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Antigen Processing and Presentation Icon Immunology Research Plasmids and Resources


Mammalian organisms are exposed to millions of potential pathogens each day. Their ability to protect against infection depends on two systems that work in concert: the innate and adaptive immune systems.

Upon infection, the immune system triggers several processes to activate cells to recognize and get rid of infectious pathogens. The innate immune response is triggered within the first few minutes of exposure to a pathogen and is the dominant defense strategy during the first several days following exposure to a pathogen. The innate immune system is not specific to any particular pathogen. It includes physical barriers such as the skin and mucosa, antimicrobial peptides and proteins in the blood such as interferons and complement, and specialized cells such as macrophages and neutrophils that attack invading pathogens.

Innate immune cells also process and present foreign antigens to adaptive immune cells, such as T cells and B cells. About a week following the initial exposure to a pathogen, the adaptive immune response kicks in. The adaptive immune response is antigen-specific and includes cellular and humoral immunity. Once an adaptive immune cell is primed to recognize a specific antigen, it finds and attacks pathogens or infected cells expressing that antigen. Antibodies produced by B cells activate immune components that also lead to the destruction of pathogens. Over the course of an infection, adaptive immune cells will expand and give rise to memory cells that can recognize a recurrent infection and rapidly initiate a secondary immune response.

Browse Plasmids for Immunology Research

Genes have been grouped into tables based on the Gene Lists from Immport. Click the links below to go to the gene table for each category. The gene names in these tables link to the available plasmids for each gene. Please note that not all genes have plasmids available for request.

Antigen Processing and Presentation Icon Antigen Presentation The cornerstone of the immune response is the recognition by T cells of foreign antigens on the surface of antigen presenting cells (APC) including dendritic cells and macrophages. Antigen presentation is mediated by the MHC class I and class II molecules found on the surface of APC.
BCR signaling icon BCR Signaling B cells mediate humoral immunity through the secretion of antibodies, and also function as antigen presenting cells. B cells in secondary lymphoid organs recognize specific antigens through the B cell receptor (BCR). The strength and duration of signaling controls the fate of B cells and can lead to the formation of a high avidity BCR through repeat cycles of expansion.
Chemokines Icon Chemokines
Chemokines, or chemotactic cytokines, are small proteins that can be secreted by immune cells and other cell types. They can be grouped in to the CC, CXC, XC, and CX3C families based on conserved cysteine residues. Chemokines recruit innate and adaptive immune cells to sites of inflammation throughout the body.
Cytokines Icon Cytokines
Cytokines are molecules that enable cells of the immune system to communicate with each other across long distances. During infection and inflammation, the different cytokines that are released tailor the immune response to a specific trigger.
Cytokines Icon Interferons
The interferon family of signaling proteins consists of Type I, Type II, and Type III interferons. They trigger the defensive responses of the immune system upon infection with virus and, like other cytokines, enable communication between cells of the immune system.
Cytokines Icon Interleukins
Interleukins are cytokines that are secreted by immune cells and coordinate communication between immune cells over the course of an immune response. Over 60 interleukins have been described.
NK cell cytotoxicity icon NK Cell Signaling Natural killer (NK) cells can kill cells that have been infected by a foreign pathogen. They detect infected cells via receptors such as KIR and NKG2D. Upon activation, NK cells secrete perforin and granzyme B, two enzymes that create pores within an infected cell membrane, triggering cell death.
TCR signaling icon TCR Signaling The T cell receptor (TCR) engages with antigen presenting cells of the innate immune system. Engagement of the TCR by an MHC molecule presenting its cognate antigen along with co-stimulation activates the T cell, whereas T cell tolerance or anergy are induced when the TCR is engaged without co-stimulation or with a low affinity antigen.
TGF beta icon TGFbeta
In the immune system, Tumour Growth Factor beta (TGFbeta) signaling and its downstream effector molecules, the Smad proteins, regulate the adaptive immune response through effects on numerous immune cell types including T cells and B cells. It also impacts the development and function of innate immune cells including NK cells, macrophages, dendritic cells, and granulocytes.
TGF beta icon TLR The toll like receptors (TLR) play a key role in the innate immune system. They are found on dendritic cells and macrophages and sense conserved microbial molecules during an infection. When TLRs sense a microbial pathogen, they trigger signalling pathways that lead to the activation of an immune response.
TGF beta icon TNF
The tumor necrosis factor (TNF) family of proteins are predominantly expressed by immune cells and help to regulate the immune response and inflammation. They act as cytokines when cleaved from the cell membrane and can also function as signaling proteins involved in proliferation, cell differentiation, and apoptosis.

Plasmid Tables

The gene names in these tables link to the available plasmids for each gene. Please note that not all genes have plasmids available for request.

Antigen Processing and Presentation Icon Antigen Processing and Presentation

The cornerstone of the immune response is the recognition by T cells of foreign antigens on the surface of antigen presenting cells (APC) including dendritic cells and macrophages. Antigen presentation is mediated by the MHC class I and class II molecules found on the surface of APC.

Symbol Name Synonyms
ADRM1 adhesion regulating molecule 1 ARM1, GP110, MGC29536, Rpn13
AP3B1 adaptor-related protein complex 3, beta 1 subunit ADTB3, ADTB3A, HPS, HPS2, PE
AZGP1 alpha-2-glycoprotein 1, zinc-binding ZA2G, ZAG
B2M beta-2-microglobulin -
CALR calreticulin CRT, FLJ26680, RO, SSA, cC1qR
CANX calnexin CNX, FLJ26570, IP90, P90
CD1A CD1a molecule CD1, FCB6, HTA1, R4, T6
CD1B CD1b molecule CD1, CD1A, MGC125990, MGC125991, R1
CD1C CD1c molecule BDCA1, CD1, CD1A, R7
CD1D CD1d molecule CD1A, MGC34622, R3
CD1E CD1e molecule CD1A, R2
CD209 CD209 molecule CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, MGC129965
CD4 CD4 molecule CD4mut
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain DHLAG, HLADG, Ia-GAMMA
CD8A CD8a molecule CD8, Leu2, MAL, p32
CD8B CD8b molecule CD8B1, LYT3, Leu2, Ly3, MGC119115
CIITA class II, major histocompatibility complex, transactivator C2TA, CIITAIV, MHC2TA, NLRA
CLEC4M C-type lectin domain family 4, member M CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866
CREB1 cAMP responsive element binding protein 1 CREB, MGC9284
CTSB cathepsin B APPS, CPSB
CTSE cathepsin E CATE
CTSL1 cathepsin L1 CATL, CTSL, FLJ31037, MEP
CTSS cathepsin S MGC3886
ERAP1 endoplasmic reticulum aminopeptidase 1 A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, KIAA0525, PILS-AP, PILSAP
ERAP2 endoplasmic reticulum aminopeptidase 2 FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide FCRG
FCGRT Fc fragment of IgG, receptor, transporter, alpha FCRN, alpha-chain
HFE hemochromatosis HFE1, HH, HLA-H, MGC103790, MVCD7, dJ221C16.10.1
HLA-A major histocompatibility complex, class I, A FLJ26655, HLAA
HLA-B major histocompatibility complex, class I, B AS, HLA-B-7301, HLA-B73, HLAB, HLAC, MGC111087, SPDA1
HLA-C major histocompatibility complex, class I, C D6S204, FLJ27082, HLA-Cw, HLA-Cw12, HLA-JY3, HLC-C, PSORS1
HLA-DMA major histocompatibility complex, class II, DM alpha D6S222E, DMA, HLADM, RING6
HLA-DMB major histocompatibility complex, class II, DM beta D6S221E, RING7
HLA-DOA major histocompatibility complex, class II, DO alpha HLA-DNA, HLA-DZA, HLADZ
HLA-DOB major histocompatibility complex, class II, DO beta DOB
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 HLA-DP1A, HLADP, HLASB
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 DPB1, HLA-DP1B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 CD, CELIAC1, DQ-A1, FLJ27088, FLJ27328, GSE, HLA-DQA, MGC149527
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 HLA-DXA
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 CELIAC1, HLA-DQB, IDDM1
HLA-DRA major histocompatibility complex, class II, DR alpha HLA-DRA1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 DRB1, FLJ75017, FLJ76359, HLA-DR1B, HLA-DRB, HLA-DRB1*, SS1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 HLA-DR3B, HLA-DR52, MGC117330
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 DRB4, HLA-DR4B
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 FLJ76359, HLA-DRB
HLA-E major histocompatibility complex, class I, E DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
HLA-F major histocompatibility complex, class I, F CDA12, HLA-5.4, HLA-CDA12, HLAF
HLA-G major histocompatibility complex, class I, G MHC-G
HLA-H major histocompatibility complex, class I, H (pseudogene) HLAHP
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 FLJ31884, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 D6S182, FLJ26984, HSP90-BETA, HSP90B, HSPC2, HSPCB
HSPA1A heat shock 70kDa protein 1A FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B
HSPA1B heat shock 70kDa protein 1B FLJ54328, HSP70-1B, HSP70-2, HSPA1A
HSPA1L heat shock 70kDa protein 1-like HSP70-1L, HSP70-HOM, HSP70T, hum70t
HSPA2 heat shock 70kDa protein 2 HSP70-2, HSP70-3
HSPA4 heat shock 70kDa protein 4 APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) BIP, FLJ26106, GRP78, MIF2
HSPA6 heat shock 70kDa protein 6 (HSP70B') -
HSPA8 heat shock 70kDa protein 8 HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71
ICAM1 intercellular adhesion molecule 1 BB2, CD54, P3.58
IFI30 interferon, gamma-inducible protein 30 GILT, IFI-30, IP30, MGC32056
IFNA1 interferon, alpha 1 IFL, IFN, IFN-ALPHA, IFNA13, [email protected], MGC138207, MGC138505, MGC138507
IFNA10 interferon, alpha 10 MGC119878, MGC119879
IFNA13 interferon, alpha 13 -
IFNA14 interferon, alpha 14 LEIF2H, MGC125756, MGC125757
IFNA16 interferon, alpha 16 -
IFNA17 interferon, alpha 17 IFNA, INFA, LEIF2C1
IFNA2 interferon, alpha 2 IFNA, INFA2, MGC125764, MGC125765
IFNA21 interferon, alpha 21 MGC126687, MGC126689
IFNA4 interferon, alpha 4 INFA4, MGC142200
IFNA5 interferon, alpha 5 INFA5
IFNA6 interferon, alpha 6 -
IFNA7 interferon, alpha 7 IFNA-J
IFNA8 interferon, alpha 8 -
IFNG interferon, gamma IFG, IFI
KIAA0368 KIAA0368 ECM29, FLJ22036, KIAA1962, RP11-386D8.2
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 CD158B1, CD158b, NKAT6, p58.2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 CD158D, G9P, KIR103, KIR103AS
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 CD158H, CD158a, p50.1
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 NKAT7
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 CD158I, KIR1D, KIR412, KKA3, MGC120019, MGC125315, MGC125317, NKAT8
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 CD158G, NKAT9
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 CD158E1, KIR, MGC119726, MGC119728, MGC126589, MGC126591, NKAT3, NKB1, NKB1B
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 CD158K, MGC125321, NKAT4, NKAT4B, p140
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 CD158Z, KIR3DL7, KIR44, KIRC1
KLRC1 killer cell lectin-like receptor subfamily C, member 1 CD159A, MGC13374, MGC59791, NKG2, NKG2A
KLRC2 killer cell lectin-like receptor subfamily C, member 2 CD159c, MGC138244, NKG2-C, NKG2C
KLRC3 killer cell lectin-like receptor subfamily C, member 3 NKG2-E, NKG2E
KLRC4 killer cell lectin-like receptor subfamily C, member 4 FLJ17759, FLJ78582, NKG2-F, NKG2F
KLRD1 killer cell lectin-like receptor subfamily D, member 1 CD94
LGMN legumain AEP, LGMN1, PRSC1
LTA lymphotoxin alpha (TNF superfamily, member 1) LT, TNFB, TNFSF1
MICA MHC class I polypeptide-related sequence A FLJ60820, MGC111087, PERB11.1
MICB MHC class I polypeptide-related sequence B PERB11.2
MR1 major histocompatibility complex, class I-related HLALS
NFYA nuclear transcription factor Y, alpha CBF-A, CBF-B, FLJ11236, HAP2, NF-YA
NFYB nuclear transcription factor Y, beta CBF-A, CBF-B, HAP3, NF-YB
NFYC nuclear transcription factor Y, gamma CBF-C, CBFC, DKFZp667G242, FLJ45775, H1TF2A, HAP5, HSM, NF-YC
PDIA2 protein disulfide isomerase family A, member 2 PDA2, PDI, PDIP, PDIR
PDIA3 protein disulfide isomerase family A, member 3 ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
PROCR protein C receptor, endothelial (EPCR) CCCA, CCD41, CD201, EPCR, MGC23024, bA42O4.2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) D6S216, D6S216E, LMP7, MGC1491, PSMB5i, RING10, beta5i
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 MGC24583, MGC8541, P26S4, S4, p56
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 MGC3004, MSS1, Nbla10058, S7
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 MGC8487, TBP1
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP7
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 CADP44, MGC12520, P44, SUG2, p42
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 MGC133040, MGC133041, P112, Rpn2, S1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 dJ889N15.2, p28
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 MGC3844, Rpn6, S9, p44.5
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 HSPC027, Rpn9, S11, p40.5
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 PAD1, POH1, rpn11
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 MGC14274, P97, Rpn1, S2, TRAP2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 P58, RPN3, S3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 KIAA0072, MGC23145, S5B
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 KIAA0107, Rpn7, S10, SGA-113M, p44S10
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 MOV34, P40, Rpn8, S12
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) IFI5111, MGC8628, PA28A, PA28alpha, REGalpha
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) IFI5111, MGC8628, PA28A, PA28alpha, REGalpha
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) PA28B, PA28beta, REGbeta
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) PA28B, PA28beta, REGbeta
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) Ki, PA28-gamma, PA28G, REG-GAMMA
RAET1E retinoic acid early transcript 1E LETAL, MGC125308, MGC125309, RAET1E2, ULBP4, bA350J20.7
RAET1G retinoic acid early transcript 1G ULBP5
RAET1L retinoic acid early transcript 1L -
RELB v-rel reticuloendotheliosis viral oncogene homolog B I-REL, IREL
RFX5 regulatory factor X, 5 (influences HLA class II expression) -
RFXANK regulatory factor X-associated ankyrin-containing protein ANKRA1, BLS, F14150_1, MGC138628, RFX-B
RFXAP regulatory factor X-associated protein -
SHFM1 split hand/foot malformation (ectrodactyly) type 1 DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 ASBT, ISBT, NTCP2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) ABC18, ABCB3, APT2, D6S217E, PSF2, RING11
TAPBP TAP binding protein (tapasin) NGS17, TAPA, TPN, TPSN, tapasin
TAPBPL TAP binding protein-like FLJ10143, TAPBP-R, TAPBPR
THBS1 thrombospondin 1 THBS, THBS-1, TSP, TSP-1, TSP1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein C20orf188, TRRP4AP, TRUSS
UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBS, MGC142065, MGC142067
UBXN1 UBX domain protein 1 2B28, UBXD10
ULBP1 UL16 binding protein 1 RAET1I
ULBP2 UL16 binding protein 2 N2DL2, RAET1H
ULBP3 UL16 binding protein 3 RAET1N

