LOCUS       sequence-82333-e       22288 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Targeting vector for homologous recombination in mouse ES cells; 
            Hipp11 locus.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 22288)
  AUTHORS   Tasic B, Hippenmeyer S, Wang C, Gamboa M, Zong H, Chen-Tsai Y, Luo L
  TITLE     Site-specific integrase-mediated transgenesis in mice via pronuclear
            injection.
  JOURNAL   Proc Natl Acad Sci U S A. 2011 May 10;108(19):7902-7. doi: 
            10.1073/pnas.1019507108. Epub 2011 Apr 4.
  PUBMED    21464299
REFERENCE   2  (bases 1 to 22288)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1073/pnas.1019507108"; journalName: "Proc Natl Acad Sci U S A"; 
            date: "2011-05-10- 10"; volume: "108"; issue: "19"; pages: "7902-7"
COMMENT     Sequence Label: 
            pBT312_pH11-U-attP-FRT5-pSV40-Neo-pA-pVasa-PhiC31o-pA-FRT5
FEATURES             Location/Qualifiers
     source          1..22288
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     protein_bind    5252..5351
                     /label=phage phi-C31 attP
                     /bound_moiety="phage phi-C31 integrase"
                     /note="attachment site of phage phi-C31"
     promoter        5521..5625
                     /gene="bla"
                     /label=AmpR promoter
     promoter        5627..5984
                     /label=SV40 promoter
                     /note="SV40 enhancer and early promoter"
     enhancer        5627..5818
                     /label=SV40 enhancer
                     /note="enhancer for the SV40 early promoter (Herr, 1993)"
     primer_bind     complement(5650..5670)
                     /label=pBABE 3'
                     /note="SV40 enhancer, reverse primer for pBABE vectors"
     rep_origin      5835..5970
                     /label=SV40 ori
                     /note="SV40 origin of replication"
     CDS             6019..6813
                     /codon_start=1
                     /product="aminoglycoside phosphotransferase"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     CDS             6019..6813
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKASMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(6073..6092)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     6683..6702
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     primer_bind     complement(7001..7020)
                     /label=TK-pA-R
                     /note="Thymidine kinase polyA, reverse primer"
     polyA_signal    7045..7092
                     /label=HSV TK poly(A) signal
                     /note="herpes simplex virus thymidine kinase 
                     polyadenylation signal (Cole and Stacy, 1985)"
     RBS             7662..7670
                     /label=Shine-Dalgarno sequence
                     /note="full consensus sequence for ribosome-binding sites 
                     upstream of start codons in E. coli; complementary to a 
                     region in the 3' end of the 16S rRNA (Chen et al., 1994)"
     regulatory      12686..12695
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             12692..14506
                     /codon_start=1
                     /product="integrase from phage phi-C31"
                     /label=phage phi-C31 integrase
                     /translation="MDTYAGAYDRQSRERENSSAASPATQRSANEDKAADLQREVERDG
                     GRFRFVGHFSEAPGTSAFGTAERPEFERILNECRAGRLNMIIVYDVSRFSRLKVMDAIP
                     IVSELLALGVTIVSTQEGVFRQGNVMDLIHLIMRLDASHKESSLKSAKILDTKNLQREL
                     GGYVGGKAPYGFELVSETKEITRNGRMVNVVINKLAHSTTPLTGPFEFEPDVIRWWWRE
                     IKTHKHLPFKPGSQAAIHPGSITGLCKRMDADAVPTRGETIGKKTASSAWDPATVMRIL
                     RDPRIAGFAAEVIYKKKPDGTPTTKIEGYRIQRDPITLRPVELDCGPIIEPAEWYELQA
                     WLDGRGRGKGLSRGQAILSAMDKLYCECGAVMTSKRGEESIKDSYRCRRRKVVDPSAPG
                     QHEGTCNVSMAALDKFVAERIFNKIRHAEGDEETLALLWEAARRFGKLTEAPEKSGERA
                     NLVAERADALNALEELYEDRAAGAYDGPVGRKHFRKQQAALTLRQQGAEERLAELEAAE
                     APKLPLDQWFPEDADADPTGPKSWWGRASVDDKRVFVGLFVDKIVVTKSTTGRGQGTPI
                     EKRASITWAKPPTDDDEDDAQDGTEDVAA"
     CDS             14507..14527
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     polyA_signal    14560..14784
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     promoter        17843..18336
                     /label=PGK promoter
                     /note="mouse phosphoglycerate kinase 1 promoter"
