...similar 3D structure to MEK1, but Raf1 and CDK5 have less similarity. For these three kinases, photoswitchable...photoswitchable versions of MEK1, MEK2, Raf1, and CDK5 all behave similarly to their endogenous counterparts... figure). Zhou et al also used a photoswitchable CDK5 in C. elegans. See figures 4B and C in Zhou et al...other photoswitchable kinases: psMEK2, psRaf1, and psCDK5. MEK2 is a serine/threonine kinase with a similar...

...photoswitchable Intersectin, Cdc42, Raf1, Mek1, Mek2, Cdk5, and Cas9. Xin has demonstrated the utility of these...