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BCR signaling icon BCR Signaling

B cells mediate humoral immunity through the secretion of antibodies, and also function as antigen presenting cells. B cells in secondary lymphoid organs recognize specific antigens through the B cell receptor (BCR). The strength and duration of signaling controls the fate of B cells and can lead to the formation of a high avidity BCR through repeat cycles of expansion.

Symbol Name Synonyms
AKT1 v-akt murine thymoma viral oncogene homolog 1 AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
AKT2 v-akt murine thymoma viral oncogene homolog 2 PKBB, PKBBETA, PRKBB, RAC-BETA
AKT3 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
BCL10 B-cell CLL/lymphoma 10 CARMEN, CIPER, CLAP, c-E10, mE10
BLNK B-cell linker BASH, BLNK-S, LY57, MGC111051, SLP-65, SLP65
BTK Bruton agammaglobulinemia tyrosine kinase AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA
CARD11 caspase recruitment domain family, member 11 BIMP3, CARMA1, MGC133069
CD19 CD19 molecule B4, MGC12802
CD22 CD22 molecule FLJ22814, MGC130020, SIGLEC-2, SIGLEC2
CD72 CD72 molecule CD72b, LYB2
CD79A CD79a molecule, immunoglobulin-associated alpha IGA, MB-1
CD79B CD79b molecule, immunoglobulin-associated beta B29, IGB
CD81 CD81 molecule S5.7, TAPA1, TSPAN28
CHP calcium binding protein P22 SLC9A1BP
CHP2 calcineurin B homologous protein 2 -
CHUK conserved helix-loop-helix ubiquitous kinase IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
CR2 complement component (3d/Epstein Barr virus) receptor 2 C3DR, CD21, SLEB9
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) CD32, CD32B, FCG2, FCGR2, IGFR2
FOS v-fos FBJ murine osteosarcoma viral oncogene homolog AP-1, C-FOS
GSK3B glycogen synthase kinase 3 beta -
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
IFITM1 interferon induced transmembrane protein 1 (9-27) 9-27, CD225, IFI17, LEU13
[email protected] immunoglobulin heavy locus DKFZp686C15213, IGH, [email protected], IGHDY1, MGC72071, MGC88774
IGHA1 immunoglobulin heavy constant alpha 1 FLJ14473, FLJ35065, FLJ35500, FLJ36402, FLJ39698, FLJ40001, FLJ41548, FLJ41552, FLJ41789, FLJ43248, FLJ43594, FLJ44293, FLJ46028, FLJ46621, FLJ46724, FLJ46811, FLJ46824, FLJ90170, IgA1, MGC102857
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) -
IGHD immunoglobulin heavy constant delta FLJ00382, FLJ46727, MGC29633
[email protected] immunoglobulin heavy diversity group IGD1, IGHDY1
IGHD1-1 immunoglobulin heavy diversity 1-1 IGHD11
IGHD1-14 immunoglobulin heavy diversity 1-14 (non-functional) DM2, IGHD114
IGHD1-20 immunoglobulin heavy diversity 1-20 IGHD120
IGHD1-26 immunoglobulin heavy diversity 1-26 IGHD126
IGHD1-7 immunoglobulin heavy diversity 1-7 DM1, IGHD17
IGHD2-15 immunoglobulin heavy diversity 2-15 D2, IGHD215
IGHD2-2 immunoglobulin heavy diversity 2-2 IGHD22
IGHD2-21 immunoglobulin heavy diversity 2-21 IGHD221
IGHD2-8 immunoglobulin heavy diversity 2-8 DLR1, IGHD28
IGHD3-10 immunoglobulin heavy diversity 3-10 DXP'1, IGHD310
IGHD3-16 immunoglobulin heavy diversity 3-16 IGHD316
IGHD3-22 immunoglobulin heavy diversity 3-22 IGHD322
IGHD3-3 immunoglobulin heavy diversity 3-3 DXP4, IGHD33
IGHD3-9 immunoglobulin heavy diversity 3-9 DXP1, IGHD39
IGHD4-11 immunoglobulin heavy diversity 4-11 (non-functional) DA1, IGHD411
IGHD4-17 immunoglobulin heavy diversity 4-17 IGHD417
IGHD4-23 immunoglobulin heavy diversity 4-23 (non-functional) IGHD423
IGHD4-4 immunoglobulin heavy diversity 4-4 DA4, IGHD44
IGHD5-12 immunoglobulin heavy diversity 5-12 DK1, IGHD512
IGHD5-18 immunoglobulin heavy diversity 5-18 IGHD518
IGHD5-24 immunoglobulin heavy diversity 5-24 (non-functional) IGHD524
IGHD5-5 immunoglobulin heavy diversity 5-5 DK4, IGHD55
IGHD6-13 immunoglobulin heavy diversity 6-13 DN1, IGHD613
IGHD6-19 immunoglobulin heavy diversity 6-19 IGHD619
IGHD6-25 immunoglobulin heavy diversity 6-25 IGHD625
IGHD6-6 immunoglobulin heavy diversity 6-6 D(N4), IGHD66
IGHD7-27 immunoglobulin heavy diversity 7-27 DHQ52, IGHD727
IGHE immunoglobulin heavy constant epsilon IgE
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) -
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) DKFZp686I04196
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) DKFZp686H11213, FLJ39988, FLJ40036, FLJ40253, FLJ40587, FLJ40789, FLJ40834, IgG3, MGC45809
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) MGC117419
[email protected] immunoglobulin heavy joining group IGHJ
IGHJ1 immunoglobulin heavy joining 1 JH1
IGHJ2 immunoglobulin heavy joining 2 JH2
IGHJ3 immunoglobulin heavy joining 3 JH3b
IGHJ4 immunoglobulin heavy joining 4 JH4b
IGHJ5 immunoglobulin heavy joining 5 JH5b
IGHJ6 immunoglobulin heavy joining 6 JH6b
IGHM immunoglobulin heavy constant mu DKFZp686I15196, DKFZp686I15212, FLJ00385, MGC104996, MGC52291, MU, VH
[email protected] immunoglobulin heavy variable group IGHV
IGHV1-18 immunoglobulin heavy variable 1-18 IGHV118
IGHV1-2 immunoglobulin heavy variable 1-2 IGHV12
IGHV1-24 immunoglobulin heavy variable 1-24 IGHV124, VH
IGHV1-3 immunoglobulin heavy variable 1-3 IGHV13
IGHV1-45 immunoglobulin heavy variable 1-45 IGHV145, VH
IGHV1-46 immunoglobulin heavy variable 1-46 IGHV146
IGHV1-58 immunoglobulin heavy variable 1-58 IGHV158, VH
IGHV1-69 immunoglobulin heavy variable 1-69 IGHV1-E, IGHV169, IGHV1E
IGHV1-8 immunoglobulin heavy variable 1-8 IGHV18
IGHV1-C immunoglobulin heavy variable 1-C (provisional, non-functional) IGHV1C
IGHV1-F immunoglobulin heavy variable 1-F (provisional) IGHV1F
IGHV2-26 immunoglobulin heavy variable 2-26 IGHV226, VH
IGHV2-5 immunoglobulin heavy variable 2-5 IGHV25, VH
IGHV2-70 immunoglobulin heavy variable 2-70 IGHV270, VH
IGHV3-11 immunoglobulin heavy variable 3-11 (gene/pseudogene) IGHV311, VH
IGHV3-13 immunoglobulin heavy variable 3-13 IGHV313
IGHV3-15 immunoglobulin heavy variable 3-15 IGHV315, VH
IGHV3-16 immunoglobulin heavy variable 3-16 (non-functional) IGHV316, VH
IGHV3-20 immunoglobulin heavy variable 3-20 IGHV320, VH
IGHV3-21 immunoglobulin heavy variable 3-21 IGHV321, VH
IGHV3-23 immunoglobulin heavy variable 3-23 DP47, IGHV323, V3-23, VH26
IGHV3-30 immunoglobulin heavy variable 3-30 IGHV330, VH
IGHV3-30-3 immunoglobulin heavy variable 3-30-3 IGHV3-3, IGHV3303
IGHV3-30-5 immunoglobulin heavy variable 3-30-5 IGHV3-3, IGHV3305
IGHV3-33 immunoglobulin heavy variable 3-33 IGHV333, VH
IGHV3-35 immunoglobulin heavy variable 3-35 (non-functional) IGHV335, VH
IGHV3-38 immunoglobulin heavy variable 3-38 (non-functional) IGHV338, VH
IGHV3-43 immunoglobulin heavy variable 3-43 IGHV343, VH
IGHV3-48 immunoglobulin heavy variable 3-48 IGHV348, VH
IGHV3-49 immunoglobulin heavy variable 3-49 IGHV349, VH
IGHV3-53 immunoglobulin heavy variable 3-53 IGHV353, VH
IGHV3-64 immunoglobulin heavy variable 3-64 IGHV364, VH
IGHV3-66 immunoglobulin heavy variable 3-66 IGHV366, VH
IGHV3-7 immunoglobulin heavy variable 3-7 IGHV37, VH
IGHV3-72 immunoglobulin heavy variable 3-72 IGHV372, VH
IGHV3-73 immunoglobulin heavy variable 3-73 IGHV373, VH
IGHV3-74 immunoglobulin heavy variable 3-74 IGHV374, VH
IGHV3-9 immunoglobulin heavy variable 3-9 IGHV39, VH
IGHV3-D immunoglobulin heavy variable 3-D (provisional) IGHV3D
IGHV3-H immunoglobulin heavy variable 3-H pseudogene (provisional) IGHV3H
IGHV4-28 immunoglobulin heavy variable 4-28 IGHV428, VH
IGHV4-30-1 immunoglobulin heavy variable 4-30-1 IGHV4-3
IGHV4-30-2 immunoglobulin heavy variable 4-30-2 IGHV4-3, IGHV4302
IGHV4-30-4 immunoglobulin heavy variable 4-30-4 IGHV4-3, IGHV4304
IGHV4-31 immunoglobulin heavy variable 4-31 FLJ45507, IGHV431
IGHV4-34 immunoglobulin heavy variable 4-34 IGHV434, VH
IGHV4-39 immunoglobulin heavy variable 4-39 IGHV439, VH
IGHV4-4 immunoglobulin heavy variable 4-4 IGHV44, VH
IGHV4-59 immunoglobulin heavy variable 4-59 IGHV459, VH
IGHV4-61 immunoglobulin heavy variable 4-61 IGHV461, VH
IGHV4-B immunoglobulin heavy variable 4-B (provisional) IGHV4B
IGHV5-51 immunoglobulin heavy variable 5-51 IGHV551, VH
IGHV5-A immunoglobulin heavy variable 5-A (provisional, gene/pseudogene) IGHV5A
IGHV6-1 immunoglobulin heavy variable 6-1 IGHV61, VH
IGHV7-4-1 immunoglobulin heavy variable 7-4-1 IGHV7-41, IGHV741
IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional) IGHV781
[email protected] immunoglobulin kappa locus FLJ26296, IGK, IGKC, MGC22645, MGC27376, MGC40426, MGC71990
IGKC immunoglobulin kappa constant HCAK1, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
IGKDEL immunoglobulin kappa deleting element or like IGKDE
[email protected] immunoglobulin kappa joining group IGKJ
IGKJ1 immunoglobulin kappa joining 1 J1
IGKJ2 immunoglobulin kappa joining 2 J2
IGKJ3 immunoglobulin kappa joining 3 J3
IGKJ4 immunoglobulin kappa joining 4 J4
IGKJ5 immunoglobulin kappa joining 5 J5
[email protected] immunoglobulin kappa variable group IGKV, IGKV1, [email protected], IGKV2, [email protected], IGKV3, [email protected]
IGKV1-12 immunoglobulin kappa variable 1-12 IGKV112, L19
IGKV1-13 immunoglobulin kappa variable 1-13 (gene/pseudogene) IGKV113, L18
IGKV1-16 immunoglobulin kappa variable 1-16 IGKV116, L1
IGKV1-17 immunoglobulin kappa variable 1-17 A30, IGKV117
