagtatcca
     2941 aatcaacaaa agtagtaaac tttgacattt ttaggaacat ctacaactca tgagtttctt
     3001 ctttctcccc atcaggtgtg cttcctcctg ggatagacat ggctccttta caggggctat
     3061 ctggcccact cctgggtcaa cccttgtacc ctttggtctc tgctgctagt caccctctcc
     3121 taaaccctcg tcctgggacc cctctgcatt tggcggtgat gcagcagcag ctacagcgct
     3181 caggtaaggt ttagaaatag gccaggttag ctgatcacac tggaaagttc tgagatttcc
     3241 aggagcaata gttatcactg cccctttgtt tcttaggtgt cactagaaaa acaggtgaag
     3301 tgaactgacc tgtgcagtct cagggattat tactactgca aggacagtcg gagccagcca
     3361 tgctctagct ctgtttttca cttcttataa gcctgagaat ttttgctgag atgtgaacat
     3421 gtcagccttg gtgggctttc ttacgttgca ttttcttacg ttgcattttg cactttagga
     3481 agcctttggt taaatcctct ggtagacttc ccatccccca aagtaacaaa ccattcaagc
     3541 aaagtaggtc agaaaatatt gtcaatactg agaacaggac ttgggagtga gtatccaagg
     3601 gtggtcttag tagacttgtg gggttctgtg ggtgaggtgt agagtagagc tactttgctg
     3661 cactgacact cttctctcca tagttctgca tcctccaggc tctagttccc aggcagcagc
     3721 tatcagcgtt cagactcctc agaatgtacc cagccggtcg ggcatgcccc acatgcactc
     3781 ccagctggag catcgtacca gccaaaggag cagctcccct gtgggccttg ccaaatggtt
     3841 tggctcagat gtgctacagc agcctctgcc ctccatgccc accaaagtca tcagtgtaga
     3901 tgaactggaa tatagacagt gaagagggca ggctggctca cccatacctg gacctgtggt
     3961 gacaccctgg tcatgactct cattccctct ttgtaatggg cttttacatt ggagcacact
     4021 atgtgaagat gtttagggga tccacatacc taccatgatc tacattatga cagaaggctg
     4081 ttaaatcgaa tgaacctaca tggttcaaat acaagggata caagattgtc agtcctggaa
     4141 gtctttcttt tataaaatat gtgaatgaag tgttggtgtc ttctagaggt gacacctaag
     4201 ggttctgaaa aaataaaatg tatagaccct tatgtacaga cctgtgtata aacttttgta
     4261 catacaaata gggtagcttt ttttgaactt atacatacag ctgtacataa agtaactatc
     4321 agttaggctt gtgtcaactg tttggatttt tttcacttga atatttggga ctttttcttt
     4381 tggtttatta aaagttacat atgccacgtg tgtgaacgat atggctggta ctgtgtttat
     4441 ttcttccatg aactaagaca gtctaaatga gttcctttca cgttttaatt ttaccttagg
     4501 acttctggaa tttcttctgc acataaagtt ctgatagcat tagtttaagc tggactaacc
     4561 ctgaaagtag cttgtggcaa gtatcaagga atcaatatta tactctacaa aatcaaagtt
     4621 tacagagaag tcatatagta atttttctga aatttactgg cacaatgtta atccagcctg
     4681 actccaacta attaatggtc acattaattt aagtctttcc cttgcctctg ctgcattagt
     4741 ttctctcaaa attgttaact tacaacttga agtctggtat tataaattga atgtaaagca
     4801 ttctgaaaga tactatactg attgcaggtt tttcagtcag gttcaagcta atttgaccag
     4861 tcattggatt aattatggat ctggggccat aaatgctatt ttaattccac tatagagatt
     4921 aaaataagcc attctccatt tcataatatt ctattggact ttgactgcag gggcctccaa
     4981 gtcttgacag tagattataa tccttcagct gcccactcta ctggaggagg acaaactggt
     5041 cacttttcag caaaacctgg ctgtggatca gggcagtctg gtacttccaa gctcattaga
     5101 tgcgtttaaa taggagatca tgcatccaga tctggtgata ggtggcaagt ggtattccgt
     5161 aaggatatcg ttttcgggag tagtgcccca actggggtaa cctttgagtt ctctcagttg
     5221 ggggcgtagg gtcgccgacg ttttcgggag tagtgcccca actggggtaa cctttgagtt
     5281 ctctcagttg ggggcgtagg gtcgccgacg ttttcgggag tagtgcccca actggggtaa