     primer_bind     18269..18288
                     /label=mPGK-F
                     /note="Mouse PGK promoter, forward primer"
     CDS             18363..18932
                     /codon_start=1
                     /gene="Corynebacterium diphtheriae tox"
                     /product="diphteria toxin Fragment A"
                     /label=DTA
                     /translation="DDVVILLIFCMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDD
                     DWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELG
                     LSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEIN
                     FETRGKRGQDAMYEYMAQACAGNRVRR"
     intron          19009..19074
                     /label=small t intron
                     /note="SV40 (simian virus 40) small t antigen intron"
     polyA_signal    19148..19372
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     primer_bind     complement(19440..19460)
                     /label=T3
                     /note="T3 promoter, forward primer"
     promoter        complement(19440..19458)
                     /label=T3 promoter
                     /note="promoter for bacteriophage T3 RNA polymerase"
     primer_bind     complement(19479..19495)
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(19479..19495)
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     primer_bind     complement(19492..19514)
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     protein_bind    19503..19519
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(join(19527..19533,19534..19551,19552..19557))
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    19572..19593
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     primer_bind     complement(19710..19727)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(19881..20469)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(19961..19980)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(join(20640..21431,21432..21500))
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     21263..21282
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     promoter        complement(21501..21605)
                     /gene="bla"
                     /label=AmpR promoter
     rep_origin      complement(21631..22086)
                     /direction=LEFT
                     /label=f1 ori
                     /note="f1 bacteriophage origin of replication; arrow 
                     indicates direction of (+) strand synthesis"
     primer_bind     complement(21768..21789)
                     /label=F1ori-F
                     /note="F1 origin, forward primer"
     primer_bind     21980..21999
                     /label=F1ori-R
                     /note="F1 origin, reverse primer"
     primer_bind     22213..22235
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     primer_bind     22227..22244
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     22228..22244
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     22254..22273
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        22254..22272
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
ORIGIN
        1 ccggccgctt aattaaggac tagaatagtt ctgtgcttca ggactccata tgaaaccctg
       61 cactaaatat cccaaaggct cttgctttag agaaactcca gaaggaattt tgttcatgag
      121 ttaggccctg tctcatcctt tataaaattc attataaaat tatataattt cattataaaa
      181 taaacaagaa caaaggatcc ttaatggtaa gttctagtaa ggtgtacgat aattgagttt
      241 tcatgtatgt aattttaaaa gaaaaataca aggaacaagt ggaatcatag gttctgaggt
      301 ctctgaaaca tctcttcccc attactaagg tatatttcca gccatgctct tccctcttct
      361 tagccctatt tcagggttga gaaacatgag aacacacaca ggcccatttt acagggtggc
      421 aaagatggat tgaagttctt gggacaatga ctacttgccc ctttgtgttc tcttgtagta
      481 gctataggtc agaacattag aattacctct gcccaagtaa acaaaatggg aactctttac
      541 cctgttgaag atggcttcac ctggtaaagc taggcttaag agcgagtgct gcatagccca
      601 gtggtcaagt gctccaaagc atatgtaaga ccctaggctt aattcccagt gtcctgaaaa
      661 gataaagcac tggcttagtg ttaggcaaag gcacttgagt gtgctgatct ctgcctcttc
      721 tctgcagctt tctccttcct tcacccctac ctcagtgatc cggaagatgt atgaaagcag
      781 agagaaaacc aaggaggaaa tggcacctgg aatggtggtt cctggtgatg gtaaagagga
      841 tactcagaag accagcgaag gtactgctgc ttacctgtgt cagaacatag gcatgagtga
      901 ctgcagtgtc agggagatgg gttagtgagc tcaaacttgc tcacttgaca ttgtggccag
      961 ccggggtaac gatgtgcttt agcttatgat tcttaccatc tttcaagttg aataacaaac
