The PAM Requirement and Expanding CRISPR Beyond SpCas9
Type
Blog Post
Published
Aug. 20, 2020, 2:30 p.m.
...same species.
Expanding the CRISPR toolbox
The isolation of novel CRISPR proteins has and will continue...dramatically increase the number of CRISPR applications. The first non-Cas9 CRISPR protein adapted for genome ...trying to decide which CRISPR tools are best for your experiment, check out our CRISPR guide or leave a comment...Check out our CRISPR Featured Topic Page
Resources on Addgene.org
Check out our CRISPR Guide
Browse ...variants effectively double the targeting range of CRISPR/Cas9 within the human genome.
Another variant, ...AT-rich genomes (Kleinstiver et al., 2016).
Type VI CRISPR systems, which target RNA, offer additional targeting...the flexibility of this system.
As the number of CRISPR reagents continues to grow, so too will the number...