IGKV1-27 immunoglobulin kappa variable 1-27 A20, IGKV127
IGKV1-33 immunoglobulin kappa variable 1-33 IGKV133, O18
IGKV1-37 immunoglobulin kappa variable 1-37 (non-functional) IGKV137, O14
IGKV1-39 immunoglobulin kappa variable 1-39 (gene/pseudogene) IGKV139, O12, O12a
IGKV1-5 immunoglobulin kappa variable 1-5 IGKV, IGKV15, L12, L12a, MGC22745, MGC32715, MGC88810, V1
IGKV1-6 immunoglobulin kappa variable 1-6 IGKV16, L11
IGKV1-8 immunoglobulin kappa variable 1-8 IGKV18, L9
IGKV1-9 immunoglobulin kappa variable 1-9 IGKV19, L8
IGKV1D-12 immunoglobulin kappa variable 1D-12 IGKV1D12, L19
IGKV1D-13 immunoglobulin kappa variable 1D-13 IGKV1D13, L18
IGKV1D-16 immunoglobulin kappa variable 1D-16 IGKV1D16, L15, L15a
IGKV1D-17 immunoglobulin kappa variable 1D-17 IGKV1D17, L14
IGKV1D-33 immunoglobulin kappa variable 1D-33 IGKV1D33, O8
IGKV1D-37 immunoglobulin kappa variable 1D-37 (non-functional) IGKV1D37, O4
IGKV1D-39 immunoglobulin kappa variable 1D-39 IGKV1D39, O2
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) IGKV1D42, L22
IGKV1D-43 immunoglobulin kappa variable 1D-43 IGKV1D43, L23, L23a
IGKV1D-8 immunoglobulin kappa variable 1D-8 IGKV1D8, L24, L24a
IGKV2-24 immunoglobulin kappa variable 2-24 A23, IGKV224
IGKV2-28 immunoglobulin kappa variable 2-28 A19, IGKV228
IGKV2-30 immunoglobulin kappa variable 2-30 A17, IGKV230
IGKV2-40 immunoglobulin kappa variable 2-40 IGKV240, O11, O11a
IGKV2D-24 immunoglobulin kappa variable 2D-24 (non-functional) A7, IGKV2D24
IGKV2D-28 immunoglobulin kappa variable 2D-28 A3, IGKV2D28
IGKV2D-29 immunoglobulin kappa variable 2D-29 A2a, A2c, IGKV2D29
IGKV2D-30 immunoglobulin kappa variable 2D-30 A1, IGKV2D30
IGKV2D-40 immunoglobulin kappa variable 2D-40 IGKV2D40, O1
IGKV3-11 immunoglobulin kappa variable 3-11 IGKV311, L6
IGKV3-15 immunoglobulin kappa variable 3-15 IGKV315, L2
IGKV3-20 immunoglobulin kappa variable 3-20 13K18, A27, IGKV320
IGKV3-7 immunoglobulin kappa variable 3-7 (non-functional) IGKV37, L10, L10a, Vh
IGKV3D-11 immunoglobulin kappa variable 3D-11 IGKV3D11, L20
IGKV3D-15 immunoglobulin kappa variable 3D-15 (gene/pseudogene) IGKV3D15, L16, L16a, L16b, L16c
IGKV3D-20 immunoglobulin kappa variable 3D-20 A11, A11a, IGKV3D20
IGKV3D-7 immunoglobulin kappa variable 3D-7 IGKV3D7, L25
IGKV4-1 immunoglobulin kappa variable 4-1 B3, IGKV41
IGKV5-2 immunoglobulin kappa variable 5-2 B2, IGKV52
IGKV6-21 immunoglobulin kappa variable 6-21 (non-functional) A26, IGKV621
IGKV6D-21 immunoglobulin kappa variable 6D-21 (non-functional) A10, IGKV6D21
IGKV6D-41 immunoglobulin kappa variable 6D-41 (non-functional) A14
[email protected] immunoglobulin lambda locus IGL, MGC88804
IGLC1 immunoglobulin lambda constant 1 (Mcg marker) IGLC
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker) IGLC, MGC20392, MGC45681
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker) IGLC
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene) IGLC
IGLC7 immunoglobulin lambda constant 7 C7
[email protected] immunoglobulin lambda joining group IGLJ
IGLJ1 immunoglobulin lambda joining 1 J1
IGLJ2 immunoglobulin lambda joining 2 J2
IGLJ3 immunoglobulin lambda joining 3 J3
IGLJ4 immunoglobulin lambda joining 4 (non-functional) -
IGLJ5 immunoglobulin lambda joining 5 (non-functional) -
IGLJ6 immunoglobulin lambda joining 6 -
IGLJ7 immunoglobulin lambda joining 7 J7
[email protected] immunoglobulin lambda variable group IGLV
IGLV1-36 immunoglobulin lambda variable 1-36 IGLV136, V1-11
IGLV1-40 immunoglobulin lambda variable 1-40 IGLV140, V1-13
IGLV1-44 immunoglobulin lambda variable 1-44 IGLV144, V1-16
IGLV1-47 immunoglobulin lambda variable 1-47 IGLV147, V1-17
IGLV1-50 immunoglobulin lambda variable 1-50 (non-functional) IGLV150, V1-18
IGLV1-51 immunoglobulin lambda variable 1-51 IGLV151, V1-19
IGLV10-54 immunoglobulin lambda variable 10-54 IGLV1054, V1-20
IGLV11-55 immunoglobulin lambda variable 11-55 (non-functional) IGLV1155, V4-6
IGLV2-11 immunoglobulin lambda variable 2-11 IGLV211, V1-3
IGLV2-14 immunoglobulin lambda variable 2-14 IGLV214, V1-4
IGLV2-18 immunoglobulin lambda variable 2-18 IGLV218, V1-5
IGLV2-23 immunoglobulin lambda variable 2-23 IGLV223, V1-7
IGLV2-33 immunoglobulin lambda variable 2-33 (non-functional) IGLV233, V1-9
IGLV2-8 immunoglobulin lambda variable 2-8 IGLV28, V1-2
IGLV3-1 immunoglobulin lambda variable 3-1 IGLV31, V2-1
IGLV3-10 immunoglobulin lambda variable 3-10 IGLV310, V2-7
IGLV3-12 immunoglobulin lambda variable 3-12 IGLV312, V2-8
IGLV3-16 immunoglobulin lambda variable 3-16 IGLV316, V2-11
IGLV3-19 immunoglobulin lambda variable 3-19 IGLV319, V2-13, VL3L
IGLV3-21 immunoglobulin lambda variable 3-21 IGLV321, V2-14
IGLV3-22 immunoglobulin lambda variable 3-22 (gene/pseudogene) IGLV322, V2-15
IGLV3-25 immunoglobulin lambda variable 3-25 IGLV325, MGC105005, V2-17
IGLV3-27 immunoglobulin lambda variable 3-27 IGLV327, V2-19
IGLV3-32 immunoglobulin lambda variable 3-32 (non-functional) IGLV332, V2-23P
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) IGLV39, V2-6
IGLV4-3 immunoglobulin lambda variable 4-3 IGLV43, V5-1
IGLV4-60 immunoglobulin lambda variable 4-60 IGLV460, V5-4
IGLV4-69 immunoglobulin lambda variable 4-69 IGLV469, V5-6
IGLV5-37 immunoglobulin lambda variable 5-37 IGLV537, V4-1
IGLV5-39 immunoglobulin lambda variable 5-39 IGLV539
IGLV5-45 immunoglobulin lambda variable 5-45 IGLV545, V4-2
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) IGLV548, V4-3
IGLV5-52 immunoglobulin lambda variable 5-52 IGLV552, V4-4
IGLV6-57 immunoglobulin lambda variable 6-57 IGLV657, MGC34845, V1-22
IGLV7-43 immunoglobulin lambda variable 7-43 IGLV743, V3-2
IGLV7-46 immunoglobulin lambda variable 7-46 (gene/pseudogene) IGLV746, V3-3
IGLV8-61 immunoglobulin lambda variable 8-61 IGLV861, V3-4
IGLV9-49 immunoglobulin lambda variable 9-49 IGLV949, V5-2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta FLJ40509, IKK-beta, IKK2, IKKB, MGC131801, NFKBIKB
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO
INPP5D inositol polyphosphate-5-phosphatase, 145kDa MGC104855, MGC142140, MGC142142, SHIP, SHIP1, SIP-145, hp51CN
JUN jun oncogene AP-1, AP1, c-Jun
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 CD85A, HL9, ILT5, LIR-3, LIR3, MGC138403, PIRB
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog FLJ26625, JTK8
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 DKFZp434L132, MLT, MLT1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 MGC138448, NF-ATC, NFAT2, NFATc
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 NFAT1, NFATP
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFAT4, NFATX
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 NF-ATc4, NFAT3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 DKFZp686C01211, EBP-1, KBF1, MGC54151, NF-kappa-B, NFKB-p105, NFKB-p50, p105, p50
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha IKBA, MAD-3, NFKBI
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta IKBB, TRIP9
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon IKBE
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog ALPS4, N-ras, NRAS1
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide MGC142161, MGC142163, PI3K, p110-alpha
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA
PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide p110D
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide PI3CG, PI3K, PI3Kgamma, PIK3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GRB1, p85, p85-ALPHA
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) P85B, p85, p85-BETA
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) DKFZp686P05226, FLJ41892, p55, p55-GAMMA
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 F730038I15Rik, FOAP-2, P101-PI3K, p101
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -
PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B
PPP3CB protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform CALNA2, CALNB
PPP3CC protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform CALNA3
PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform CALNB1, CNB, CNB1
PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform PPP3RL
PRKCB protein kinase C, beta MGC41878, PKC-beta, PKCB, PRKCB1, PRKCB2
PTPN6 protein tyrosine phosphatase, non-receptor type 6 HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) MGC111543, MIG5, TC-25, p21-Rac1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) EN-7, Gx, HSPC022
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) GRP3, KIAA0846
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) MGC131774, NFKB3, p65
SYK spleen tyrosine kinase DKFZp313N1010, FLJ25043, FLJ37489
VAV1 vav 1 guanine nucleotide exchange factor VAV
VAV2 vav 2 guanine nucleotide exchange factor -
VAV3 vav 3 guanine nucleotide exchange factor FLJ40431

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Chemokines Icon Chemokines

Chemokines, or chemotactic cytokines, are small proteins that can be secreted by immune cells and other cell types. They can be grouped in to the CC, CXC, XC, and CX3C families based on conserved cysteine residues. Chemokines recruit innate and adaptive immune cells to sites of inflammation throughout the body.