     1021 tcatttagca tattgatata gctcaattct ttttttaacg tatttgtgta tttgcctgtg
     1081 gtatgtctgc atcatgtgta tccagtgccc aaggaggcca gaagagggca tcagaacctc
     1141 tagaattgtg agccacatgt gggtgctggg aagaggtcct cttcaagagt atccaggtag
     1201 atagggggat agatgcaggg ttgttgttgt ttctgttaca ggttgtttgt tttatttgca
     1261 acaggatctt actgtgtagc tgtggctaac ctcaaactca cagagatcta ctggtctctg
     1321 cctcccaagt cttaggatta aaggtgcctc aactacatgc ctggcaactt gtgctttttg
     1381 ttttgtaaca ctatgtcaga ggtttttgag ttattccttt atgcaccggg aatgcagctc
     1441 aattgtacta agtagtagaa tacttgccag catgtacaag accatgggtt catgttcact
     1501 ccccaagaaa ggaaatgaca acatcaaaaa taattatttc agcaaagaat ttgaagacct
     1561 tggcatctat ggactggaga gatagatcag ggcactgttt gctcttccag aggacctggg
     1621 ttcaattgcc agcacccaca tgatagctca ccttttgtga cttcagccct aggtgaccta
     1681 gcaccctccc ctggcctctg tgagcactga actcgacagg cacacagaca tacatacagg
     1741 caaaacacca tccatataca tcataatata agaaaataag gttataaata aaatgtgggc
     1801 atctattcct agctcaaggc ctaactactc tatgaccata actcaactcc ggggcttatg
     1861 gagagtacca gctgtgcatc tgtctacatt taaagcaaat agatgacttt ccatgaaagc
     1921 atctaacatg gttaagagga aaaaagagcc ggcatggtgg cacacgcctt taatcccagc
     1981 acttgggaag cataggcagg tggatttctg agttcgaggc cagcctggtc tacaaagtga
     2041 gttccaggac agccagggct atacagagaa accatgtctt gaaaaaccaa aaaaaaaaaa
     2101 aaggaaaaaa gaattgtcag aatttttaaa agtaagattt gctgggttgt tgggaattga
     2161 aataaattga taaaggatat caaaatgtcc tgtaaatgaa tccttacaga gaacctgctg
     2221 tcatccaatc ccatacccaa tactgatcaa gactcttcta cgacaaatcc taagctttca
     2281 acattacagc ggtcttcatg ttccacccca ctctcccaga ccagccgtta taccaaagaa
     2341 caagattatc gacctaaaac agcaggaagg aaaacaccta ccttggcatc cccagtccca
     2401 ggaacacctt ttctccgccc tacccaccaa gttccccttg tccctcatgt tcctattgtt
     2461 cgacctgcac accagcttca cccaggatta gtccaaaggt tgatagccca aggggtacat
     2521 ccacagcatc ttccaagttt gctccaagct ggtgagtttc tgactgggtg tgggcattgg
     2581 ttattggtcg tagtataaaa attgctgcca ctaattaaat gttacattat actaagtatt
     2641 ccaaaaagat cttactagat ttaaattctt ctacctaagt agtgagtcca atccagtctc
     2701 acttccttag ctcacaaaaa gattaggaaa cctgccagac agtggtaata cacgccttta
     2761 atccctgcac tcaggaagca gaggcaggtg gatctctttg agttcaagga tagccagggt
     2821 acactaagga accctggctg tggcgttcat ttacaattgt gtctgtgtat gcatattcat
     2881 gtaccctggt acatgtatgg tggcaagtgt tcaccacatc cacctccttg taagtatcca
     2941 aatcaacaaa agtagtaaac tttgacattt ttaggaacat ctacaactca tgagtttctt
     3001 ctttctcccc atcaggtgtg cttcctcctg ggatagacat ggctccttta caggggctat
     3061 ctggcccact cctgggtcaa cccttgtacc ctttggtctc tgctgctagt caccctctcc
     3121 taaaccctcg tcctgggacc cctctgcatt tggcggtgat gcagcagcag ctacagcgct
     3181 caggtaaggt ttagaaatag gccaggttag ctgatcacac tggaaagttc tgagatttcc
     3241 aggagcaata gttatcactg cccctttgtt tcttaggtgt cactagaaaa acaggtgaag
     3301 tgaactgacc tgtgcagtct cagggattat tactactgca aggacagtcg gagccagcca
     3361 tgctctagct ctgtttttca cttcttataa gcctgagaat ttttgctgag atgtgaacat
     3421 gtcagccttg gtgggctttc ttacgttgca ttttcttacg ttgcattttg cactttagga
     3481 agcctttggt taaatcctct ggtagacttc ccatccccca aagtaacaaa ccattcaagc
     3541 aaagtaggtc agaaaatatt gtcaatactg agaacaggac ttgggagtga gtatccaagg
     3601 gtggtcttag tagacttgtg gggttctgtg ggtgaggtgt agagtagagc tactttgctg
     3661 cactgacact cttctctcca tagttctgca tcctccaggc tctagttccc aggcagcagc
     3721 tatcagcgtt cagactcctc agaatgtacc cagccggtcg ggcatgcccc acatgcactc
     3781 ccagctggag catcgtacca gccaaaggag cagctcccct gtgggccttg ccaaatggtt
     3841 tggctcagat gtgctacagc agcctctgcc ctccatgccc accaaagtca tcagtgtaga
     3901 tgaactggaa tatagacagt gaagagggca ggctggctca cccatacctg gacctgtggt
     3961 gacaccctgg tcatgactct cattccctct ttgtaatggg cttttacatt ggagcacact
     4021 atgtgaagat gtttagggga tccacatacc taccatgatc tacattatga cagaaggctg
     4081 ttaaatcgaa tgaacctaca tggttcaaat acaagggata caagattgtc agtcctggaa
     4141 gtctttcttt tataaaatat gtgaatgaag tgttggtgtc ttctagaggt gacacctaag
     4201 ggttctgaaa aaataaaatg tatagaccct tatgtacaga cctgtgtata aacttttgta
     4261 catacaaata gggtagcttt ttttgaactt atacatacag ctgtacataa agtaactatc
     4321 agttaggctt gtgtcaactg tttggatttt tttcacttga atatttggga ctttttcttt
     4381 tggtttatta aaagttacat atgccacgtg tgtgaacgat atggctggta ctgtgtttat
     4441 ttcttccatg aactaagaca gtctaaatga gttcctttca cgttttaatt ttaccttagg
     4501 acttctggaa tttcttctgc acataaagtt ctgatagcat tagtttaagc tggactaacc
