CRISPR nucleases are remarkably precise molecular tools for cutting DNA. But “remarkably precise” does not mean “perfectly specific.” In reality, CRISPR nucleases occasionally make mistakes and cleave DNA sequences that only resemble the intended target. These unintended cuts cause the …

Deaminet 2026, held in Palm Springs in late January, brought together researchers studying deaminase enzymes across disciplines: from structural biologists resolving APOBEC proteins at atomic resolution, to cancer biologists dissecting mutational processes, to medical researchers advancing base and prime editing …

Do you have a green thumb — or, perhaps, are you one of those people who kills every plant they touch? The whole trouble with houseplants is they can’t bark, meow, or cry when they need something. But what if …