LOCUS       sequence-95115-e         686 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses GoF mutant murine PCSK9 to be used for rAAV8-mediated gene
            transfer, hypercholesterolemia and atherosclerosis.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Bjorklund MM, Hollensen AK, Hagensen MK, Dagnaes-Hansen F, 
            Christoffersen C, Mikkelsen JG, Bentzon JF
  TITLE     Induction of atherosclerosis in mice and hamsters without germline 
            genetic engineering.
  JOURNAL   Circ Res. 2014 May 23;114(11):1684-9. doi: 
            10.1161/CIRCRESAHA.114.302937. Epub 2014 Mar 27.
  PUBMED    24677271
REFERENCE   2  (bases 1 to 686)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1161/CIRCRESAHA.114.302937"; journalName: "Circ Res"; date: 
            "2014-05-23- 23"; volume: "114"; issue: "11"; pages: "1684-9"
COMMENT     Sequence Label: pAAV/D377Y-mPCSK9
FEATURES             Location/Qualifiers
     source          1..686
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 cagccctcgg ggccactcgt ggttctgctg cccctggccg gtgggtatag ccgcatcctc
       61 aacgctgcct gccggcacct ggcgaggact ggggtggtgc tggttgcagc agctgggaac
      121 ttccgggacg acgcctgcct ctactcccca gcttctgctc cagaggtcat cacagtcggg
      181 gccacgaatg cccaggacca gccagttacc ttggggactt tggggactaa ttttggacgc
      241 tgtgtggatc tctttgcccc cgggaaggac atcatcggag cgtccagtta ctgcagcaca
      301 tgcttcatgt cacagagtgg gacctcacag gctgctgccc acgtggccgg cattgtggct
      361 cggatgctga gccgggagcc cacacttacc ctggccgagc tgcggcagag gctgatccac
      421 ttctctacca aagacgtcat caacatggcc tggttccctg aggaccagca ggtgctgacc
      481 cccaacctgg tggccacact gccccccagc acccatgaga caggcgggca gctgctctgt
      541 aggacggtgt ggtcggcaca ctcggggccc actcgaacag ctacagctac agcccgctgt
      601 gccccagaag aggagctgct gagctgctcc agcttctcca ggagcgggag gcgtcgtggt
      661 gattggattg aggccatagg aggcca
//