     4561 ctgaaagtag cttgtggcaa gtatcaagga atcaatatta tactctacaa aatcaaagtt
     4621 tacagagaag tcatatagta atttttctga aatttactgg cacaatgtta atccagcctg
     4681 actccaacta attaatggtc acattaattt aagtctttcc cttgcctctg ctgcattagt
     4741 ttctctcaaa attgttaact tacaacttga agtctggtat tataaattga atgtaaagca
     4801 ttctgaaaga tactatactg attgcaggtt tttcagtcag gttcaagcta atttgaccag
     4861 tcattggatt aattatggat ctggggccat aaatgctatt ttaattccac tatagagatt
     4921 aaaataagcc attctccatt tcataatatt ctattggact ttgactgcag gggcctccaa
     4981 gtcttgacag tagattataa tccttcagct gcccactcta ctggaggagg acaaactggt
     5041 cacttttcag caaaacctgg ctgtggatca gggcagtctg gtacttccaa gctcattaga
     5101 tgcgtttaaa taggagatca tgcatccaga tctggtgata ggtggcaagt ggtattccgt
     5161 aaggatatcg gatcttttct cgactagtac tgacggacac accgaagccc cggcggcaac
     5221 cctcagcgga tgccccgggg cttcacgttt tcccaggtca gaagcggttt tcgggagtag
     5281 tgccccaact ggggtaacct ttgagttctc tcagttgggg gcgtagggtc gccgacatga
     5341 cacaaggggt tgtgaccggg gtggacacgt acgcgggtgc ttacgaccgt cagtcgcgcg
     5401 agcgcgacta gtcgagaagg atcctttgtc gacgaagttc ctattccgaa gttcctattc
     5461 ttcaaaaggt ataggaactt cgctagcgat tattcaggtg gcacttttcg gggaaatgtg
     5521 cgcggaaccc ctatttgttt atttttctaa atacattcaa atatgtatcc gctcatgaga
     5581 caataaccct gataaatgct tcaataatat tgaaaaagga agagtcctga ggcggaaaga
     5641 accagctgtg gaatgtgtgt cagttagggt gtggaaagtc cccaggctcc ccagcaggca
     5701 gaagtatgca aagcatgcat ctcaattagt cagcaaccag gtgtggaaag tccccaggct
     5761 ccccagcagg cagaagtatg caaagcatgc atctcaatta gtcagcaacc atagtcccgc
     5821 ccctaactcc gcccatcccg cccctaactc cgcccagttc cgcccattct ccgccccatg
     5881 gctgactaat tttttttatt tatgcagagg ccgaggccgc ctcggcctct gagctattcc
     5941 agaagtagtg aggaggcttt tttggaggcc taggcttttg caaagatcga tcaagagaca
     6001 ggatgaggat cgtttcgcat gattgaacaa gatggattgc acgcaggttc tccggccgct
     6061 tgggtggaga ggctattcgg ctatgactgg gcacaacaga caatcggctg ctctgatgcc
     6121 gccgtgttcc ggctgtcagc gcaggggcgc ccggttcttt ttgtcaagac cgacctgtcc
     6181 ggtgccctga atgaactgca agacgaggca gcgcggctat cgtggctggc cacgacgggc
     6241 gttccttgcg cagctgtgct cgacgttgtc actgaagcgg gaagggactg gctgctattg
     6301 ggcgaagtgc cggggcagga tctcctgtca tctcaccttg ctcctgccga gaaagtatcc
     6361 atcatggctg atgcaatgcg gcggctgcat acgcttgatc cggctacctg cccattcgac
     6421 caccaagcga aacatcgcat cgagcgagca cgtactcgga tggaagccgg tcttgtcgat
     6481 caggatgatc tggacgaaga gcatcagggg ctcgcgccag ccgaactgtt cgccaggctc
     6541 aaggcgagca tgcccgacgg cgaggatctc gtcgtgaccc atggcgatgc ctgcttgccg
     6601 aatatcatgg tggaaaatgg ccgcttttct ggattcatcg actgtggccg gctgggtgtg
     6661 gcggaccgct atcaggacat agcgttggct acccgtgata ttgctgaaga gcttggcggc
     6721 gaatgggctg accgcttcct cgtgctttac ggtatcgccg ctcccgattc gcagcgcatc
     6781 gccttctatc gccttcttga cgagttcttc tgagcgggac tctggggttc gaaatgaccg
     6841 accaagcgac gcccaacctg ccatcacgag atttcgattc caccgccgcc ttctatgaaa
     6901 ggttgggctt cggaatcgtt ttccgggacg ccggctggat gatcctccag cgcggggatc
     6961 tcatgctgga gttcttcgcc caccctaggg ggaggctaac tgaaacacgg aaggagacaa
     7021 taccggaagg aacccgcgct atgacggcaa taaaaagaca gaataaaacg cacggtgttg
     7081 ggtcgtttgt tcataaacgc ggggttcggt cccagggctg gcactctgtc gataccccac
     7141 cgagacccca ttggggccaa tacgcccgcg tttcttcctt ttccccaccc caccccccaa
     7201 gttcgggtga aggcccaggg ctcgcagcca acgtcggggc ggcaggccct gccatagcct
     7261 caggttactc aggatcatct ctagcctgca ggtgtgccac catgcctggc ccagtttctt
     7321 gctttgtatt ataaacttta tagctggtaa gactctggac ccacacgtgt ttgatttgtc
     7381 tcttctctcc tgagacattt tttcccagta acatttcctg aattttgtat tttattgtct
     7441 ctgcatctgt gctgagacat aacatcttct gtttcttcta tttgccatga actgggagtt
     7501 aagtctaaga atttgattaa agctgaagtt gagtttgaaa tcaaacctct acatgtagcg
     7561 ttttgtattt cccactgtga tacatcaacc agcacatggt tcttggaggt ctttgctttg
     7621 tggtataaag ttggcccagt gtgtttaaat gttgtcctct ttaaggaggt agctaggtaa
     7681 gatcacacgc cggttaccta cctccctact gatgcactaa ctggtgtgtc tagcctagcc
     7741 taaggcccta gggtaccatg catcccataa tagattatgt gaggcccaac acatttgtag
     7801 ataacagcat caggtcatag tgtcataagg ttggacaccc ctggcagagt ttcatgcacc
     7861 acactatctt caaaagagct aaagaagtaa ggtggaaaaa acaaacatca tagtgttctg
     7921 attttactgt aacaggaaaa gactcactga aaagatgcca aggcccagat ttcccctccc
     7981 acaattccaa gcttcatgga gaatgatacc tccactttgg ggatggagaa gggattaaat
     8041 cctgaccaca gacttgaagc agtaagaact tatcaccgtg atgtcagttc tgggtggaac