     5341 cctttgagtt ctctcagttg ggggcgtagg gtcgccgacg gatcctttgt cgacgaagtt
     5401 cctattccga agttcctatt cttcaaaagg tataggaact tcgctagcga ttattcaggt
     5461 ggcacttttc ggggaaatgt gcgcggaacc cctatttgtt tatttttcta aatacattca
     5521 aatatgtatc cgctcatgag acaataaccc tgataaatgc ttcaataata ttgaaaaagg
     5581 aagagtcctg aggcggaaag aaccagctgt ggaatgtgtg tcagttaggg tgtggaaagt
     5641 ccccaggctc cccagcaggc agaagtatgc aaagcatgca tctcaattag tcagcaacca
     5701 ggtgtggaaa gtccccaggc tccccagcag gcagaagtat gcaaagcatg catctcaatt
     5761 agtcagcaac catagtcccg cccctaactc cgcccatccc gcccctaact ccgcccagtt
     5821 ccgcccattc tccgccccat ggctgactaa ttttttttat ttatgcagag gccgaggccg
     5881 cctcggcctc tgagctattc cagaagtagt gaggaggctt ttttggaggc ctaggctttt
     5941 gcaaagatcg atcaagagac aggatgagga tcgtttcgca tgattgaaca agatggattg
     6001 cacgcaggtt ctccggccgc ttgggtggag aggctattcg gctatgactg ggcacaacag
     6061 acaatcggct gctctgatgc cgccgtgttc cggctgtcag cgcaggggcg cccggttctt
     6121 tttgtcaaga ccgacctgtc cggtgccctg aatgaactgc aagacgaggc agcgcggcta
     6181 tcgtggctgg ccacgacggg cgttccttgc gcagctgtgc tcgacgttgt cactgaagcg
     6241 ggaagggact ggctgctatt gggcgaagtg ccggggcagg atctcctgtc atctcacctt
     6301 gctcctgccg agaaagtatc catcatggct gatgcaatgc ggcggctgca tacgcttgat
     6361 ccggctacct gcccattcga ccaccaagcg aaacatcgca tcgagcgagc acgtactcgg
     6421 atggaagccg gtcttgtcga tcaggatgat ctggacgaag agcatcaggg gctcgcgcca
     6481 gccgaactgt tcgccaggct caaggcgagc atgcccgacg gcgaggatct cgtcgtgacc
     6541 catggcgatg cctgcttgcc gaatatcatg gtggaaaatg gccgcttttc tggattcatc
     6601 gactgtggcc ggctgggtgt ggcggaccgc tatcaggaca tagcgttggc tacccgtgat
     6661 attgctgaag agcttggcgg cgaatgggct gaccgcttcc tcgtgcttta cggtatcgcc
     6721 gctcccgatt cgcagcgcat cgccttctat cgccttcttg acgagttctt ctgagcggga
     6781 ctctggggtt cgaaatgacc gaccaagcga cgcccaacct gccatcacga gatttcgatt
     6841 ccaccgccgc cttctatgaa aggttgggct tcggaatcgt tttccgggac gccggctgga
     6901 tgatcctcca gcgcggggat ctcatgctgg agttcttcgc ccaccctagg gggaggctaa
     6961 ctgaaacacg gaaggagaca ataccggaag gaacccgcgc tatgacggca ataaaaagac
     7021 agaataaaac gcacggtgtt gggtcgtttg ttcataaacg cggggttcgg tcccagggct
     7081 ggcactctgt cgatacccca ccgagacccc attggggcca atacgcccgc gtttcttcct
     7141 tttccccacc ccacccccca agttcgggtg aaggcccagg gctcgcagcc aacgtcgggg
     7201 cggcaggccc tgccatagcc tcaggttact caggatcatc tctagcctgc aggtgtgcca
     7261 ccatgcctgg cccagtttct tgctttgtat tataaacttt atagctggta agactctgga
     7321 cccacacgtg tttgatttgt ctcttctctc ctgagacatt ttttcccagt aacatttcct
     7381 gaattttgta ttttattgtc tctgcatctg tgctgagaca taacatcttc tgtttcttct
     7441 atttgccatg aactgggagt taagtctaag aatttgatta aagctgaagt tgagtttgaa
     7501 atcaaacctc tacatgtagc gttttgtatt tcccactgtg atacatcaac cagcacatgg
     7561 ttcttggagg tctttgcttt gtggtataaa gttggcccag tgtgtttaaa tgttgtcctc
     7621 tttaaggagg tagctaggta agatcacacg ccggttacct acctccctac tgatgcacta
     7681 actggtgtgt ctagcctagc ctaaggccct agggtaccat gcatcccata atagattatg
