Mammalian RNA Interference Vectors

Several laboratories have deposited plasmids for mammalian RNA interference experiments at Addgene's non-profit plasmid repository. This website describes some of the empty vectors that you can use to clone shRNAs.

You may request these plasmids through Addgene at a nominal cost. To obtain a plasmid, Login or Register a new account. Find your plasmid of interest, then click the Add to Cart button. When you are finished adding plasmids to your cart, complete the checkout process online. For information on Addgene's pricing and distribution policy, please click here.

 
Click here to browse other RNAi plasmids from Addgene's repository.

Nature Methods has published a user's guide to RNA interference in mammalian cells. Further information for many of Addgene's RNAi vectors can be found in these articles.

Addgene stores plasmids submitted by scientists and distributes them for use in advancing life science research. Click here to learn more about Addgene's repository.