     8101 cctatgcatc ccgtggccct gtacctgcag atgctgctgc tggacctgtg atagatggcc
     8161 agtactacag ttaggaatct ttccgacaac tgcagctttt agaatggaaa gcaaaactcc
     8221 acctactgga tggcacaaca tgaaagcaag gactgtgcct tgcagctcag ggccagcctt
     8281 agtactagtc tctgagggac cgttgctacc accggttccc aacctgtagc agcacaacta
     8341 tcctggacca gggttcacgg atggagctca agaccttgac atctgtcaca gttatgctct
     8401 gcaccatgag gaagttgtct cagtttgcct tactgccaca gcaccggctg tgggctcagc
     8461 attgtgacac tcagagccac agttctggag caggaactag ggcaggtccc tctggtgatt
     8521 ctttctacag ttcacgacca gaggctgttg gctttggaag gcacctggag gtctgtgcaa
     8581 gccccggaca gaggcttgtg tagatgaagg accctttata aaaagctccc taattgagtc
     8641 ttgaaaaact cacccgctga ggatttagga gaaacctaag cttggatcgc ctcctaacac
     8701 tgccacaggt aacctgaatt ttggtgccat atagtgttag aaactatagg ctgagagaga
     8761 gaaaaaaaaa acattctttt ttcaatttct gaaaacaaac aaaaccaaaa caagccatat
     8821 tatgaagacc ggaataaata cctaatcctt tgtcctcgaa tgacatcaca catcaataag
     8881 aaccaaggat gtttaaggaa ctatgacctc atctgacagt ataaatataa aatgccagaa
     8941 accgtcaaga tagtaaccag tgtgggtgga tgctcatatg tgtactgtat tagttacttt
     9001 ttcattgttg tgataaaata ccacgactaa agcctgactt ataggagaag gaatttgtcc
     9061 tgtgttttca gagtgataag actccatcat ggcagggacg catggaagcc agcaacaggt
     9121 atgatgctgg ggcagcaagc tgagagctca catccaccac tgaaggcaca aaacagcaag
     9181 tgtgagctgg aagtggtgtg aggctatata ctagcaaagg ctgccctact gatacgctgt
     9241 ctccaggagg actgcgttcc ccaagcttct ctgatcatca caaccaactg aggactaaat
     9301 gttcaaatac ctgggtcagt ggggatcatt tctcattcaa acttccacag ataattaaaa
     9361 gcaaataaat gaaccaggtt taaggaaact tactgaattc caatagaaaa tatagaaata
     9421 aatcaatact ttagtagata taattgactg agacatgggg gcaaatttta aaaagttgaa
     9481 attcttgata atgaaggtat actaaacaaa ataaaattgc attagggaag cattgatgtt
     9541 agagtaaatc aagcagaaga gagaatgagt gaattccaag ataggccatt tgaaaatgca
     9601 cagaagagaa aaagaattaa gaggaagaaa tgtactcatg gtaaccttgg agcaacagtg
     9661 aaagggtaag taggttagtg gggatatgga cgggacttga gaacaccaaa ggagttaatc
     9721 gatgcaacta cgttatgatc aaccacagtc aggttccagg ttctgcagta aactgaatct
     9781 ccagttttca cgctatgtag atccatctcc atgaatctgg cctggccttg tgactttctg
     9841 gtaactgatt agttgaaagt tgcaaatata attgtttaac ttcttatgct agaattcaag
     9901 aagccttgca actattaccc tggtcctttg gagcgatgtc cctgacaagt gtgtccagtt
     9961 gaaatgcagc atccttacag agtctgactg agattgtcca acaaccttca gagcctaaga
    10021 cagcctcttg gaaactattc aattgttctg gccatcccag cccctagatg ccagagtaga
    10081 gaagtcacct tggatgttaa acaaactggt attggaggtt ggggataaac tcagtagtac
    10141 agagcttgcc tggcacgctc aagtacctag gttcaaactc tggcaatgcc aaaaaagaaa
    10201 aaagttgata gcaaactctc agatgattca ggttctagtt agcgtttgaa tggaattgta
    10261 tgagatggtc tcctgagccc tctcaatccc tgagagagaa tttttttgta agtcaatata
    10321 ttatgcaata atttgttata cagttgtact ggctaatttg ggtcaagctg gagttatcac
    10381 agagaaagga gcttcagttg gggaaatgcc tccatgagat ccaactgtaa ggcattttct
    10441 caattagtga tcaaggggga aaggcccctt gtgggtagga ccatctctgg gctggtagtc
    10501 ttggttctat aagagagcag gctgagcaag ccaggtgagg caagccagta aggaacatcc
    10561 ctccatggcc tctgtatcag ctcctgctcc tgacctgctt gagttccagt cctgacttcc
    10621 tttggtgatg aacagcaatg tggaaagtgt aagctgaata aaccctttcc tccccaattt
    10681 gcttagtggt catgatgttt tgtccaggaa tagaaaccct gactaagaca atagtaatag
    10741 gtaacaagaa gagagctgtg aactcgtcat gtagttaaga taagtgtttg ctagatttcc
    10801 tattgcatag ttcctatttt ctctttatat ttggaaaaaa attgtggtaa cataccttgg
    10861 acacttattg ttgttctccc ccctgacctg cactcaatgc tgaattctca gccaaactct
    10921 agtgatgtcc tccccattca aaagcttcaa ccttctagtc tttatttaaa aaaatgttat
    10981 tattacattt atttattctg tggtgtgtgt gtgtgagaga gaggatggga gcaggtgtgt
    11041 gtgtgtgtgt gtcggtgtgt ttgttaaatc agaacatgag tgtgtgtgta agacagagac
    11101 ggggtgagtg tgtgtgtgtg tgtatgggag caggtgtgtg tgtgtgtgtg ggtcagtgga
    11161 taagttgtgg aagtcagttc tttccttccc ttactcggat ctcagggatc aaacgcaagt
    11221 cctcaggttg ccaggtacat gtcacctgtc tttgctttat tattatttag ttctggcttt
    11281 tgagcctaag tgttatgtta cataggttga ccttgaatta gctatgcact gagctcctga
    11341 tcctcctgcc tatatcttcc aagtaatggt tacaggaatg ggccactgga cctagcaagt
    11401 gaacctacct ggtcactcca aaaatgcaca gcaaagaata tacgtttaaa aataggttca
    11461 ttttaggaag tttgtccaca ttttaaatga cagttctgtt aaagtatact gtgttttgtc
    11521 ctttgttaaa tgtgactttt aaaagcaatt caccttaata gcctgggcga ctacagtgct
    11581 cactgtataa atgctagtgt gtttttggtg ctgaaacaga aaggtggctc tagaaagctg