     7741 tgaggcccaa cacatttgta gataacagca tcaggtcata gtgtcataag gttggacacc
     7801 cctggcagag tttcatgcac cacactatct tcaaaagagc taaagaagta aggtggaaaa
     7861 aacaaacatc atagtgttct gattttactg taacaggaaa agactcactg aaaagatgcc
     7921 aaggcccaga tttcccctcc cacaattcca agcttcatgg agaatgatac ctccactttg
     7981 gggatggaga agggattaaa tcctgaccac agacttgaag cagtaagaac ttatcaccgt
     8041 gatgtcagtt ctgggtggaa ccctatgcat cccgtggccc tgtacctgca gatgctgctg
     8101 ctggacctgt gatagatggc cagtactaca gttaggaatc tttccgacaa ctgcagcttt
     8161 tagaatggaa agcaaaactc cacctactgg atggcacaac atgaaagcaa ggactgtgcc
     8221 ttgcagctca gggccagcct tagtactagt ctctgaggga ccgttgctac caccggttcc
     8281 caacctgtag cagcacaact atcctggacc agggttcacg gatggagctc aagaccttga
     8341 catctgtcac agttatgctc tgcaccatga ggaagttgtc tcagtttgcc ttactgccac
     8401 agcaccggct gtgggctcag cattgtgaca ctcagagcca cagttctgga gcaggaacta
     8461 gggcaggtcc ctctggtgat tctttctaca gttcacgacc agaggctgtt ggctttggaa
     8521 ggcacctgga ggtctgtgca agccccggac agaggcttgt gtagatgaag gaccctttat
     8581 aaaaagctcc ctaattgagt cttgaaaaac tcacccgctg aggatttagg agaaacctaa
     8641 gcttggatcg cctcctaaca ctgccacagg taacctgaat tttggtgcca tatagtgtta
     8701 gaaactatag gctgagagag agaaaaaaaa aacattcttt tttcaatttc tgaaaacaaa
     8761 caaaaccaaa acaagccata ttatgaagac cggaataaat acctaatcct ttgtcctcga
     8821 atgacatcac acatcaataa gaaccaagga tgtttaagga actatgacct catctgacag
     8881 tataaatata aaatgccaga aaccgtcaag atagtaacca gtgtgggtgg atgctcatat
     8941 gtgtactgta ttagttactt tttcattgtt gtgataaaat accacgacta aagcctgact
     9001 tataggagaa ggaatttgtc ctgtgttttc agagtgataa gactccatca tggcagggac
     9061 gcatggaagc cagcaacagg tatgatgctg gggcagcaag ctgagagctc acatccacca
     9121 ctgaaggcac aaaacagcaa gtgtgagctg gaagtggtgt gaggctatat actagcaaag
     9181 gctgccctac tgatacgctg tctccaggag gactgcgttc cccaagcttc tctgatcatc
     9241 acaaccaact gaggactaaa tgttcaaata cctgggtcag tggggatcat ttctcattca
     9301 aacttccaca gataattaaa agcaaataaa tgaaccaggt ttaaggaaac ttactgaatt
     9361 ccaatagaaa atatagaaat aaatcaatac tttagtagat ataattgact gagacatggg
     9421 ggcaaatttt aaaaagttga aattcttgat aatgaaggta tactaaacaa aataaaattg
     9481 cattagggaa gcattgatgt tagagtaaat caagcagaag agagaatgag tgaattccaa
     9541 gataggccat ttgaaaatgc acagaagaga aaaagaatta agaggaagaa atgtactcat
     9601 ggtaaccttg gagcaacagt gaaagggtaa gtaggttagt ggggatatgg acgggacttg
     9661 agaacaccaa aggagttaat cgatgcaact acgttatgat caaccacagt caggttccag
     9721 gttctgcagt aaactgaatc tccagttttc acgctatgta gatccatctc catgaatctg
     9781 gcctggcctt gtgactttct ggtaactgat tagttgaaag ttgcaaatat aattgtttaa
     9841 cttcttatgc tagaattcaa gaagccttgc aactattacc ctggtccttt ggagcgatgt
     9901 ccctgacaag tgtgtccagt tgaaatgcag catccttaca gagtctgact gagattgtcc
     9961 aacaaccttc agagcctaag acagcctctt ggaaactatt caattgttct ggccatccca
    10021 gcccctagat gccagagtag agaagtcacc ttggatgtta aacaaactgg tattggaggt
    10081 tggggataaa ctcagtagta cagagcttgc ctggcacgct caagtaccta ggttcaaact
    10141 ctggcaatgc caaaaaagaa aaaagttgat agcaaactct cagatgattc aggttctagt
