LOCUS       sequence-92626-e         839 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses GoF mutant murine PCSK9 to be used for rAAV8-mediated gene
            transfer, hypercholesterolemia and atherosclerosis.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Bjorklund MM, Hollensen AK, Hagensen MK, Dagnaes-Hansen F, 
            Christoffersen C, Mikkelsen JG, Bentzon JF
  TITLE     Induction of atherosclerosis in mice and hamsters without germline 
            genetic engineering.
  JOURNAL   Circ Res. 2014 May 23;114(11):1684-9. doi: 
            10.1161/CIRCRESAHA.114.302937. Epub 2014 Mar 27.
  PUBMED    24677271
REFERENCE   2  (bases 1 to 839)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1161/CIRCRESAHA.114.302937"; journalName: "Circ Res"; date: 
            "2014-05-23- 23"; volume: "114"; issue: "11"; pages: "1684-9"
COMMENT     Sequence Label: pAAV/D377Y-mPCSK9
FEATURES             Location/Qualifiers
     source          1..839
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 acagatggct ggcaactaga aggcacaggc cggcctcact gaacccagga ggcctttgct
       61 gaaggccggc tccggcagca gatggcagca gctactgtgg cttctccact ggtcctgtct
      121 gctctggcag tgtcatggac tcttgccaca cacaggttgt ccacgctgta ggctcccaga
      181 gtgagggatg ccccagggag cacattgcat ccagtcaggg tccatcctgc ttcgcaggcc
      241 acagtgacct gctctgaagg acctgagatc ccatgctcct tgattttgca ttccagccct
      301 ggggcatggc agcaggaagc atagacactg gccgcctggt ggccaacgca ctggccaggc
      361 tgacgtctgg acctcagcgc aggctgcctc cggacactaa ggtcttccac ttcccaatgg
      421 aagctgcagc ctgtgagaac atggtccttc tggtggcagt ggacatgggt ctccaggcca
      481 gctctggctg caggggtgtt gtggatgctg cagttggcac ggggaaccag gcagcatctc
      541 gcgacggcat agacaccctc acccccaaat gcattgaggg ccttgcagac ctgctggcct
      601 cctatggcct caatccaatc accacgacgc ctcccgctcc tggagaagct ggagcagctc
      661 agcagctcct cttctggggc acagcgggct gtagctgtag ctgttcgagt gggccccgag
      721 tgtgccgacc acaccgtcct acagagcagc tgcccgcctg tctcatgggt gctggggggc
      781 agtgtggcca ccaggttggg ggtcagcacc tgctggtcct cagggaacca ggccatgtt
//