Symbol Name Synonyms
C3 complement component 3 ARMD9, ASP, CPAMD1
C5 complement component 5 CPAMD4, FLJ17816, FLJ17822, MGC142298
C5AR1 complement component 5a receptor 1 C5A, C5AR, C5R1, CD88
CAMP cathelicidin antimicrobial peptide CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37
CCBP2 chemokine binding protein 2 CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6
CCL1 chemokine (C-C motif) ligand 1 I-309, P500, SCYA1, SISe, TCA3
CCL11 chemokine (C-C motif) ligand 11 MGC22554, SCYA11
CCL13 chemokine (C-C motif) ligand 13 CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1
CCL14 chemokine (C-C motif) ligand 14 CC-1, CC-3, CKb1, FLJ16015, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14
CCL14-CCL15 chemokine ligand 14, chemokine ligand 15 transcription unit -
CCL15 chemokine (C-C motif) ligand 15 HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15
CCL16 chemokine (C-C motif) ligand 16 CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4
CCL17 chemokine (C-C motif) ligand 17 A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
CCL19 chemokine (C-C motif) ligand 19 CKb11, ELC, MGC34433, MIP-3b, MIP3B, SCYA19
CCL2 chemokine (C-C motif) ligand 2 GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
CCL20 chemokine (C-C motif) ligand 20 CKb4, LARC, MIP-3a, MIP3A, SCYA20, ST38
CCL21 chemokine (C-C motif) ligand 21 6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4
CCL22 chemokine (C-C motif) ligand 22 A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1
CCL23 chemokine (C-C motif) ligand 23 CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23
CCL24 chemokine (C-C motif) ligand 24 Ckb-6, MPIF-2, MPIF2, SCYA24
CCL25 chemokine (C-C motif) ligand 25 Ckb15, MGC150327, SCYA25, TECK
CCL26 chemokine (C-C motif) ligand 26 IMAC, MGC126714, MIP-4a, MIP-4alpha, SCYA26, TSC-1
CCL27 chemokine (C-C motif) ligand 27 ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
CCL28 chemokine (C-C motif) ligand 28 CCK1, MEC, MGC71902, SCYA28
CCL3 chemokine (C-C motif) ligand 3 G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
CCL3L1 chemokine (C-C motif) ligand 3-like 1 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MGC104178, MGC12815, MGC182017, MIP1AP, SCYA3L, SCYA3L1
CCL3L2 chemokine (C-C motif) ligand 3-like 2 G0S19-3, LD78gamma, SCYA3L2
CCL3L3 chemokine (C-C motif) ligand 3-like 3 464.2, D17S1718, LD78, LD78BETA, MGC12815, SCYA3L, SCYA3L1
CCL4 chemokine (C-C motif) ligand 4 ACT2, AT744.1, G-26, LAG1, MGC104418, MGC126025, MGC126026, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
CCL4L1 chemokine (C-C motif) ligand 4-like 1 AT744.2, CCL4L, LAG-1, LAG1, SCYA4L
CCL4L2 chemokine (C-C motif) ligand 4-like 2 AT744.2, CCL4L, SCYA4L
CCL5 chemokine (C-C motif) ligand 5 D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
CCL7 chemokine (C-C motif) ligand 7 FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7
CCL8 chemokine (C-C motif) ligand 8 HC14, MCP-2, MCP2, SCYA10, SCYA8
CCR1 chemokine (C-C motif) receptor 1 CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
CCR10 chemokine (C-C motif) receptor 10 GPR2
CCR3 chemokine (C-C motif) receptor 3 CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
CCR4 chemokine (C-C motif) receptor 4 CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293
CCR5 chemokine (C-C motif) receptor 5 CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, FLJ78003, IDDM22
CCR6 chemokine (C-C motif) receptor 6 BN-1, CD196, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22
CCR7 chemokine (C-C motif) receptor 7 BLR2, CD197, CDw197, CMKBR7, EBI1
CCR8 chemokine (C-C motif) receptor 8 CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1
CCR9 chemokine (C-C motif) receptor 9 CDw199, GPR-9-6, GPR28
CCRL1 chemokine (C-C motif) receptor-like 1 CC-CKR-11, CCBP2, CCR10, CCR11, CCX-CKR, CKR-11, PPR1, VSHK1
CCRL2 chemokine (C-C motif) receptor-like 2 CKRX, CRAM-A, CRAM-B, FLJ55815, HCR, MGC116710, MGC34104
CKLF chemokine-like factor C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1
CMA1 chymase 1, mast cell CYH, MCT1, MGC119890, MGC119891, chymase
CMKLR1 chemokine-like receptor 1 CHEMERINR, ChemR23, DEZ, MGC126105, MGC126106
CTSG cathepsin G CG, MGC23078
CX3CL1 chemokine (C-X3-C motif) ligand 1 ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin
CX3CR1 chemokine (C-X3-C motif) receptor 1 CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
CXCL10 chemokine (C-X-C motif) ligand 10 C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
CXCL11 chemokine (C-X-C motif) ligand 11 H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1
CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1
CXCL13 chemokine (C-X-C motif) ligand 13 ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
CXCL14 chemokine (C-X-C motif) ligand 14 BMAC, BRAK, KS1, Kec, MGC10687, MIP-2g, NJAC, SCYB14, bolekine
CXCL16 chemokine (C-X-C motif) ligand 16 CXCLG16, SR-PSOX, SRPSOX
CXCL17 chemokine (C-X-C motif) ligand 17 DMC, Dcip1, MGC138300, UNQ473, VCC-1, VCC1
CXCL2 chemokine (C-X-C motif) ligand 2 CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2
CXCL3 chemokine (C-X-C motif) ligand 3 CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3
CXCL5 chemokine (C-X-C motif) ligand 5 ENA-78, SCYB5
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) CKA-3, GCP-2, GCP2, SCYB6
CXCL9 chemokine (C-X-C motif) ligand 9 CMK, Humig, MIG, SCYB9, crg-10
CXCR3 chemokine (C-X-C motif) receptor 3 CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR
CXCR4 chemokine (C-X-C motif) receptor 4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
CXCR5 chemokine (C-X-C motif) receptor 5 BLR1, CD185, MDR15, MGC117347
CXCR6 chemokine (C-X-C motif) receptor 6 BONZO, CD186, STRL33, TYMSTR
CXCR7 chemokine (C-X-C motif) receptor 7 CMKOR1, GPR159, RDC1
CYR61 cysteine-rich, angiogenic inducer, 61 CCN1, GIG1, IGFBP10
CYSLTR1 cysteinyl leukotriene receptor 1 CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
CYSLTR2 cysteinyl leukotriene receptor 2 CYSLT2, CYSLT2R, GPCR, HG57, HPN321, KPG_011, PSEC0146, hGPCR21
DARC Duffy blood group, chemokine receptor CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1
DEFA1 defensin, alpha 1 DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS
DEFA3 defensin, alpha 3, neutrophil-specific DEF3, HNP-3, HNP3, HP-3
DEFA5 defensin, alpha 5, Paneth cell-specific DEF5, HD-5, MGC129728
DEFB1 defensin, beta 1 BD1, DEFB-1, DEFB101, HBD1, MGC51822
DEFB103A defensin, beta 103A DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3
DEFB104A defensin, beta 104A BD-4, DEFB-4, DEFB104, DEFB4, MGC118942, MGC118944, MGC118945, hBD-4
DEFB4 defensin, beta 4 DEFB-2, DEFB102, DEFB2, HBD-2, SAP1
EDN1 endothelin 1 ET1, HDLCQ7
EDN2 endothelin 2 ET2, PPET2
EDN3 endothelin 3 ET3, MGC15067, MGC61498
EDNRA endothelin receptor type A ETA, ETRA
EDNRB endothelin receptor type B ABCDS, ETB, ETBR, ETRB, HSCR, HSCR2
FGF10 fibroblast growth factor 10 -
FGF2 fibroblast growth factor 2 (basic) BFGF, FGFB, HBGF-2
FPR1 formyl peptide receptor 1 FMLP, FPR
FPR2 formyl peptide receptor 2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
FPR2 formyl peptide receptor 2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
GPR17 G protein-coupled receptor 17 DKFZp686M18273
GPR32 G protein-coupled receptor 32 -
GPR33 G protein-coupled receptor 33 (gene/pseudogene) -
GPR44 G protein-coupled receptor 44 CD294, CRTH2, DP2
GPR77 G protein-coupled receptor 77 C5L2, GPF77
HTN3 histatin 3 HIS2, HTN2, HTN5
IL8 interleukin 8 CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
IL8RA interleukin 8 receptor, alpha C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA
IL8RB interleukin 8 receptor, beta CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA
LECT2 leukocyte cell-derived chemotaxin 2 MGC126628, chm-II, chm2
LTB4R leukotriene B4 receptor BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
LTB4R2 leukotriene B4 receptor 2 BLT2, BLTR2, JULF2, KPG_004, NOP9
PF4 platelet factor 4 CXCL4, MGC138298, SCYB4
PF4V1 platelet factor 4 variant 1 CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1
PLAU plasminogen activator, urokinase ATF, UPA, URK, u-PA
PLAUR plasminogen activator, urokinase receptor CD87, UPAR, URKR
PLXNA1 plexin A1 NOV, NOVP, PLEXIN-A1, PLXN1
PLXNA2 plexin A2 FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
PLXNA3 plexin A3 6.3, HSSEXGENE, PLEXIN-A3, PLXN3, PLXN4, SEX, XAP-6
PLXNA4 plexin A4 DKFZp434G0625, DKFZp566O0546, FAYV2820, FLJ35026, FLJ38287, KIAA1550, PLEXA4, PLXNA4A, PLXNA4B, PRO34003
PLXNB1 plexin B1 KIAA0407, MGC149167, PLEXIN-B1, PLXN5, SEP
PLXNB2 plexin B2 KIAA0315, MM1, Nbla00445, PLEXB2, dJ402G11.3
PLXNB3 plexin B3 FLJ76953, PLEXB3, PLEXR, PLXN6
PLXNC1 plexin C1 CD232, PLXN-C1, VESPR
PLXND1 plexin D1 KIAA0620, MGC75353, PLEXD1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
PPBPL1 pro-platelet basic protein-like 1 TGB2
PROK2 prokineticin 2 BV8, KAL4, MIT1, PK2
PTAFR platelet-activating factor receptor PAFR
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) EDN, RNS2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) DUTT1, FLJ21882, MGC131599, MGC133277, SAX3
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) KIAA1568, SAX3
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) FLJ21044, HGPPS, HGPS, RBIG1, RIG1
RXFP3 relaxin/insulin-like family peptide receptor 3 GPCR135, MGC141998, MGC142000, RLN3R1, RXFPR3, SALPR
SAA1 serum amyloid A1 MGC111216, PIG4, SAA, TP53I4
SAA2 serum amyloid A2 -
SBDS Shwachman-Bodian-Diamond syndrome CGI-97, FLJ10917, SDS, SWDS
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B FLJ34863, LUCA-1, SEMA5, SEMAA, SemA, semaV
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C SEMAE, SemE
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D MGC39708, Sema-Z2, coll-2
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E KIAA0331, M-SEMAH, M-SemaK, SEMAH, coll-5
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F SEMA-IV, SEMA4, SEMAK
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G FLJ00014, MGC119473, sem2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A CORD10, FLJ12287, RP35, SEMAB, SEMB
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B KIAA1745, MGC131831, SEMAC, SemC
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C FLJ20369, KIAA1739, M-SEMA-F, MGC126382, MGC126383, SEMACL1, SEMAF, SEMAI
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D C9orf164, CD100, FLJ33485, FLJ34282, FLJ39737, FLJ46484, M-sema-G, MGC169138, MGC169141, SEMAJ, coll-4
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F M-SEMA, PRO2353, SEMAM, SEMAW, m-Sema-M
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G FLJ20590, KIAA1619, MGC102867
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A FLJ12815, SEMAF, semF
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B FLJ10372, KIAA1445, SEMAG, SemG
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ, VIA
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C SEMAY, m-SemaY, m-SemaY2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D FLJ11598, KIAA1479
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, MGC126696, SEMAK1, SEMAL
SLIT1 slit homolog 1 (Drosophila) MEGF4, MGC164811, SLIL1, SLIT3, Slit-1
SLIT2 slit homolog 2 (Drosophila) FLJ14420, SLIL3, Slit-2
TNC tenascin C HXB, MGC167029, TN
TYMP thymidine phosphorylase ECGF1, MNGIE, PDECGF, TP, hPD-ECGF
XCL1 chemokine (C motif) ligand 1 ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1
XCL2 chemokine (C motif) ligand 2 SCM-1b, SCM1B, SCYC2
XCR1 chemokine (C motif) receptor 1 CCXCR1, GPR5

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Cytokines Icon Cytokines

Cytokines are molecules that enable cells of the immune system to communicate with each other across long distances. During infection and inflammation, the different cytokines that are released tailor the immune response to a specific trigger.