    11641 gagttcctca tctttaagtt ccagactgag atatctagaa cttcttcaaa aatccaggga
    11701 aaggaaagcg atggaagtga aaataaaaac aagaacatgc tttacatata tttgattgtg
    11761 atccctttgg cgggtactag gaaaaccacg gatggaattt tccttctaga aagaggtgag
    11821 gagcaggcag aatgtgaaca tctacttaat gagctgaact ggccggtgcc ctcagaattg
    11881 taaacaggta caccacaaat ccaggccttg gcagacagac caagtcttcc tctcttcggt
    11941 tttcttttta cagactggct ttcttgacaa cttcaagatg gagtctcatc cttgcccttt
    12001 ttatggagag gagaagcatt gcttctagtt ggttttagta gaggagtgaa gtgcatttct
    12061 cagatacaaa gagagcactt gagacgttcg gactcagaat ggccaagcct ggcactttgg
    12121 gaggtcaaga ggaggctgga acggctggga gagaaagcaa ttagatgttc cacccctttg
    12181 gtttttctcc agacagggtt tctctgtgta gccctgactg tcctgaagtt tgctctgtag
    12241 accaggctgg cctccaccca gggatttgcc tgcctctgcc tccccgagcc ccagattttt
    12301 atttttattt atatatatat taacttttga atgaacacaa tggaattgat gagcccttgg
    12361 agagtgaaac gggatgtcgt gcgtggcagc cccggggatc agctcactcc cacaggcctc
    12421 acaggccatg gagccaagag gcctccctgc ctcggcctcg gcctcggcct caacaaaggt
    12481 ggagaacgcg caggccgtcc gtccatgggg cgggaagtcg cgcgccgcgg ccgctgattg
    12541 gctggcgggc ccggtcgcct gatgctattt gttgtccccg cgccaatgac gcagtcggcg
    12601 tccggcgtcc acccgcacgt gcagccgttt aagccgcgtc ggccggccgc gaggagcccg
    12661 gggagcctgg agcggagagt taaccgccac catggatacc tacgccggag cctacgacag
    12721 acagagccgg gagagagaga acagcagcgc cgccagcccc gccacccaga gaagcgccaa
    12781 cgaggataag gccgccgatc tgcagagaga ggtggagagg gacggcggca gattcagatt
    12841 tgtgggccac ttcagcgagg cccctggcac cagcgccttc ggcaccgccg agagacccga
    12901 gttcgagaga atcctgaacg agtgtagggc cggcaggctg aacatgatca tcgtgtacga
    12961 cgtgtcccgg ttcagcaggc tgaaggtgat ggacgccatc cctatcgtgt ccgagctgct
    13021 ggccctgggc gtgaccatcg tgtccaccca ggaaggcgtc tttagacagg gcaacgtgat
    13081 ggacctgatc cacctgatca tgaggctgga cgccagccac aaggagagca gcctgaagag
    13141 cgccaagatc ctggacacca agaacctgca gagggagctg ggcggctatg tgggcggcaa
    13201 ggccccctac ggcttcgagc tggtgtccga gaccaaggag atcacccgga acggcaggat
    13261 ggtgaacgtg gtgatcaaca agctggccca cagcaccacc cccctgaccg gccccttcga
    13321 gtttgagccc gacgtgatca ggtggtggtg gcgggagatc aagacccaca agcacctgcc
    13381 tttcaagccc ggcagccagg ccgccatcca ccccggcagc atcaccggcc tgtgtaagag
    13441 aatggacgcc gacgccgtgc ccaccagagg cgagaccatc ggcaagaaaa ccgccagcag
    13501 cgcctgggac cccgccaccg tgatgagaat cctgagggac cctaggatcg ccggcttcgc
    13561 cgccgaggtg atctacaaga agaagcccga cggcaccccc accaccaaga tcgagggcta
    13621 cagaatccag agagacccca tcaccctgag acctgtggag ctggactgtg gccctatcat
    13681 cgagcctgcc gagtggtacg agctgcaggc ctggctggac ggcagaggca gaggcaaggg
    13741 cctgagcaga ggccaggcca tcctgagcgc catggacaag ctgtactgtg agtgtggcgc
    13801 cgtgatgacc agcaagagag gcgaggagag catcaaggac agctaccggt gccggagaag
    13861 aaaggtggtg gaccccagcg cccctggcca gcacgagggc acctgtaatg tgagcatggc
    13921 cgccctggac aagttcgtgg ccgagcggat cttcaacaag atccggcacg ccgagggcga
    13981 cgaggagacc ctggccctgc tgtgggaggc cgccagaaga ttcggcaagc tgaccgaggc
    14041 ccccgagaag agcggcgaga gggccaacct ggtggccgag agagccgacg ccctgaacgc
    14101 cctggaggag ctgtacgagg acagagccgc cggagcctat gacggccctg tgggcaggaa
    14161 gcacttcaga aagcagcagg ccgccctgac cctgagacag cagggcgccg aggaaagact
    14221 ggccgagctg gaggccgccg aggcccctaa gctgcccctg gatcagtggt tccccgagga
    14281 tgccgacgcc gaccccaccg gccccaagtc ctggtggggc agagccagcg tggacgacaa
    14341 gagggtgttc gtgggcctgt tcgtggataa gatcgtggtg accaagagca ccaccggcag
    14401 gggccagggc acccccatcg agaagagagc cagcatcacc tgggccaagc ctcccaccga
    14461 cgacgacgag gatgacgccc aggacggcac cgaggacgtg gccgccccta agaaaaagcg
    14521 gaaagtgtga tagatctaga gctcgctgat cagcctcgac tgtgccttct agttgccagc
    14581 catctgttgt ttgcccctcc cccgtgcctt ccttgaccct ggaaggtgcc actcccactg
    14641 tcctttccta ataaaatgag gaaattgcat cgcattgtct gagtaggtgt cattctattc
    14701 tggggggtgg ggtggggcag gacagcaagg gggaggattg ggaagacaat agcaggcatg
    14761 ctggggatgc ggtgggctct atggacgtcc tagagaagtt cctattccga agttcctatt
    14821 cttcaaaagg tataggaact tcgcggccgc ctagtaaggg gcgcgcccat catgctctca
    14881 ctgcctcctc agcttcaaga ggaatctgga aaaagcagtc ccactggtca ggaaaggaac
    14941 actagtgcac ttatcctggg tgtctgctga gccaacagtg gtagtaaggt aagggcagga
    15001 tgtgtcaaac tgccaataga gaactactta ctcttcaggc tgaagctgat ggaacaggta
    15061 acaaaggcaa acactaatca tgatcagcaa gatgaagcag aaagggaaca aggggatatt
    15121 aaatgtgtat agacacgcta gagagatggc tcagcagtta agagaactag ctggtctttc