    10201 tagcgtttga atggaattgt atgagatggt ctcctgagcc ctctcaatcc ctgagagaga
    10261 atttttttgt aagtcaatat attatgcaat aatttgttat acagttgtac tggctaattt
    10321 gggtcaagct ggagttatca cagagaaagg agcttcagtt ggggaaatgc ctccatgaga
    10381 tccaactgta aggcattttc tcaattagtg atcaaggggg aaaggcccct tgtgggtagg
    10441 accatctctg ggctggtagt cttggttcta taagagagca ggctgagcaa gccaggtgag
    10501 gcaagccagt aaggaacatc cctccatggc ctctgtatca gctcctgctc ctgacctgct
    10561 tgagttccag tcctgacttc ctttggtgat gaacagcaat gtggaaagtg taagctgaat
    10621 aaaccctttc ctccccaatt tgcttagtgg tcatgatgtt ttgtccagga atagaaaccc
    10681 tgactaagac aatagtaata ggtaacaaga agagagctgt gaactcgtca tgtagttaag
    10741 ataagtgttt gctagatttc ctattgcata gttcctattt tctctttata tttggaaaaa
    10801 aattgtggta acataccttg gacacttatt gttgttctcc cccctgacct gcactcaatg
    10861 ctgaattctc agccaaactc tagtgatgtc ctccccattc aaaagcttca accttctagt
    10921 ctttatttaa aaaaatgtta ttattacatt tatttattct gtggtgtgtg tgtgtgagag
    10981 agaggatggg agcaggtgtg tgtgtgtgtg tgtcggtgtg tttgttaaat cagaacatga
    11041 gtgtgtgtgt aagacagaga cggggtgagt gtgtgtgtgt gtgtatggga gcaggtgtgt
    11101 gtgtgtgtgt gggtcagtgg ataagttgtg gaagtcagtt ctttccttcc cttactcgga
    11161 tctcagggat caaacgcaag tcctcaggtt gccaggtaca tgtcacctgt ctttgcttta
    11221 ttattattta gttctggctt ttgagcctaa gtgttatgtt acataggttg accttgaatt
    11281 agctatgcac tgagctcctg atcctcctgc ctatatcttc caagtaatgg ttacaggaat
    11341 gggccactgg acctagcaag tgaacctacc tggtcactcc aaaaatgcac agcaaagaat
    11401 atacgtttaa aaataggttc attttaggaa gtttgtccac attttaaatg acagttctgt
    11461 taaagtatac tgtgttttgt cctttgttaa atgtgacttt taaaagcaat tcaccttaat
    11521 agcctgggcg actacagtgc tcactgtata aatgctagtg tgtttttggt gctgaaacag
    11581 aaaggtggct ctagaaagct ggagttcctc atctttaagt tccagactga gatatctaga
    11641 acttcttcaa aaatccaggg aaaggaaagc gatggaagtg aaaataaaaa caagaacatg
    11701 ctttacatat atttgattgt gatccctttg gcgggtacta ggaaaaccac ggatggaatt
    11761 ttccttctag aaagaggtga ggagcaggca gaatgtgaac atctacttaa tgagctgaac
    11821 tggccggtgc cctcagaatt gtaaacaggt acaccacaaa tccaggcctt ggcagacaga
    11881 ccaagtcttc ctctcttcgg ttttcttttt acagactggc tttcttgaca acttcaagat
    11941 ggagtctcat ccttgccctt tttatggaga ggagaagcat tgcttctagt tggttttagt
    12001 agaggagtga agtgcatttc tcagatacaa agagagcact tgagacgttc ggactcagaa
    12061 tggccaagcc tggcactttg ggaggtcaag aggaggctgg aacggctggg agagaaagca
    12121 attagatgtt ccaccccttt ggtttttctc cagacagggt ttctctgtgt agccctgact
    12181 gtcctgaagt ttgctctgta gaccaggctg gcctccaccc agggatttgc ctgcctctgc
    12241 ctccccgagc cccagatttt tatttttatt tatatatata ttaacttttg aatgaacaca
    12301 atggaattga tgagcccttg gagagtgaaa cgggatgtcg tgcgtggcag ccccggggat
    12361 cagctcactc ccacaggcct cacaggccat ggagccaaga ggcctccctg cctcggcctc
    12421 ggcctcggcc tcaacaaagg tggagaacgc gcaggccgtc cgtccatggg gcgggaagtc
    12481 gcgcgccgcg gccgctgatt ggctggcggg cccggtcgcc tgatgctatt tgttgtcccc
    12541 gcgccaatga cgcagtcggc gtccggcgtc cacccgcacg tgcagccgtt taagccgcgt