Symbol Name Synonyms
ACVR1B activin A receptor, type IB ACTRIB, ACVRLK4, ALK4, SKR2
ACVR1C activin A receptor, type IC ACVRLK7, ALK7
ACVR2A activin A receptor, type IIA ACTRII, ACVR2
ACVR2B activin A receptor, type IIB ACTRIIB, ActR-IIB, MGC116908
ACVRL1 activin A receptor type II-like 1 ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I PAC1, PACAPR, PACAPRI
ADIPOQ adiponectin, C1Q and collagen domain containing ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28, adiponectin
ADIPOR1 adiponectin receptor 1 ACDCR1, CGI-45, CGI45, FLJ25385, FLJ42464, PAQR1, TESBP1A
ADIPOR2 adiponectin receptor 2 ACDCR2, FLJ21432, MGC4640, PAQR2
ADM adrenomedullin AM
ADM2 adrenomedullin 2 AM2, FLJ21135, dJ579N16.4
ADRB1 adrenergic, beta-1-, receptor ADRB1R, B1AR, BETA1AR, RHR
ADRB2 adrenergic, beta-2-, receptor, surface ADRB2R, ADRBR, B2AR, BAR, BETA2AR
AGRP agouti related protein homolog (mouse) AGRT, ART, ASIP2, MGC118963
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ANHU, FLJ92595, FLJ97926, SERPINA8
AGTR1 angiotensin II receptor, type 1 AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
AGTR2 angiotensin II receptor, type 2 AT2, ATGR2, MRX88
AMBN ameloblastin (enamel matrix protein) -
AMELX amelogenin (amelogenesis imperfecta 1, X-linked) AIH1, ALGN, AMG, AMGL, AMGX
AMH anti-Mullerian hormone MIF, MIS
AMHR2 anti-Mullerian hormone receptor, type II AMHR, MISR2, MISRII
ANGPT1 angiopoietin 1 AGP1, AGPT, ANG1
ANGPT4 angiopoietin 4 AGP4, ANG-3, ANG4, MGC138181, MGC138183
ANGPTL1 angiopoietin-like 1 ANG3, ANGPT3, ARP1, AngY, KIAA0351, UNQ162, dJ595C2.2
ANGPTL2 angiopoietin-like 2 ARP2, HARP, MGC8889
ANGPTL3 angiopoietin-like 3 ANGPT5
ANGPTL4 angiopoietin-like 4 ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158
ANGPTL5 angiopoietin-like 5 -
ANGPTL6 angiopoietin-like 6 AGF, ARP5
ANGPTL7 angiopoietin-like 7 AngX, CDT6, RP4-647M16.2, dJ647M16.1
APLN apelin XNPEP2
APLNR apelin receptor AGTRL1, APJ, APJR, FLJ90771, MGC45246
AR androgen receptor AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
AREG amphiregulin AR, CRDGF, MGC13647, SDGF
ARMET arginine-rich, mutated in early stage tumors ARP, MANF, MGC142148, MGC142150
ARMETL1 arginine-rich, mutated in early stage tumors-like 1 cdnf
ARTN artemin ENOVIN, EVN, NBN
AVP arginine vasopressin ADH, ARVP, AVP-NPII, AVRP, VP
AVPR1A arginine vasopressin receptor 1A AVPR1
AVPR1B arginine vasopressin receptor 1B AVPR3
AVPR2 arginine vasopressin receptor 2 ADHR, DI1, DIR, DIR3, MGC126533, MGC138386, NDI, V2R
AZU1 azurocidin 1 AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC
BDNF brain-derived neurotrophic factor MGC34632
BMP1 bone morphogenetic protein 1 FLJ44432, PCOLC, PCP, TLD, pCP-2
BMP10 bone morphogenetic protein 10 MGC126783
BMP15 bone morphogenetic protein 15 GDF9B, ODG2, POF4
BMP2 bone morphogenetic protein 2 BMP2A
BMP3 bone morphogenetic protein 3 BMP-3A
BMP4 bone morphogenetic protein 4 BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
BMP5 bone morphogenetic protein 5 MGC34244
BMP6 bone morphogenetic protein 6 VGR, VGR1
BMP7 bone morphogenetic protein 7 OP-1
BMP8A bone morphogenetic protein 8a FLJ14351, FLJ45264
BMP8B bone morphogenetic protein 8b BMP8, MGC131757, OP2
BMPR1A bone morphogenetic protein receptor, type IA 10q23del, ACVRLK3, ALK3, CD292, SKR5
BMPR1B bone morphogenetic protein receptor, type IB ALK-6, ALK6, CDw293
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK
BRD8 bromodomain containing 8 SMAP, SMAP2, p120
BTC betacellulin -
C19orf10 chromosome 19 open reading frame 10 EUROIMAGE1875335, IL25, IL27, IL27w, R33729_1, SF20
C3 complement component 3 ARMD9, ASP, CPAMD1
C3AR1 complement component 3a receptor 1 AZ3B, C3AR, HNFAG09
C5 complement component 5 CPAMD4, FLJ17816, FLJ17822, MGC142298
C5AR1 complement component 5a receptor 1 C5A, C5AR, C5R1, CD88
CALCA calcitonin-related polypeptide alpha CALC1, CGRP, CGRP-I, CGRP1, CT, KC, MGC126648
CALCB calcitonin-related polypeptide beta CALC2, CGRP-II, CGRP2, FLJ30166
CALCR calcitonin receptor CRT, CTR, CTR1
CALCRL calcitonin receptor-like CGRPR, CRLR
CAMP cathelicidin antimicrobial peptide CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37
CAT catalase MGC138422, MGC138424
CCBP2 chemokine binding protein 2 CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6
CCK cholecystokinin MGC117187
CCL1 chemokine (C-C motif) ligand 1 I-309, P500, SCYA1, SISe, TCA3
CCL11 chemokine (C-C motif) ligand 11 MGC22554, SCYA11
CCL13 chemokine (C-C motif) ligand 13 CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1
CCL14 chemokine (C-C motif) ligand 14 CC-1, CC-3, CKb1, FLJ16015, HCC-1, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14
CCL14-CCL15 chemokine ligand 14, chemokine ligand 15 transcription unit -
CCL15 chemokine (C-C motif) ligand 15 HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15
CCL16 chemokine (C-C motif) ligand 16 CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4
CCL17 chemokine (C-C motif) ligand 17 A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
CCL19 chemokine (C-C motif) ligand 19 CKb11, ELC, MGC34433, MIP-3b, MIP3B, SCYA19
CCL2 chemokine (C-C motif) ligand 2 GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
CCL20 chemokine (C-C motif) ligand 20 CKb4, LARC, MIP-3a, MIP3A, SCYA20, ST38
CCL21 chemokine (C-C motif) ligand 21 6Ckine, CKb9, ECL, MGC34555, SCYA21, SLC, TCA4
CCL22 chemokine (C-C motif) ligand 22 A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1
CCL23 chemokine (C-C motif) ligand 23 CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23
CCL24 chemokine (C-C motif) ligand 24 Ckb-6, MPIF-2, MPIF2, SCYA24
CCL25 chemokine (C-C motif) ligand 25 Ckb15, MGC150327, SCYA25, TECK
CCL26 chemokine (C-C motif) ligand 26 IMAC, MGC126714, MIP-4a, MIP-4alpha, SCYA26, TSC-1
CCL27 chemokine (C-C motif) ligand 27 ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
CCL28 chemokine (C-C motif) ligand 28 CCK1, MEC, MGC71902, SCYA28
CCL3 chemokine (C-C motif) ligand 3 G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3
CCL3L1 chemokine (C-C motif) ligand 3-like 1 464.2, D17S1718, G0S19-2, LD78, LD78BETA, MGC104178, MGC12815, MGC182017, MIP1AP, SCYA3L, SCYA3L1
CCL3L2 chemokine (C-C motif) ligand 3-like 2 G0S19-3, LD78gamma, SCYA3L2
CCL3L3 chemokine (C-C motif) ligand 3-like 3 464.2, D17S1718, LD78, LD78BETA, MGC12815, SCYA3L, SCYA3L1
CCL4 chemokine (C-C motif) ligand 4 ACT2, AT744.1, G-26, LAG1, MGC104418, MGC126025, MGC126026, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
CCL4L1 chemokine (C-C motif) ligand 4-like 1 AT744.2, CCL4L, LAG-1, LAG1, SCYA4L
CCL4L2 chemokine (C-C motif) ligand 4-like 2 AT744.2, CCL4L, SCYA4L
CCL5 chemokine (C-C motif) ligand 5 D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
CCL7 chemokine (C-C motif) ligand 7 FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7
CCL8 chemokine (C-C motif) ligand 8 HC14, MCP-2, MCP2, SCYA10, SCYA8
CCR1 chemokine (C-C motif) receptor 1 CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
CCR10 chemokine (C-C motif) receptor 10 GPR2
CCR3 chemokine (C-C motif) receptor 3 CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
CCR4 chemokine (C-C motif) receptor 4 CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293
CCR5 chemokine (C-C motif) receptor 5 CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, FLJ78003, IDDM22
CCR6 chemokine (C-C motif) receptor 6 BN-1, CD196, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22
CCR7 chemokine (C-C motif) receptor 7 BLR2, CD197, CDw197, CMKBR7, EBI1
CCR8 chemokine (C-C motif) receptor 8 CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1
CCR9 chemokine (C-C motif) receptor 9 CDw199, GPR-9-6, GPR28
CCRL1 chemokine (C-C motif) receptor-like 1 CC-CKR-11, CCBP2, CCR10, CCR11, CCX-CKR, CKR-11, PPR1, VSHK1
CCRL2 chemokine (C-C motif) receptor-like 2 CKRX, CRAM-A, CRAM-B, FLJ55815, HCR, MGC116710, MGC34104
CD320 CD320 molecule 8D6, 8D6A
CD40 CD40 molecule, TNF receptor superfamily member 5 Bp50, CDW40, MGC9013, TNFRSF5, p50
CD40LG CD40 ligand CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L
CD70 CD70 molecule CD27L, CD27LG, TNFSF7
CECR1 cat eye syndrome chromosome region, candidate 1 ADGF, IDGFL
CER1 cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) DAND4, MGC119894, MGC119895, MGC96951
CGA glycoprotein hormones, alpha polypeptide CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA
CGB chorionic gonadotropin, beta polypeptide CGB3, hCGB
CGB1 chorionic gonadotropin, beta polypeptide 1 -
CGB2 chorionic gonadotropin, beta polypeptide 2 -
CGB5 chorionic gonadotropin, beta polypeptide 5 HCG, MGC119822
CGB7 chorionic gonadotropin, beta polypeptide 7 CG-beta-a, FLJ35403, FLJ43118
CGB8 chorionic gonadotropin, beta polypeptide 8 -
CHGA chromogranin A (parathyroid secretory protein 1) CGA
CHGB chromogranin B (secretogranin 1) SCG1
CKLF chemokine-like factor C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1
CLCF1 cardiotrophin-like cytokine factor 1 BSF3, CISS2, CLC, NNT1, NR6
CLEC11A C-type lectin domain family 11, member A CLECSF3, LSLCL, P47, SCGF
CMA1 chymase 1, mast cell CYH, MCT1, MGC119890, MGC119891, chymase
CMKLR1 chemokine-like receptor 1 CHEMERINR, ChemR23, DEZ, MGC126105, MGC126106
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 CKLFH, CKLFH1, CKLFSF1, MGC71870
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 CKLFSF2, MGC39436
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 BNAS2, CKLFSF3, FLJ31762, MGC51956
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 CKLFSF4
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 CKLFSF5, FLJ37521
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 CKLFSF6, FLJ20396, PRO2219
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 CKLFSF7, FLJ30992
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 CKLFSF8, CKLFSF8-V2
CNTF ciliary neurotrophic factor HCNTF
CNTFR ciliary neurotrophic factor receptor MGC1774
CORT cortistatin CST-14, CST-17, CST-29
CRH corticotropin releasing hormone CRF
CRHR1 corticotropin releasing hormone receptor 1 CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f
CRHR2 corticotropin releasing hormone receptor 2 CRFR2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) MGC138194, S52
CRLF1 cytokine receptor-like factor 1 CISS, CISS1, CLF, CLF-1, NR6
CRLF2 cytokine receptor-like factor 2 CRL2, CRLF2Y, TSLPR
CRLF3 cytokine receptor-like factor 3 CREME9, CYTOR4, FRWS, MGC20661
CSF1 colony stimulating factor 1 (macrophage) MCSF, MGC31930
CSF1R colony stimulating factor 1 receptor C-FMS, CD115, CSFR, FIM2, FMS
CSF2 colony stimulating factor 2 (granulocyte-macrophage) GMCSF, MGC131935, MGC138897
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, MGC3848, MGC4838
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) CD131, CDw131, IL3RB, IL5RB
CSF3 colony stimulating factor 3 (granulocyte) G-CSF, GCSF, MGC45931
CSF3R colony stimulating factor 3 receptor (granulocyte) CD114, GCSFR
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) CSA, CSMT, FLJ75407, PL
CSH2 chorionic somatomammotropin hormone 2 CS-2, CSB, hCS-B
CSHL1 chorionic somatomammotropin hormone-like 1 CS-5, CSHP1, CSL, MGC149868, hCS-L
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) MGC44034, NGC
CTF1 cardiotrophin 1 CT-1, CT1