    15181 agaggtcctg agatcaattt tagacaccca catggtggct catgaccatc tatctataaa
    15241 tggatctgat tttcatgtct ggcagtgtac agaagctaac tgaagaaagg tggaagaccc
    15301 acaagagttc aagataagcc ctatatagtg aagttcaagg caagcttttt ctacctgaaa
    15361 cttagtctca aaaaaaaatg aatacgtaaa cagtcttcca ggggataaga accttacaga
    15421 aaaagcagaa atgcctgggg cactggatta ccgatgtaat caaattcagt ccttgaattg
    15481 aacacaggat tgcctagagc aaggccagcc agagattcat ctcagaggga gaaaggtgtc
    15541 tttggagcaa ttttgtggta atctagtatg tatcacataa gtttagacgc atttgggact
    15601 ggaaagatgt gaacaaagca ccctatggct cacatctgtc attaactcta gttccagtgc
    15661 acctgacacc gtcttctggc ctctgcagtg accaagcaca tgggtagtat gtagacatat
    15721 acataagcaa aacacacatc attaaaaagt gacatttccc aaaggaagct gaagaaccag
    15781 ttcttgagaa gatagtagaa atcagaaggg gaaatagtag acatacagag ggactgacca
    15841 ggttgtgtca cctttatagg ctaggctaat ggatgatcga cactagcgct ctttgtgaag
    15901 gacacacaaa tgagacatag tttataggac taaacacact tctaagcaat ttaatgagac
    15961 ttaagaccct gtctctagca aatactctgg atgatattca gctcaaggct cttgtcagac
    16021 atgtttccat tttcaaggtg agctaactgg ccaaaactgc caacaacctg tagtgaatag
    16081 agaagatgag aaaatctgga ttctcaaatg acctaatgaa agccactgga gcgccatatg
    16141 gtttctgtga aaatgccttt tcaatcatta acctcttaaa tgagtgttag catcctaact
    16201 aatgagtggt gcagaatagt gggtctgctt agcttaacta aggccaagaa aacaaaacag
    16261 gaaattcatt ccatgtcatg agactcatac tacgaggttc ccttagacct caggagaaaa
    16321 agtctttggc tgtaagaaca cacctcagtg gatgtggtag actatgcctt tactcttttt
    16381 tttttttttt tttttttttg ggttttttcg agacagggtt tctctgtgta gccttggctg
    16441 tcctggaact cactttgttg accaggctgg cctcgaactc agagatccgc ctgcctctgc
    16501 ctctcaagtg ctagaattaa aagtgtgcgc caccactccc agctatatag actatgcctt
    16561 taatcaggac acttgggagg cagggggatc tcaaattcaa ttccagacag atgactgaca
    16621 aacacacaca tacaccattc gtcttttctt tttttctttt ttcttttgaa aacaggtttc
    16681 tctatgcagc cctggctttc ctagaattca atctatagac ccagctggcc tcaaacacag
    16741 aacctcttgc ctctgcctcc tcaacactat gactaaaggt gtgaaccacc accaccacca
    16801 cccacctggc caaagaatga attgagtgaa taagtacgag tgcaactctc cagcagcctg
    16861 aggcaagaaa gcttaacagt tgaacctgag accctacttc gtttgtgttg tacatatctt
    16921 ctcataatga actaggcagc ctagtctctc taccaaatac accatgcact tacacctcct
    16981 caaaccaact gcaacagcta cacacatttc catggcttgc ctgtaataat aaattcacaa
    17041 acttcctcta agtaactttt agtggaaatc taccaggtta tgcctatttg tgattgggtg
    17101 cacagatgac tagatgagat gtaatttggg aagtgacatg caataggaaa aatgaatata
    17161 taacctataa atagaaaaca ccaaggcaag cgtggtgact cacaccttta attagcactt
    17221 gggaggcaga agtcgcatca tctcttaggt caaggccaat ctagttccag accagcaagg
    17281 acaacagaaa ccttgccttg atataaacat tttaaaactt taaaaataga gaagcccaaa
    17341 ctctgctcat tggtaatcta cccttccttt ctttagacac cttgagaagc taggctacat
    17401 agctttgggt ccttacgtac ccccactcac tcagcctgca gtcaatctct gatagtgttt
    17461 cctgccataa gctacactac tgttttgctc caaaccttac ttctagtaca aatccatgtg
    17521 aggtcttcgt ttcaatttgg gggggaagag gccagaacac ttgccgcaga tcccaacaac
    17581 gggcagcaca ttcccagcta gtgtatctga tacaaactct atcttcattc agaaccatca
    17641 agtctaagcc ccaagagcaa aggtaaattc atgtatgttt ggctggagaa agcatttcaa
    17701 gtcaaggtga gccttgaact cctaacactc ttgcctctac cttccaaatg ccaatatagg
    17761 tatttgtcac accagcttct caaatcctgt tgggctagca actgggtcga cggtatcgat
    17821 aagcttgata tcgaattcta ccgggtaggg gaggcgcttt tccaaggcag tctgagcatg
    17881 cgcttagcag ccccgctggc acttggcgct acacaagtgg cctytggcct cgcacacatt
    17941 ccacatccac cggtaggcgc caaccggctc cgttctttgg tggccccttc gcgccacctt
    18001 ctwctcctcc cctagtcagg aagttccccc ccgccccgca gctcgcgtcg tsaggacgtg
    18061 acaaatggaa gtagcacgtc tcactagtct cgtcagatgg acagcaccgc tgagcaatgg
    18121 aagcgggtag gcctttgggg cagcggccaa tagcagcttt gctccttcgc tttctgggct
    18181 cagaggctgg gaaggggtgg gtccgggggc gggctcaggg gcgggctcag gggcggggcg
    18241 ggcgcccgaa ggtcctccgg aggcccggca ttctgcacgc ttcaaaagcg cacgtctgcc
    18301 gcgctgttct cctcttcctc atctccgggc ctttcgacct gcaggtcctc gccatggatc
    18361 ctgatgatgt tgttattctt ctaatctttt gtatggaaaa cttttcttcg taccacggga
    18421 ctaaacctgg ttatgtagat tccattcaaa aaggtataca aaagccaaaa tctggtacac
    18481 aaggaaatta tgacgatgat tggaaagggt tttatagtac cgacaataaa tacgacgctg
    18541 cgggatactc tgtagataat gaaaacccgc tctctggaaa agctggaggc gtggtcaaag
    18601 tgacgtatcc aggactgacg aaggttctcg cactaaaagt ggataatgcc gaaactatta
    18661 agaaagagtt aggtttaagt ctcactgaac cgttgatgga gcaagtcgga acggaagagt
    18721 ttatcaaaag gttcggtgat ggtgcttcgc gtgtagtgct cagccttccc ttcgctgagg