    12601 cggccggccg cgaggagccc ggggagcctg gagcggagag ttaaccgcca ccatggatac
    12661 ctacgccgga gcctacgaca gacagagccg ggagagagag aacagcagcg ccgccagccc
    12721 cgccacccag agaagcgcca acgaggataa ggccgccgat ctgcagagag aggtggagag
    12781 ggacggcggc agattcagat ttgtgggcca cttcagcgag gcccctggca ccagcgcctt
    12841 cggcaccgcc gagagacccg agttcgagag aatcctgaac gagtgtaggg ccggcaggct
    12901 gaacatgatc atcgtgtacg acgtgtcccg gttcagcagg ctgaaggtga tggacgccat
    12961 ccctatcgtg tccgagctgc tggccctggg cgtgaccatc gtgtccaccc aggaaggcgt
    13021 ctttagacag ggcaacgtga tggacctgat ccacctgatc atgaggctgg acgccagcca
    13081 caaggagagc agcctgaaga gcgccaagat cctggacacc aagaacctgc agagggagct
    13141 gggcggctat gtgggcggca aggcccccta cggcttcgag ctggtgtccg agaccaagga
    13201 gatcacccgg aacggcagga tggtgaacgt ggtgatcaac aagctggccc acagcaccac
    13261 ccccctgacc ggccccttcg agtttgagcc cgacgtgatc aggtggtggt ggcgggagat
    13321 caagacccac aagcacctgc ctttcaagcc cggcagccag gccgccatcc accccggcag
    13381 catcaccggc ctgtgtaaga gaatggacgc cgacgccgtg cccaccagag gcgagaccat
    13441 cggcaagaaa accgccagca gcgcctggga ccccgccacc gtgatgagaa tcctgaggga
    13501 ccctaggatc gccggcttcg ccgccgaggt gatctacaag aagaagcccg acggcacccc
    13561 caccaccaag atcgagggct acagaatcca gagagacccc atcaccctga gacctgtgga
    13621 gctggactgt ggccctatca tcgagcctgc cgagtggtac gagctgcagg cctggctgga
    13681 cggcagaggc agaggcaagg gcctgagcag aggccaggcc atcctgagcg ccatggacaa
    13741 gctgtactgt gagtgtggcg ccgtgatgac cagcaagaga ggcgaggaga gcatcaagga
    13801 cagctaccgg tgccggagaa gaaaggtggt ggaccccagc gcccctggcc agcacgaggg
    13861 cacctgtaat gtgagcatgg ccgccctgga caagttcgtg gccgagcgga tcttcaacaa
    13921 gatccggcac gccgagggcg acgaggagac cctggccctg ctgtgggagg ccgccagaag
    13981 attcggcaag ctgaccgagg cccccgagaa gagcggcgag agggccaacc tggtggccga
    14041 gagagccgac gccctgaacg ccctggagga gctgtacgag gacagagccg ccggagccta
    14101 tgacggccct gtgggcagga agcacttcag aaagcagcag gccgccctga ccctgagaca
    14161 gcagggcgcc gaggaaagac tggccgagct ggaggccgcc gaggccccta agctgcccct
    14221 ggatcagtgg ttccccgagg atgccgacgc cgaccccacc ggccccaagt cctggtgggg
    14281 cagagccagc gtggacgaca agagggtgtt cgtgggcctg ttcgtggata agatcgtggt
    14341 gaccaagagc accaccggca ggggccaggg cacccccatc gagaagagag ccagcatcac
    14401 ctgggccaag cctcccaccg acgacgacga ggatgacgcc caggacggca ccgaggacgt
    14461 ggccgcccct aagaaaaagc ggaaagtgtg atagatctag agctcgctga tcagcctcga
    14521 ctgtgccttc tagttgccag ccatctgttg tttgcccctc ccccgtgcct tccttgaccc
    14581 tggaaggtgc cactcccact gtcctttcct aataaaatga ggaaattgca tcgcattgtc
    14641 tgagtaggtg tcattctatt ctggggggtg gggtggggca ggacagcaag ggggaggatt
    14701 gggaagacaa tagcaggcat gctggggatg cggtgggctc tatggacgtc ctagagaagt
    14761 tcctattccg aagttcctat tcttcaaaag gtataggaac ttcgcggccg cctagtaagg
    14821 ggcgcgccca tcatgctctc actgcctcct cagcttcaag aggaatctgg aaaaagcagt
    14881 cccactggtc aggaaaggaa cactagtgca cttatcctgg gtgtctgctg agccaacagt
    14941 ggtagtaagg taagggcagg atgtgtcaaa ctgccaatag agaactactt actcttcagg