CTGF connective tissue growth factor CCN2, HCS24, IGFBP8, MGC102839, NOV2
CTSG cathepsin G CG, MGC23078
CX3CL1 chemokine (C-X3-C motif) ligand 1 ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin
CX3CR1 chemokine (C-X3-C motif) receptor 1 CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
CXCL10 chemokine (C-X-C motif) ligand 10 C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
CXCL11 chemokine (C-X-C motif) ligand 11 H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1
CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1
CXCL13 chemokine (C-X-C motif) ligand 13 ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
CXCL14 chemokine (C-X-C motif) ligand 14 BMAC, BRAK, KS1, Kec, MGC10687, MIP-2g, NJAC, SCYB14, bolekine
CXCL16 chemokine (C-X-C motif) ligand 16 CXCLG16, SR-PSOX, SRPSOX
CXCL17 chemokine (C-X-C motif) ligand 17 DMC, Dcip1, MGC138300, UNQ473, VCC-1, VCC1
CXCL2 chemokine (C-X-C motif) ligand 2 CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2
CXCL3 chemokine (C-X-C motif) ligand 3 CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3
CXCL5 chemokine (C-X-C motif) ligand 5 ENA-78, SCYB5
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) CKA-3, GCP-2, GCP2, SCYB6
CXCL9 chemokine (C-X-C motif) ligand 9 CMK, Humig, MIG, SCYB9, crg-10
CXCR3 chemokine (C-X-C motif) receptor 3 CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR
CXCR4 chemokine (C-X-C motif) receptor 4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
CXCR5 chemokine (C-X-C motif) receptor 5 BLR1, CD185, MDR15, MGC117347
CXCR6 chemokine (C-X-C motif) receptor 6 BONZO, CD186, STRL33, TYMSTR
CXCR7 chemokine (C-X-C motif) receptor 7 CMKOR1, GPR159, RDC1
CYR61 cysteine-rich, angiogenic inducer, 61 CCN1, GIG1, IGFBP10
CYSLTR1 cysteinyl leukotriene receptor 1 CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
CYSLTR2 cysteinyl leukotriene receptor 2 CYSLT2, CYSLT2R, GPCR, HG57, HPN321, KPG_011, PSEC0146, hGPCR21
DARC Duffy blood group, chemokine receptor CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1
DEFA1 defensin, alpha 1 DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS
DEFA3 defensin, alpha 3, neutrophil-specific DEF3, HNP-3, HNP3, HP-3
DEFA5 defensin, alpha 5, Paneth cell-specific DEF5, HD-5, MGC129728
DEFB1 defensin, beta 1 BD1, DEFB-1, DEFB101, HBD1, MGC51822
DEFB103A defensin, beta 103A DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3
DEFB104A defensin, beta 104A BD-4, DEFB-4, DEFB104, DEFB4, MGC118942, MGC118944, MGC118945, hBD-4
DEFB4 defensin, beta 4 DEFB-2, DEFB102, DEFB2, HBD-2, SAP1
DKK1 dickkopf homolog 1 (Xenopus laevis) DKK-1, SK
EBI3 Epstein-Barr virus induced 3 IL27B
EDN1 endothelin 1 ET1, HDLCQ7
EDN2 endothelin 2 ET2, PPET2
EDN3 endothelin 3 ET3, MGC15067, MGC61498
EDNRA endothelin receptor type A ETA, ETRA
EDNRB endothelin receptor type B ABCDS, ETB, ETBR, ETRB, HSCR, HSCR2
EGF epidermal growth factor (beta-urogastrone) HOMG4, URG
EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) ERBB, ERBB1, HER1, PIG61, mENA
ENG endoglin CD105, END, FLJ41744, HHT1, ORW, ORW1
EPGN epithelial mitogen homolog (mouse) ALGV3072, EPG, FLJ75542, PRO9904, epigen
EPO erythropoietin EP, MGC138142, MVCD2
EPOR erythropoietin receptor MGC138358
EREG epiregulin ER
ESM1 endothelial cell-specific molecule 1 endocan
ESR1 estrogen receptor 1 DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
ESR2 estrogen receptor 2 (ER beta) ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
ESRRA estrogen-related receptor alpha ERR1, ERRa, ERRalpha, ESRL1, NR3B1
ESRRB estrogen-related receptor beta DFNB35, ERR2, ERRb, ERRbeta, ERRbeta-2, ESRL2, NR3B2
ESRRG estrogen-related receptor gamma DKFZp781L1617, ERR3, FLJ16023, KIAA0832, NR3B3
FAM3B family with sequence similarity 3, member B 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44
FAM3C family with sequence similarity 3, member C GS3786, ILEI
FAM3D family with sequence similarity 3, member D EF7, OIT1
FASLG Fas ligand (TNF superfamily, member 6) APT1LG1, CD178, CD95L, FASL, TNFSF6
FGF1 fibroblast growth factor 1 (acidic) AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1
FGF10 fibroblast growth factor 10 -
FGF11 fibroblast growth factor 11 FHF3, FLJ16061, MGC102953, MGC45269
FGF12 fibroblast growth factor 12 FGF12B, FHF1
FGF13 fibroblast growth factor 13 FGF2, FHF-2, FHF2
FGF14 fibroblast growth factor 14 FHF4, MGC119129, SCA27
FGF16 fibroblast growth factor 16 -
FGF17 fibroblast growth factor 17 FGF-13
FGF18 fibroblast growth factor 18 FGF-18, ZFGF5
FGF19 fibroblast growth factor 19 -
FGF2 fibroblast growth factor 2 (basic) BFGF, FGFB, HBGF-2
FGF20 fibroblast growth factor 20 -
FGF21 fibroblast growth factor 21 -
FGF22 fibroblast growth factor 22 -
FGF23 fibroblast growth factor 23 ADHR, HPDR2, HYPF, PHPTC
FGF3 fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) HBGF-3, INT2
FGF4 fibroblast growth factor 4 HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF
FGF5 fibroblast growth factor 5 HBGF-5, Smag-82
FGF6 fibroblast growth factor 6 HBGF-6, HST2
FGF7 fibroblast growth factor 7 (keratinocyte growth factor) HBGF-7, KGF
FGF8 fibroblast growth factor 8 (androgen-induced) AIGF, HBGF-8, KAL6, MGC149376
FGF9 fibroblast growth factor 9 (glia-activating factor) GAF, HBFG-9, MGC119914, MGC119915
FGFR1 fibroblast growth factor receptor 1 BFGFR, CD331, CEK, FGFBR, FLG, FLJ99988, FLT2, HBGFR, KAL2, N-SAM, OGD
FGFR2 fibroblast growth factor receptor 2 BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25
FGFR3 fibroblast growth factor receptor 3 ACH, CD333, CEK2, HSFGFR3EX, JTK4
FGFR4 fibroblast growth factor receptor 4 CD334, JTK2, MGC20292, TKF
FGFRL1 fibroblast growth factor receptor-like 1 FGFR5, FHFR
FIGF c-fos induced growth factor (vascular endothelial growth factor D) VEGF-D, VEGFD
FIGNL2 fidgetin-like 2 -
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) FLT, VEGFR1
FLT3 fms-related tyrosine kinase 3 CD135, FLK2, STK1
FLT3LG fms-related tyrosine kinase 3 ligand FL
FLT4 fms-related tyrosine kinase 4 FLT41, LMPH1A, PCL, VEGFR3
FPR1 formyl peptide receptor 1 FMLP, FPR
FPR2 formyl peptide receptor 2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
FPR2 formyl peptide receptor 2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
FSHB follicle stimulating hormone, beta polypeptide -
FSHR follicle stimulating hormone receptor FSHRO, LGR1, MGC141667, MGC141668, ODG1
GAL galanin prepropeptide GALN, GLNN, GMAP, MGC40167
GALP galanin-like peptide -
GALR2 galanin receptor 2 GALNR2, MGC125983, MGC125984
GALR3 galanin receptor 3 -
GAST gastrin GAS
GCG glucagon GLP1, GLP2, GRPP
GCGR glucagon receptor GGR, MGC138246
GDF1 growth differentiation factor 1 -
GDF10 growth differentiation factor 10 BMP-3b, BMP3B
GDF11 growth differentiation factor 11 BMP-11, BMP11
GDF15 growth differentiation factor 15 GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
GDF2 growth differentiation factor 2 BMP-9, BMP9
GDF3 growth differentiation factor 3 -
GDF5 growth differentiation factor 5 BMP14, CDMP1, LAP4, OS5, SYNS2
GDF6 growth differentiation factor 6 BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1
GDF7 growth differentiation factor 7 BMP12
GDF9 growth differentiation factor 9 -
GDNF glial cell derived neurotrophic factor ATF1, ATF2, HFB1-GDNF
GH1 growth hormone 1 GH, GH-N, GHN, hGH-N
GH2 growth hormone 2 GH-V, GHL, GHV, hGH-V
GHR growth hormone receptor GHBP
GHRH growth hormone releasing hormone GHRF, GRF, MGC119781
GHRHR growth hormone releasing hormone receptor GHRFR, GHRHRpsv, GRFR
GHRL ghrelin/obestatin prepropeptide MTLRP, obestatin
GHSR growth hormone secretagogue receptor -
GIP gastric inhibitory polypeptide -
GIPR gastric inhibitory polypeptide receptor MGC126722
GKN1 gastrokine 1 AMP18, BRICD1, CA11, FOV, MGC70354, foveolin
GLP1R glucagon-like peptide 1 receptor MGC138331
GLP2R glucagon-like peptide 2 receptor -
GMFB glia maturation factor, beta GMF
GMFG glia maturation factor, gamma GMF-GAMMA, MGC126867
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) GNRH, GRH, LHRH, LNRH
GNRH2 gonadotropin-releasing hormone 2 GnRH-II, LH-RHII
GNRHR gonadotropin-releasing hormone receptor GNRHR1, GRHR, LHRHR, LRHR
GPER G protein-coupled estrogen receptor 1 CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678
GPHA2 glycoprotein hormone alpha 2 A2, GPA2, MGC126572, ZSIG51
GPHB5 glycoprotein hormone beta 5 B5, GPB5, ZLUT1
GPI glucose phosphate isomerase AMF, GNPI, NLK, PGI, PHI, SA-36
GPR17 G protein-coupled receptor 17 DKFZp686M18273
GPR32 G protein-coupled receptor 32 -
GPR33 G protein-coupled receptor 33 (gene/pseudogene) -
GPR44 G protein-coupled receptor 44 CD294, CRTH2, DP2
GPR77 G protein-coupled receptor 77 C5L2, GPF77
GREM1 gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, MGC126660, PIG2
GREM2 gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) CKTSF1B2, DAND3, PRDC
GRN granulin GEP, GP88, PCDGF, PEPI, PGRN
GRP gastrin-releasing peptide BN, GRP-10, preproGRP, proGRP
GUCA2A guanylate cyclase activator 2A (guanylin) GUANYLIN, GUCA2, STARA
HAMP hepcidin antimicrobial peptide HEPC, HEPCIDIN, HFE2B, LEAP-1, LEAP1, PLTR
HBEGF heparin-binding EGF-like growth factor DTR, DTS, DTSF, HEGFL
HDGF hepatoma-derived growth factor (high-mobility group protein 1-like) DKFZp686J1764, FLJ96580, HMG1L2
HDGFRP3 hepatoma-derived growth factor, related protein 3 CGI-142, HDGF2
HGF hepatocyte growth factor (hepapoietin A; scatter factor) F-TCF, HGFB, HPTA, SF
HNF4A hepatocyte nuclear factor 4, alpha FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
HNF4G hepatocyte nuclear factor 4, gamma NR2A2, NR2A3
HTN3 histatin 3 HIS2, HTN2, HTN5
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B 5-HT3B
HTR3C 5-hydroxytryptamine (serotonin) receptor 3, family member C -
HTR3D 5-hydroxytryptamine (serotonin) receptor 3 family member D MGC119636, MGC119637
HTR3E 5-hydroxytryptamine (serotonin) receptor 3, family member E 5-HT3c1, MGC120035, MGC120036, MGC120037
IAPP islet amyloid polypeptide AMYLIN, DAP, IAP
IFNA1 interferon, alpha 1 IFL, IFN, IFN-ALPHA, IFNA13, [email protected], MGC138207, MGC138505, MGC138507
IFNA10 interferon, alpha 10 MGC119878, MGC119879
IFNA13 interferon, alpha 13 -
IFNA14 interferon, alpha 14 LEIF2H, MGC125756, MGC125757
IFNA16 interferon, alpha 16 -
IFNA17 interferon, alpha 17 IFNA, INFA, LEIF2C1
IFNA2 interferon, alpha 2 IFNA, INFA2, MGC125764, MGC125765
IFNA21 interferon, alpha 21 MGC126687, MGC126689
IFNA4 interferon, alpha 4 INFA4, MGC142200
IFNA5 interferon, alpha 5 INFA5
IFNA6 interferon, alpha 6 -
IFNA7 interferon, alpha 7 IFNA-J
IFNA8 interferon, alpha 8 -
IFNAR1 interferon (alpha, beta and omega) receptor 1 AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC
IFNAR2 interferon (alpha, beta and omega) receptor 2 IFN-R, IFN-alpha-REC, IFNABR, IFNARB
IFNB1 interferon, beta 1, fibroblast IFB, IFF, IFNB, MGC96956
IFNE interferon, epsilon IFN-E, IFNE1, IFNT1, MGC119018, MGC119020, PRO655
IFNG interferon, gamma IFG, IFI
IFNGR1 interferon gamma receptor 1 CD119, FLJ45734, IFNGR
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) AF-1, IFGR2, IFNGT1
IFNK interferon, kappa RP11-27J8.1
IFNW1 interferon, omega 1 -
IGF1 insulin-like growth factor 1 (somatomedin C) IGF1A, IGFI