    18781 ggagttctag cgttgaatat attaataact gggaacaggc gaaagcgtta agcgtagaac
    18841 ttgagattaa ttttgaaacc cgtggaaaac gtggccaaga tgcgatgtat gagtatatgg
    18901 ctcaagcctg tgcaggaaat cgtgtcaggc gatctctttg tgaaggaacc ttacttctgt
    18961 ggtgtgacat aattggacaa actacctaca gagatttaaa gctctaaggt aaatataaaa
    19021 tttttaagtg tataatgtgt taaactactg attctaattg tttgtgtatt ttagattcca
    19081 acctatggaa ctgatgaatg ggagcagtgg tggaatgcag atcctagagc tcgctgatca
    19141 gcctcgactg tgccttctag ttgccagcca tctgttgttt gcccctcccc cgtgccttcc
    19201 ttgaccctgg aaggtgccac tcccactgtc ctttcctaat aaaatgagga aattgcatcg
    19261 cattgtctga gtaggtgtca ttctattctg gggggtgggg tggggcagga cagcaagggg
    19321 gaggattggg aagacaatag caggcatgct ggggatgcgg tgggctctat ggcttctgag
    19381 gcggaaagaa ccagctgggg ctcgacctcg agggggggcc cggtacccag cttttgttcc
    19441 ctttagtgag ggttaattgc gcgcttggcg taatcatggt catagctgtt tcctgtgtga
    19501 aattgttatc cgctcacaat tccacacaac atacgagccg gaagcataaa gtgtaaagcc
    19561 tggggtgcct aatgagtgag ctaactcaca ttaattgcgt tgcgctcact gcccgctttc
    19621 cagtcgggaa acctgtcgtg ccagctgcat taatgaatcg gccaacgcgc ggggagaggc
    19681 ggtttgcgta ttgggcgctc ttccgcttcc tcgctcactg actcgctgcg ctcggtcgtt
    19741 cggctgcggc gagcggtatc agctcactca aaggcggtaa tacggttatc cacagaatca
    19801 ggggataacg caggaaagaa catgtgagca aaaggccagc aaaaggccag gaaccgtaaa
    19861 aaggccgcgt tgctggcgtt tttccatagg ctccgccccc ctgacgagca tcacaaaaat
    19921 cgacgctcaa gtcagaggtg gcgaaacccg acaggactat aaagatacca ggcgtttccc
    19981 cctggaagct ccctcgtgcg ctctcctgtt ccgaccctgc cgcttaccgg atacctgtcc
    20041 gcctttctcc cttcgggaag cgtggcgctt tctcatagct cacgctgtag gtatctcagt
    20101 tcggtgtagg tcgttcgctc caagctgggc tgtgtgcacg aaccccccgt tcagcccgac
    20161 cgctgcgcct tatccggtaa ctatcgtctt gagtccaacc cggtaagaca cgacttatcg
    20221 ccactggcag cagccactgg taacaggatt agcagagcga ggtatgtagg cggtgctaca
    20281 gagttcttga agtggtggcc taactacggc tacactagaa ggacagtatt tggtatctgc
    20341 gctctgctga agccagttac cttcggaaaa agagttggta gctcttgatc cggcaaacaa
    20401 accaccgctg gtagcggtgg tttttttgtt tgcaagcagc agattacgcg cagaaaaaaa
    20461 ggatctcaag aagatccttt gatcttttct acggggtctg acgctcagtg gaacgaaaac
    20521 tcacgttaag ggattttggt catgagatta tcaaaaagga tcttcaccta gatcctttta
    20581 aattaaaaat gaagttttaa atcaatctaa agtatatatg agtaaacttg gtctgacagt
    20641 taccaatgct taatcagtga ggcacctatc tcagcgatct gtctatttcg ttcatccata
    20701 gttgcctgac tccccgtcgt gtagataact acgatacggg agggcttacc atctggcccc
    20761 agtgctgcaa tgataccgcg agacccacgc tcaccggctc cagatttatc agcaataaac
    20821 cagccagccg gaagggccga gcgcagaagt ggtcctgcaa ctttatccgc ctccatccag
    20881 tctattaatt gttgccggga agctagagta agtagttcgc cagttaatag tttgcgcaac
    20941 gttgttgcca ttgctacagg catcgtggtg tcacgctcgt cgtttggtat ggcttcattc
    21001 agctccggtt cccaacgatc aaggcgagtt acatgatccc ccatgttgtg caaaaaagcg
    21061 gttagctcct tcggtcctcc gatcgttgtc agaagtaagt tggccgcagt gttatcactc
    21121 atggttatgg cagcactgca taattctctt actgtcatgc catccgtaag atgcttttct
    21181 gtgactggtg agtactcaac caagtcattc tgagaatagt gtatgcggcg accgagttgc
    21241 tcttgcccgg cgtcaatacg ggataatacc gcgccacata gcagaacttt aaaagtgctc
    21301 atcattggaa aacgttcttc ggggcgaaaa ctctcaagga tcttaccgct gttgagatcc
    21361 agttcgatgt aacccactcg tgcacccaac tgatcttcag catcttttac tttcaccagc
    21421 gtttctgggt gagcaaaaac aggaaggcaa aatgccgcaa aaaagggaat aagggcgaca
    21481 cggaaatgtt gaatactcat actcttcctt tttcaatatt attgaagcat ttatcagggt
    21541 tattgtctca tgagcggata catatttgaa tgtatttaga aaaataaaca aataggggtt
    21601 ccgcgcacat ttccccgaaa agtgccacct aaattgtaag cgttaatatt ttgttaaaat
    21661 tcgcgttaaa tttttgttaa atcagctcat tttttaacca ataggccgaa atcggcaaaa
    21721 tcccttataa atcaaaagaa tagaccgaga tagggttgag tgttgttcca gtttggaaca
    21781 agagtccact attaaagaac gtggactcca acgtcaaagg gcgaaaaacc gtctatcagg
    21841 gcgatggccc actacgtgaa ccatcaccct aatcaagttt tttggggtcg aggtgccgta
    21901 aagcactaaa tcggaaccct aaagggagcc cccgatttag agcttgacgg ggaaagccgg
    21961 cgaacgtggc gagaaaggaa gggaagaaag cgaaaggagc gggcgctagg gcgctggcaa
    22021 gtgtagcggt cacgctgcgc gtaaccacca cacccgccgc gcttaatgcg ccgctacagg
    22081 gcgcgtccca ttcgccattc aggctgcgca actgttggga agggcgatcg gtgcgggcct
    22141 cttcgctatt acgccagctg gcgaaagggg gatgtgctgc aaggcgatta agttgggtaa
    22201 cgccagggtt ttcccagtca cgacgttgta aaacgacggc cagtgagcgc gcgtaatacg
    22261 actcactata gggcgaattg gagctcca
//