    15001 ctgaagctga tggaacaggt aacaaaggca aacactaatc atgatcagca agatgaagca
    15061 gaaagggaac aaggggatat taaatgtgta tagacacgct agagagatgg ctcagcagtt
    15121 aagagaacta gctggtcttt cagaggtcct gagatcaatt ttagacaccc acatggtggc
    15181 tcatgaccat ctatctataa atggatctga ttttcatgtc tggcagtgta cagaagctaa
    15241 ctgaagaaag gtggaagacc cacaagagtt caagataagc cctatatagt gaagttcaag
    15301 gcaagctttt tctacctgaa acttagtctc aaaaaaaaat gaatacgtaa acagtcttcc
    15361 aggggataag aaccttacag aaaaagcaga aatgcctggg gcactggatt accgatgtaa
    15421 tcaaattcag tccttgaatt gaacacagga ttgcctagag caaggccagc cagagattca
    15481 tctcagaggg agaaaggtgt ctttggagca attttgtggt aatctagtat gtatcacata
    15541 agtttagacg catttgggac tggaaagatg tgaacaaagc accctatggc tcacatctgt
    15601 cattaactct agttccagtg cacctgacac cgtcttctgg cctctgcagt gaccaagcac
    15661 atgggtagta tgtagacata tacataagca aaacacacat cattaaaaag tgacatttcc
    15721 caaaggaagc tgaagaacca gttcttgaga agatagtaga aatcagaagg ggaaatagta
    15781 gacatacaga gggactgacc aggttgtgtc acctttatag gctaggctaa tggatgatcg
    15841 acactagcgc tctttgtgaa ggacacacaa atgagacata gtttatagga ctaaacacac
    15901 ttctaagcaa tttaatgaga cttaagaccc tgtctctagc aaatactctg gatgatattc
    15961 agctcaaggc tcttgtcaga catgtttcca ttttcaaggt gagctaactg gccaaaactg
    16021 ccaacaacct gtagtgaata gagaagatga gaaaatctgg attctcaaat gacctaatga
    16081 aagccactgg agcgccatat ggtttctgtg aaaatgcctt ttcaatcatt aacctcttaa
    16141 atgagtgtta gcatcctaac taatgagtgg tgcagaatag tgggtctgct tagcttaact
    16201 aaggccaaga aaacaaaaca ggaaattcat tccatgtcat gagactcata ctacgaggtt
    16261 cccttagacc tcaggagaaa aagtctttgg ctgtaagaac acacctcagt ggatgtggta
    16321 gactatgcct ttactctttt tttttttttt tttttttttt gggttttttc gagacagggt
    16381 ttctctgtgt agccttggct gtcctggaac tcactttgtt gaccaggctg gcctcgaact
    16441 cagagatccg cctgcctctg cctctcaagt gctagaatta aaagtgtgcg ccaccactcc
    16501 cagctatata gactatgcct ttaatcagga cacttgggag gcagggggat ctcaaattca
    16561 attccagaca gatgactgac aaacacacac atacaccatt cgtcttttct ttttttcttt
    16621 tttcttttga aaacaggttt ctctatgcag ccctggcttt cctagaattc aatctataga
    16681 cccagctggc ctcaaacaca gaacctcttg cctctgcctc ctcaacacta tgactaaagg
    16741 tgtgaaccac caccaccacc acccacctgg ccaaagaatg aattgagtga ataagtacga
    16801 gtgcaactct ccagcagcct gaggcaagaa agcttaacag ttgaacctga gaccctactt
    16861 cgtttgtgtt gtacatatct tctcataatg aactaggcag cctagtctct ctaccaaata
    16921 caccatgcac ttacacctcc tcaaaccaac tgcaacagct acacacattt ccatggcttg
    16981 cctgtaataa taaattcaca aacttcctct aagtaacttt tagtggaaat ctaccaggtt
    17041 atgcctattt gtgattgggt gcacagatga ctagatgaga tgtaatttgg gaagtgacat
    17101 gcaataggaa aaatgaatat ataacctata aatagaaaac accaaggcaa gcgtggtgac
    17161 tcacaccttt aattagcact tgggaggcag aagtcgcatc atctcttagg tcaaggccaa
    17221 tctagttcca gaccagcaag gacaacagaa accttgcctt gatataaaca ttttaaaact
    17281 ttaaaaatag agaagcccaa actctgctca ttggtaatct acccttcctt tctttagaca
    17341 ccttgagaag ctaggctaca tagctttggg tccttacgta cccccactca ctcagcctgc