IGF1R insulin-like growth factor 1 receptor CD221, IGFIR, IGFR, JTK13, MGC142170, MGC142172, MGC18216
IGF2 insulin-like growth factor 2 (somatomedin A) C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974
IGF2R insulin-like growth factor 2 receptor CD222, CIMPR, M6P-R, MPR1, MPRI
IL10 interleukin 10 CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
IL10RA interleukin 10 receptor, alpha CDW210A, HIL-10R, IL-10R1, IL10R
IL10RB interleukin 10 receptor, beta CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
IL11 interleukin 11 AGIF, IL-11
IL11RA interleukin 11 receptor, alpha MGC2146
IL11RB interleukin 11 receptor, beta -
IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) CLMF, IL-12A, NFSK, NKSF1, P35
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) CLMF, CLMF2, IL-12B, NKSF, NKSF2
IL12RB1 interleukin 12 receptor, beta 1 CD212, IL-12R-BETA1, IL12RB, MGC34454
IL12RB2 interleukin 12 receptor, beta 2 -
IL13 interleukin 13 ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
IL13RA1 interleukin 13 receptor, alpha 1 CD213A1, IL-13Ra, NR4
IL13RA2 interleukin 13 receptor, alpha 2 CD213A2, CT19, IL-13R, IL13BP
IL15 interleukin 15 IL-15, MGC9721
IL15RA interleukin 15 receptor, alpha MGC104179
IL15RB interleukin 15 receptor, beta -
IL16 interleukin 16 (lymphocyte chemoattractant factor) FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16
IL17A interleukin 17A CTLA8, IL-17, IL-17A, IL17
IL17B interleukin 17B IL-17B, IL-20, MGC138900, MGC138901, ZCYTO7
IL17C interleukin 17C CX2, IL-17C, IL-21, MGC126884, MGC138401
IL17D interleukin 17D FLJ30846, IL-17D, IL-22, IL-27, IL27
IL17F interleukin 17F IL-17F, ML-1, ML1
IL17RA interleukin 17 receptor A CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
IL17RB interleukin 17 receptor B CRL4, EVI27, IL17BR, IL17RH1, MGC5245
IL17RC interleukin 17 receptor C FLJ95963, FLJ96005, IL17-RL, IL17RL, MGC10763
IL17RD interleukin 17 receptor D DKFZp434N1928, FLJ35755, IL-17RD, IL17RLM, MGC133309, SEF
IL17RE interleukin 17 receptor E FLJ23658, MGC71884
IL18 interleukin 18 (interferon-gamma-inducing factor) IGIF, IL-18, IL-1g, IL1F4, MGC12320
IL18R1 interleukin 18 receptor 1 CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP
IL18RAP interleukin 18 receptor accessory protein ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590
IL19 interleukin 19 IL-10C, MDA1, NG.1, ZMDA1
IL1A interleukin 1, alpha IL-1A, IL1, IL1-ALPHA, IL1F1
IL1B interleukin 1, beta IL-1, IL1-BETA, IL1F2
IL1F10 interleukin 1 family, member 10 (theta) FIL1-theta, FKSG75, IL-1HY2, IL1-theta, MGC119831, MGC119832, MGC119833
IL1F5 interleukin 1 family, member 5 (delta) FIL1, FIL1(DELTA), FIL1D, IL1HY1, IL1L1, IL1RP3, MGC29840
IL1F6 interleukin 1 family, member 6 (epsilon) FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), MGC129552, MGC129553
IL1F7 interleukin 1 family, member 7 (zeta) FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1
IL1F8 interleukin 1 family, member 8 (eta) FIL1, FIL1-(ETA), FIL1H, IL-1F8, IL-1H2, IL1-ETA, IL1H2, MGC126880, MGC126882
IL1F9 interleukin 1 family, member 9 IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1H1, IL1RP2
IL1R1 interleukin 1 receptor, type I CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
IL1R2 interleukin 1 receptor, type II CD121b, IL1RB, MGC47725
IL1RAP interleukin 1 receptor accessory protein C3orf13, FLJ37788, IL-1RAcP, IL1R3
IL1RL1 interleukin 1 receptor-like 1 DER4, FIT-1, MGC32623, ST2, ST2L, ST2V, T1
IL1RL2 interleukin 1 receptor-like 2 IL1R-rp2, IL1RRP2
IL1RN interleukin 1 receptor antagonist ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430
IL2 interleukin 2 IL-2, TCGF, lymphokine
IL20 interleukin 20 IL-20, IL10D, MGC96907, ZCYTO10
IL20RA interleukin 20 receptor, alpha FLJ40993, IL-20R1, ZCYTOR7
IL20RB interleukin 20 receptor beta DIRS1, FNDC6, IL-20R2, MGC34923
IL21 interleukin 21 IL-21, Za11
IL21R interleukin 21 receptor MGC10967, NILR
IL22 interleukin 22 IL-21, IL-22, IL-D110, IL-TIF, IL21, ILTIF, MGC79382, MGC79384, TIFIL-23, TIFa, zcyto18
IL22RA1 interleukin 22 receptor, alpha 1 CRF2-9, IL22R, IL22R1
IL22RA2 interleukin 22 receptor, alpha 2 CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510
IL23A interleukin 23, alpha subunit p19 IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF
IL23R interleukin 23 receptor -
IL24 interleukin 24 C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7
IL25 interleukin 25 IL-17E, IL-25, IL17E
IL26 interleukin 26 AK155, IL-26
IL27 interleukin 27 IL-27, IL-27A, IL27p28, IL30, MGC71873, p28
IL27RA interleukin 27 receptor, alpha CRL1, IL27R, TCCR, WSX1, zcytor1
IL28A interleukin 28A (interferon, lambda 2) IFNL2, IL-28A
IL28B interleukin 28B (interferon, lambda 3) IFNL3, IL-28B, IL28C
IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor) CRF2/12, IFNLR, IFNLR1, IL-28R1, LICR2
IL29 interleukin 29 (interferon, lambda 1) IFNL1, IL-29
IL2RA interleukin 2 receptor, alpha CD25, IDDM10, IL2R, TCGFR
IL2RB interleukin 2 receptor, beta CD122, P70-75
IL2RG interleukin 2 receptor, gamma (severe combined immunodeficiency) CD132, IMD4, SCIDX, SCIDX1
IL3 interleukin 3 (colony-stimulating factor, multiple) IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF
IL31 interleukin 31 IL-31
IL31RA interleukin 31 receptor A CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384
IL32 interleukin 32 IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd
IL33 interleukin 33 C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2
IL34 interleukin 34 C16orf77, IL-34, MGC34647
IL3RA interleukin 3 receptor, alpha (low affinity) CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra
IL4 interleukin 4 BCGF-1, BCGF1, BSF1, IL-4, MGC79402
IL4R interleukin 4 receptor CD124, IL4RA
IL5 interleukin 5 (colony-stimulating factor, eosinophil) EDF, IL-5, TRF
IL5RA interleukin 5 receptor, alpha CD125, CDw125, HSIL5R3, IL5R, MGC26560
IL6 interleukin 6 (interferon, beta 2) BSF2, HGF, HSF, IFNB2, IL-6
IL6R interleukin 6 receptor CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) CD130, CDw130, GP130, GP130-RAPS, IL6R-beta
IL7 interleukin 7 IL-7
IL7R interleukin 7 receptor CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
IL8 interleukin 8 CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
IL8RA interleukin 8 receptor, alpha C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA
IL8RB interleukin 8 receptor, beta CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA
IL9 interleukin 9 HP40, IL-9, P40
IL9R interleukin 9 receptor CD129
INHA inhibin, alpha -
INHBA inhibin, beta A EDF, FRP
INHBB inhibin, beta B MGC157939
INHBC inhibin, beta C IHBC
INHBE inhibin, beta E MGC4638
INS insulin ILPR, IRDN
INS-IGF2 INS-IGF2 readthrough transcript -
INSL3 insulin-like 3 (Leydig cell) MGC119818, MGC119819, RLF, RLNL
INSL4 insulin-like 4 (placenta) EPIL, PLACENTIN
INSL5 insulin-like 5 MGC126695, MGC126697, PRO182, UNQ156
INSL6 insulin-like 6 RIF1
INSR insulin receptor CD220, HHF5
JAG1 jagged 1 (Alagille syndrome) AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644
JAG2 jagged 2 HJ2, SER2
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) CD309, FLK1, VEGFR, VEGFR2
KGFLP1 keratinocyte growth factor-like protein 1 MGC125746, MGC125747, MGC126891
KGFLP2 keratinocyte growth factor-like protein 2 -
KITLG KIT ligand DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, SHEP7
KL klotho -
LACRT lacritin MGC71934
LECT2 leukocyte cell-derived chemotaxin 2 MGC126628, chm-II, chm2
LEFTY1 left-right determination factor 1 LEFTB, LEFTYB
LEFTY2 left-right determination factor 2 EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
LEP leptin FLJ94114, OB, OBS
LEPR leptin receptor CD295, OBR
LGR4 leucine-rich repeat-containing G protein-coupled receptor 4 GPR48
LGR5 leucine-rich repeat-containing G protein-coupled receptor 5 FEX, GPR49, GPR67, GRP49, HG38, MGC117008
LGR6 leucine-rich repeat-containing G protein-coupled receptor 6 FLJ14471, GPCR, VTS20631
LHB luteinizing hormone beta polypeptide CGB4, LSH-B, hLHB
LHCGR luteinizing hormone/choriogonadotropin receptor FLJ41504, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R
LIF leukemia inhibitory factor (cholinergic differentiation factor) CDF, DIA, HILDA
LIFR leukemia inhibitory factor receptor alpha CD118, FLJ98106, FLJ99923, LIF-R, SJS2, STWS, SWS
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 FLJ31641, RIFLE, TAL
LTA lymphotoxin alpha (TNF superfamily, member 1) LT, TNFB, TNFSF1
LTB lymphotoxin beta (TNF superfamily, member 3) TNFC, TNFSF3, p33
LTB4R leukotriene B4 receptor BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
LTB4R2 leukotriene B4 receptor 2 BLT2, BLTR2, JULF2, KPG_004, NOP9
LTBP1 latent transforming growth factor beta binding protein 1 MGC163161
LTBP2 latent transforming growth factor beta binding protein 2 C14orf141, LTBP3, MSTP031
LTBP3 latent transforming growth factor beta binding protein 3 DKFZp586M2123, FLJ33431, FLJ39893, FLJ42533, FLJ44138, FLJ45576, LTBP-3, LTBP2, pp6425
LTBP4 latent transforming growth factor beta binding protein 4 FLJ46318, FLJ90018, LTBP-4, LTBP-4L
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) MGC14337, MSH-R, SHEP2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) ACTHR, MGC125798
MC3R melanocortin 3 receptor BMIQ9, MC3, MC3-R, OB20, OQTL
MC4R melanocortin 4 receptor MGC126851, MGC138197
MCHR1 melanin-concentrating hormone receptor 1 GPR24, MCH1R, MGC32129, SLC1
MCHR2 melanin-concentrating hormone receptor 2 GPR145, MCH2, MCH2R, SLT
MDK midkine (neurite growth-promoting factor 2) FLJ27379, MK, NEGF2
MET met proto-oncogene (hepatocyte growth factor receptor) AUTS9, HGFR, RCCP2, c-Met
MIA melanoma inhibitory activity CD-RAP
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) GIF, GLIF, MMIF
MLN motilin MGC138519
MLNR motilin receptor GPR38, MTLR1
MPL myeloproliferative leukemia virus oncogene C-MPL, CD110, MPLV, TPOR
MSTN myostatin GDF8
MTNR1A melatonin receptor 1A MEL-1A-R, MT1
MTNR1B melatonin receptor 1B MEL-1B-R, MT2
NAMPT nicotinamide phosphoribosyltransferase 1110035O14Rik, DKFZp666B131, MGC117256, PBEF, PBEF1, VF, VISFATIN
NDP Norrie disease (pseudoglioma) EVR2, FEVR, ND
NENF neuron derived neurotrophic factor CIR2, NEUDESIN, SCIRP10, SPUF
NGF nerve growth factor (beta polypeptide) Beta-NGF, HSAN5, MGC161426, MGC161428, NGFB
NGFR nerve growth factor receptor (TNFR superfamily, member 16) CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
NMB neuromedin B MGC17211, MGC2277, MGC3936
NMBR neuromedin B receptor -
NODAL nodal homolog (mouse) MGC138230
NOV nephroblastoma overexpressed gene CCN3, IGFBP9
NPFF neuropeptide FF-amide peptide precursor FMRFAL
NPPA natriuretic peptide precursor A ANF, ANP, ATFB6, CDD-ANF, PND
NPPB natriuretic peptide precursor B BNP
NPPC natriuretic peptide precursor C CNP
NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) ANPRA, ANPa, GUC2A, GUCY2A, NPRA
NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) ANPRC, GUCY2B, NPRC
NPY neuropeptide Y PYY4
NR0B1 nuclear receptor subfamily 0, group B, member 1 AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1
NR0B2 nuclear receptor subfamily 0, group B, member 2 FLJ17090, SHP, SHP1
NR1D1 nuclear receptor subfamily 1, group D, member 1 EAR1, THRA1, THRAL, ear-1, hRev
