382 results

1. scQers promoter control #5 (high: EEF1A1 promoter, p028)

   Pooled Library

   #217424

   Purpose

   scQers promoter control #5 (high: EEF1A1 promoter, p028)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

2. BARBEKO sgRNA library

   Pooled Library

   #174163

   Purpose

   iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

   Depositor

   Wensheng Wei

   Article

   Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

3. scQers promoter control #2 (low: no promoter, p029)

   Pooled Library

   #217421

   Purpose

   scQers promoter control #2 (low: no promoter, p029)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

4. scQers promoter control #3 (intermediate: UBC promoter, p041)

   Pooled Library

   #217422

   Purpose

   scQers promoter control #3 (intermediate: UBC promoter, p041)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

5. scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Pooled Library

   #217423

   Purpose

   scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

6. pre-associated oBC-mBC backbone (p025)

   Pooled Library

   #194097

   Purpose

   pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

7. TRE-MPRA_minTK Library

   Pooled Library

   #201014

   Purpose

   Massively parallel reporter assay (MPRA) library with minTK promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available Since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Mouse Cherry Brie Pooled Library

   Pooled Library

   #170511

   Purpose

   CRISPR library targeting mouse genes

   Depositor

   Pavel Tolar

   Article

   Newman et al biorXiv 2021.03.02.433398

   Expression

   Mammalian

   Species

   Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

9. Ma-PylRS-lib1

   Pooled Library

   #224585

   Purpose

   Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

   Depositor

   Ryan Mehl

   Article

   Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

   Expression

   Bacterial

   Species

   Methanomethylophilus alvus

   Available Since

   Jan. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

10. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Human genome-wide CRISPR guide RNA library V1 (pKLV2-U6gRNA5(HumanV1)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

11. Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #101927

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression

    Pooled Library

    #101928

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

14. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library

    #174592

    Purpose

    CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

    Depositor

    Juan Bonifacino

    Article

    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

15. psgRNA Library

    Pooled Library

    #115927

    Purpose

    Genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available Since

    June 6, 2019

    Availability

    Academic Institutions and Nonprofits only

16. Mouse SLC KO Library

    Pooled Library

    #141436

    Purpose

    Expresses gRNAs for knockout of the mouse Solute Carrier family

    Depositor

    Giulio Superti-Furga

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

17. Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

    Pooled Library

    #101926

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

18. hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

    Pooled Library

    #83976

    Purpose

    Human CRISPRi Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

    Pooled Library

    #83985

    Purpose

    Human CRISPRa Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

20. Liu Lab MusCK (A + B)

    Pooled Library

    #1000000178

    Depositor

    Xiaole Shirley Liu

    Available Since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only