    17401 agtcaatctc tgatagtgtt tcctgccata agctacacta ctgttttgct ccaaacctta
    17461 cttctagtac aaatccatgt gaggtcttcg tttcaatttg ggggggaaga ggccagaaca
    17521 cttgccgcag atcccaacaa cgggcagcac attcccagct agtgtatctg atacaaactc
    17581 tatcttcatt cagaaccatc aagtctaagc cccaagagca aaggtaaatt catgtatgtt
    17641 tggctggaga aagcatttca agtcaaggtg agccttgaac tcctaacact cttgcctcta
    17701 ccttccaaat gccaatatag gtatttgtca caccagcttc tcaaatcctg ttgggctagc
    17761 aactgggtcg acggtatcga taagcttgat atcgaattct accgggtagg ggaggcgctt
    17821 ttccaaggca gtctgagcat gcgcttagca gccccgctgg cacttggcgc tacacaagtg
    17881 gcctytggcc tcgcacacat tccacatcca ccggtaggcg ccaaccggct ccgttctttg
    17941 gtggcccctt cgcgccacct tctwctcctc ccctagtcag gaagttcccc cccgccccgc
    18001 agctcgcgtc gtsaggacgt gacaaatgga agtagcacgt ctcactagtc tcgtcagatg
    18061 gacagcaccg ctgagcaatg gaagcgggta ggcctttggg gcagcggcca atagcagctt
    18121 tgctccttcg ctttctgggc tcagaggctg ggaaggggtg ggtccggggg cgggctcagg
    18181 ggcgggctca ggggcggggc gggcgcccga aggtcctccg gaggcccggc attctgcacg
    18241 cttcaaaagc gcacgtctgc cgcgctgttc tcctcttcct catctccggg cctttcgacc
    18301 tgcaggtcct cgccatggat cctgatgatg ttgttattct tctaatcttt tgtatggaaa
    18361 acttttcttc gtaccacggg actaaacctg gttatgtaga ttccattcaa aaaggtatac
    18421 aaaagccaaa atctggtaca caaggaaatt atgacgatga ttggaaaggg ttttatagta
    18481 ccgacaataa atacgacgct gcgggatact ctgtagataa tgaaaacccg ctctctggaa
    18541 aagctggagg cgtggtcaaa gtgacgtatc caggactgac gaaggttctc gcactaaaag
    18601 tggataatgc cgaaactatt aagaaagagt taggtttaag tctcactgaa ccgttgatgg
    18661 agcaagtcgg aacggaagag tttatcaaaa ggttcggtga tggtgcttcg cgtgtagtgc
    18721 tcagccttcc cttcgctgag gggagttcta gcgttgaata tattaataac tgggaacagg
    18781 cgaaagcgtt aagcgtagaa cttgagatta attttgaaac ccgtggaaaa cgtggccaag
    18841 atgcgatgta tgagtatatg gctcaagcct gtgcaggaaa tcgtgtcagg cgatctcttt
    18901 gtgaaggaac cttacttctg tggtgtgaca taattggaca aactacctac agagatttaa
    18961 agctctaagg taaatataaa atttttaagt gtataatgtg ttaaactact gattctaatt
    19021 gtttgtgtat tttagattcc aacctatgga actgatgaat gggagcagtg gtggaatgca
    19081 gatcctagag ctcgctgatc agcctcgact gtgccttcta gttgccagcc atctgttgtt
    19141 tgcccctccc ccgtgccttc cttgaccctg gaaggtgcca ctcccactgt cctttcctaa
    19201 taaaatgagg aaattgcatc gcattgtctg agtaggtgtc attctattct ggggggtggg
    19261 gtggggcagg acagcaaggg ggaggattgg gaagacaata gcaggcatgc tggggatgcg
    19321 gtgggctcta tggcttctga ggcggaaaga accagctggg gctcgacctc gagggggggc
    19381 ccggtaccca gcttttgttc cctttagtga gggttaattg cgcgcttggc gtaatcatgg
    19441 tcatagctgt ttcctgtgtg aaattgttat ccgctcacaa ttccacacaa catacgagcc
    19501 ggaagcataa agtgtaaagc ctggggtgcc taatgagtga gctaactcac attaattgcg
    19561 ttgcgctcac tgcccgcttt ccagtcggga aacctgtcgt gccagctgca ttaatgaatc
    19621 ggccaacgcg cggggagagg cggtttgcgt attgggcgct cttccgcttc ctcgctcact
    19681 gactcgctgc gctcggtcgt tcggctgcgg cgagcggtat cagctcactc aaaggcggta
    19741 atacggttat ccacagaatc aggggataac gcaggaaaga acatgtgagc aaaaggccag
    19801 caaaaggcca ggaaccgtaa aaaggccgcg ttgctggcgt ttttccatag gctccgcccc
    19861 cctgacgagc atcacaaaaa tcgacgctca agtcagaggt ggcgaaaccc gacaggacta
    19921 taaagatacc aggcgtttcc ccctggaagc tccctcgtgc gctctcctgt tccgaccctg
    19981 ccgcttaccg gatacctgtc cgcctttctc ccttcgggaa gcgtggcgct ttctcatagc
    20041 tcacgctgta ggtatctcag ttcggtgtag gtcgttcgct ccaagctggg ctgtgtgcac
    20101 gaaccccccg ttcagcccga ccgctgcgcc ttatccggta actatcgtct tgagtccaac
    20161 ccggtaagac acgacttatc gccactggca gcagccactg gtaacaggat tagcagagcg
    20221 aggtatgtag gcggtgctac agagttcttg aagtggtggc ctaactacgg ctacactaga
    20281 aggacagtat ttggtatctg cgctctgctg aagccagtta ccttcggaaa aagagttggt
    20341 agctcttgat ccggcaaaca aaccaccgct ggtagcggtg gtttttttgt ttgcaagcag
    20401 cagattacgc gcagaaaaaa aggatctcaa gaagatcctt tgatcttttc tacggggtct
    20461 gacgctcagt ggaacgaaaa ctcacgttaa gggattttgg tcatgagatt atcaaaaagg
    20521 atcttcacct agatcctttt aaattaaaaa tgaagtttta aatcaatcta aagtatatat
    20581 gagtaaactt ggtctgacag ttaccaatgc ttaatcagtg aggcacctat ctcagcgatc
    20641 tgtctatttc gttcatccat agttgcctga ctccccgtcg tgtagataac tacgatacgg
    20701 gagggcttac catctggccc cagtgctgca atgataccgc gagacccacg ctcaccggct
    20761 ccagatttat cagcaataaa ccagccagcc ggaagggccg agcgcagaag tggtcctgca
    20821 actttatccg cctccatcca gtctattaat tgttgccggg aagctagagt aagtagttcg
    20881 ccagttaata gtttgcgcaa cgttgttgcc attgctacag gcatcgtggt gtcacgctcg
    20941 tcgtttggta tggcttcatt cagctccggt tcccaacgat caaggcgagt tacatgatcc
    21001 cccatgttgt gcaaaaaagc ggttagctcc ttcggtcctc cgatcgttgt cagaagtaag
    21061 ttggccgcag tgttatcact catggttatg gcagcactgc ataattctct tactgtcatg
    21121 ccatccgtaa gatgcttttc tgtgactggt gagtactcaa ccaagtcatt ctgagaatag
    21181 tgtatgcggc gaccgagttg ctcttgcccg gcgtcaatac gggataatac cgcgccacat
    21241 agcagaactt taaaagtgct catcattgga aaacgttctt cggggcgaaa actctcaagg
    21301 atcttaccgc tgttgagatc cagttcgatg taacccactc gtgcacccaa ctgatcttca
    21361 gcatctttta ctttcaccag cgtttctggg tgagcaaaaa caggaaggca aaatgccgca
    21421 aaaaagggaa taagggcgac acggaaatgt tgaatactca tactcttcct ttttcaatat
    21481 tattgaagca tttatcaggg ttattgtctc atgagcggat acatatttga atgtatttag
    21541 aaaaataaac aaataggggt tccgcgcaca tttccccgaa aagtgccacc taaattgtaa
    21601 gcgttaatat tttgttaaaa ttcgcgttaa atttttgtta aatcagctca ttttttaacc
    21661 aataggccga aatcggcaaa atcccttata aatcaaaaga atagaccgag atagggttga
    21721 gtgttgttcc agtttggaac aagagtccac tattaaagaa cgtggactcc aacgtcaaag
    21781 ggcgaaaaac cgtctatcag ggcgatggcc cactacgtga accatcaccc taatcaagtt
    21841 ttttggggtc gaggtgccgt aaagcactaa atcggaaccc taaagggagc ccccgattta
    21901 gagcttgacg gggaaagccg gcgaacgtgg cgagaaagga agggaagaaa gcgaaaggag
    21961 cgggcgctag ggcgctggca agtgtagcgg tcacgctgcg cgtaaccacc acacccgccg
    22021 cgcttaatgc gccgctacag ggcgcgtccc attcgccatt caggctgcgc aactgttggg
    22081 aagggcgatc ggtgcgggcc tcttcgctat tacgccagct ggcgaaaggg ggatgtgctg
    22141 caaggcgatt aagttgggta acgccagggt tttcccagtc acgacgttgt aaaacgacgg
    22201 ccagtgagcg cgcgtaatac gactcactat agggcgaatt ggagctcca
//