NR1D2 nuclear receptor subfamily 1, group D, member 2 BD73, EAR-1R, RVR
NR1H2 nuclear receptor subfamily 1, group H, member 2 LXR-b, LXRB, NER, NER-I, RIP15, UNR
NR1H3 nuclear receptor subfamily 1, group H, member 3 LXR-a, LXRA, RLD-1
NR1H4 nuclear receptor subfamily 1, group H, member 4 BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
NR1I2 nuclear receptor subfamily 1, group I, member 2 BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
NR1I3 nuclear receptor subfamily 1, group I, member 3 CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
NR2C1 nuclear receptor subfamily 2, group C, member 1 TR2
NR2C2 nuclear receptor subfamily 2, group C, member 2 TAK1, TR2R1, TR4, hTAK1
NR2E1 nuclear receptor subfamily 2, group E, member 1 TLL, TLX, XTLL
NR2E3 nuclear receptor subfamily 2, group E, member 3 ESCS, MGC49976, PNR, RNR, RP37, rd7
NR2F1 nuclear receptor subfamily 2, group F, member 1 COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1
NR2F2 nuclear receptor subfamily 2, group F, member 2 ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2
NR2F6 nuclear receptor subfamily 2, group F, member 6 EAR-2, EAR2, ERBAL2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) GCCR, GCR, GR, GRL
NR3C2 nuclear receptor subfamily 3, group C, member 2 MCR, MGC133092, MLR, MR
NR4A1 nuclear receptor subfamily 4, group A, member 1 GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
NR4A2 nuclear receptor subfamily 4, group A, member 2 HZF-3, NOT, NURR1, RNR1, TINUR
NR4A3 nuclear receptor subfamily 4, group A, member 3 CHN, CSMF, MINOR, NOR1, TEC
NR5A1 nuclear receptor subfamily 5, group A, member 1 AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1
NR5A2 nuclear receptor subfamily 5, group A, member 2 B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, hB1F, hB1F-2
NR6A1 nuclear receptor subfamily 6, group A, member 1 GCNF, GCNF1, NR61, RTR
NRG1 neuregulin 1 ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, NDF, SMDF
NRG2 neuregulin 2 Don-1, HRG2, NTAK
NRG3 neuregulin 3 HRG3, pro-NRG3
NRG4 neuregulin 4 DKFZp779N0541, DKFZp779N1944, HRG4
NRP1 neuropilin 1 BDCA4, CD304, DKFZp686A03134, DKFZp781F1414, NP1, NRP, VEGF165R
NRP2 neuropilin 2 MGC126574, NP2, NPN2, PRO2714, VEGF165R2
NRTN neurturin NTN
NTF3 neurotrophin 3 HDNF, MGC129711, NGF-2, NGF2, NT3
NTF4 neurotrophin 4 NT-4/5, NT4, NT5, NTF5
NTS neurotensin NMN-125, NN, NT, NT/N, NTS1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 ASFGF2, FGF-2, FGF-AS, FGF2AS, bFGF, gfg, gfg-1
OGFR opioid growth factor receptor -
OGN osteoglycin DKFZp586P2421, OG, OIF, SLRR3A
OPRD1 opioid receptor, delta 1 OPRD
OPRK1 opioid receptor, kappa 1 KOR, OPRK
OPRL1 opiate receptor-like 1 KOR-3, MGC34578, NOCIR, OOR, ORL1
OPRM1 opioid receptor, mu 1 KIAA0403, LMOR, MOR, MOR1, OPRM
OSGIN1 oxidative stress induced growth inhibitor 1 BDGI, OKL38
OSM oncostatin M MGC20461
OSMR oncostatin M receptor MGC150626, MGC150627, MGC75127, OSMRB
OSTN osteocrin MUSCLIN
OXT oxytocin, prepropeptide MGC126890, MGC126892, OT, OT-NPI
OXTR oxytocin receptor OT-R
P11 26 serine protease MGC133268, PP11, PRSS26
PDGFA platelet-derived growth factor alpha polypeptide PDGF-A, PDGF1
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) FLJ12858, PDGF2, SIS, SSV, c-sis
PDGFC platelet derived growth factor C FALLOTEIN, SCDGF
PDGFD platelet derived growth factor D IEGF, MGC26867, MSTP036, SCDGF-B, SCDGFB
PDGFRA platelet-derived growth factor receptor, alpha polypeptide CD140A, MGC74795, PDGFR2, Rhe-PDGFRA
PDGFRB platelet-derived growth factor receptor, beta polypeptide CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1
PDGFRL platelet-derived growth factor receptor-like PDGRL, PRLTS
PDYN prodynorphin MGC26418, PENKB
PENK proenkephalin -
PF4 platelet factor 4 CXCL4, MGC138298, SCYB4
PF4V1 platelet factor 4 variant 1 CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1
PGF placental growth factor D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
PGR progesterone receptor NR3C3, PR
PGRMC2 progesterone receptor membrane component 2 DG6, PMBP
PLAU plasminogen activator, urokinase ATF, UPA, URK, u-PA
PLAUR plasminogen activator, urokinase receptor CD87, UPAR, URKR
PLXNA1 plexin A1 NOV, NOVP, PLEXIN-A1, PLXN1
PLXNA2 plexin A2 FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
PLXNA3 plexin A3 6.3, HSSEXGENE, PLEXIN-A3, PLXN3, PLXN4, SEX, XAP-6
PLXNA4 plexin A4 DKFZp434G0625, DKFZp566O0546, FAYV2820, FLJ35026, FLJ38287, KIAA1550, PLEXA4, PLXNA4A, PLXNA4B, PRO34003
PLXNB1 plexin B1 KIAA0407, MGC149167, PLEXIN-B1, PLXN5, SEP
PLXNB2 plexin B2 KIAA0315, MM1, Nbla00445, PLEXB2, dJ402G11.3
PLXNB3 plexin B3 FLJ76953, PLEXB3, PLEXR, PLXN6
PLXNC1 plexin C1 CD232, PLXN-C1, VESPR
PLXND1 plexin D1 KIAA0620, MGC75353, PLEXD1
PMCH pro-melanin-concentrating hormone MCH
PNOC prepronociceptin PPNOC
POMC proopiomelanocortin ACTH, CLIP, LPH, MSH, NPP, POC
PPARA peroxisome proliferator-activated receptor alpha MGC2237, MGC2452, NR1C1, PPAR, hPPAR
PPARD peroxisome proliferator-activated receptor delta FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB
PPARG peroxisome proliferator-activated receptor gamma CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
PPBPL1 pro-platelet basic protein-like 1 TGB2
PPBPL2 pro-platelet basic protein-like 2 SPBPBP
PPY pancreatic polypeptide PNP
PRL prolactin -
PRLH prolactin releasing hormone PRH, PRRP
PRLHR prolactin releasing hormone receptor GPR10, GR3, MGC126539, MGC126541, PrRPR
PRLR prolactin receptor hPRLrI
PROK1 prokineticin 1 EGVEGF, PK1, PRK1
PROK2 prokineticin 2 BV8, KAL4, MIT1, PK2
PSPN persephin PSP
PTAFR platelet-activating factor receptor PAFR
PTGDR prostaglandin D2 receptor (DP) AS1, ASRT1, DP, DP1, MGC49004
PTGDS prostaglandin D2 synthase 21kDa (brain) LPGDS, PDS, PGD2, PGDS, PGDS2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa EP1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa EP2
PTGER3 prostaglandin E receptor 3 (subtype EP3) EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302
PTGER4 prostaglandin E receptor 4 (subtype EP4) EP4, EP4R, MGC126583
PTGFR prostaglandin F receptor (FP) FP, MGC120498, MGC46203
PTH parathyroid hormone PTH1
PTH1R parathyroid hormone 1 receptor MGC138426, MGC138452, PFE, PTHR, PTHR1
PTH2 parathyroid hormone 2 TIP39
PTH2R parathyroid hormone 2 receptor PTHR2
PTHLH parathyroid hormone-like hormone HHM, MGC14611, PLP, PTHR, PTHRP
PTN pleiotrophin HARP, HBGF8, HBNF, NEGF1
PYY peptide YY PYY1
QRFP pyroglutamylated RFamide peptide 26RFa, MGC119794, P518
RABEP1 rabaptin, RAB GTPase binding effector protein 1 RAB5EP, RABPT5
RABEP2 rabaptin, RAB GTPase binding effector protein 2 FLJ23282, FRA
RARA retinoic acid receptor, alpha NR1B1, RAR
RARB retinoic acid receptor, beta HAP, NR1B2, RRB2
RARG retinoic acid receptor, gamma NR1B3, RARC
REG1A regenerating islet-derived 1 alpha ICRF, MGC12447, P19, PSP, PSPS, PSPS1, PTP, REG
RETN resistin ADSF, FIZZ3, MGC126603, MGC126609, RETN1, RSTN, XCP1
RETNLB resistin like beta FIZZ1, FIZZ2, HXCP2, RELM-beta, RELMb, RELMbeta, XCP2
RLN1 relaxin 1 H1, RLXH1, bA12D24.3.1, bA12D24.3.2
RLN2 relaxin 2 H2, RLXH2, bA12D24.1.1, bA12D24.1.2
RLN3 relaxin 3 H3, RXN3, ZINS4, insl7
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) EDN, RNS2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) DUTT1, FLJ21882, MGC131599, MGC133277, SAX3
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) KIAA1568, SAX3
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) FLJ21044, HGPPS, HGPS, RBIG1, RIG1
RORA RAR-related orphan receptor A DKFZp686M2414, MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA
RORB RAR-related orphan receptor B NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
RORC RAR-related orphan receptor C MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR
RXFP1 relaxin/insulin-like family peptide receptor 1 LGR7, LGR7.1, LGR7.10, LGR7.2, MGC138347, MGC142177, RXFPR1
RXFP2 relaxin/insulin-like family peptide receptor 2 GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2
RXFP3 relaxin/insulin-like family peptide receptor 3 GPCR135, MGC141998, MGC142000, RLN3R1, RXFPR3, SALPR
RXRA retinoid X receptor, alpha FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, NR2B1
RXRB retinoid X receptor, beta DAUDI6, H-2RIIBP, MGC1831, NR2B2, RCoR-1
RXRG retinoid X receptor, gamma NR2B3, RXRC
S100A6 S100 calcium binding protein A6 2A9, 5B10, CABP, CACY, PRA
S1PR1 sphingosine-1-phosphate receptor 1 CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
S1PR2 sphingosine-1-phosphate receptor 2 AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
SAA1 serum amyloid A1 MGC111216, PIG4, SAA, TP53I4
SAA2 serum amyloid A2 -
SBDS Shwachman-Bodian-Diamond syndrome CGI-97, FLJ10917, SDS, SWDS
SCG2 secretogranin II (chromogranin C) CHGC, SN, SgII
SCGB3A1 secretoglobin, family 3A, member 1 HIN-1, HIN1, LU105, MGC87867, PnSP-2, UGRP2
SCT secretin -
SCTR secretin receptor SR
SCYE1 small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) AIMP1, EMAP2, EMAPII, p43
SDC1 syndecan 1 CD138, SDC, SYND1, syndecan
SDC2 syndecan 2 HSPG, HSPG1, SYND2
SDC3 syndecan 3 N-syndecan, SDCN, SYND3
SDC4 syndecan 4 MGC22217, SYND4
SECTM1 secreted and transmembrane 1 K12
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B FLJ34863, LUCA-1, SEMA5, SEMAA, SemA, semaV
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C SEMAE, SemE
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D MGC39708, Sema-Z2, coll-2
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E KIAA0331, M-SEMAH, M-SemaK, SEMAH, coll-5
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F SEMA-IV, SEMA4, SEMAK
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G FLJ00014, MGC119473, sem2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A CORD10, FLJ12287, RP35, SEMAB, SEMB
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B KIAA1745, MGC131831, SEMAC, SemC
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C FLJ20369, KIAA1739, M-SEMA-F, MGC126382, MGC126383, SEMACL1, SEMAF, SEMAI
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D C9orf164, CD100, FLJ33485, FLJ34282, FLJ39737, FLJ46484, M-sema-G, MGC169138, MGC169141, SEMAJ, coll-4
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F M-SEMA, PRO2353, SEMAM, SEMAW, m-Sema-M
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G FLJ20590, KIAA1619, MGC102867
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A FLJ12815, SEMAF, semF
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B FLJ10372, KIAA1445, SEMAG, SemG
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ, VIA
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C SEMAY, m-SemaY, m-SemaY2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D FLJ11598, KIAA1479
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, MGC126692, MGC126696, SEMAK1, SEMAL
SLIT1 slit homolog 1 (Drosophila) MEGF4, MGC164811, SLIL1, SLIT3, Slit-1
SLIT2 slit homolog 2 (Drosophila) FLJ14420, SLIL3, Slit-2
SLURP1 secreted LY6/PLAUR domain containing 1 ANUP, ARS, ArsB, LY6LS, MDM
SORT1 sortilin 1 Gp95, NT3
SPP1 secreted phosphoprotein 1 BNSP, BSPI, ETA-1, MGC110940, OPN
SST somatostatin SMST
SSTR1 somatostatin receptor 1 SRIF-2
SSTR2 somatostatin receptor 2 -
SSTR5 somatostatin receptor 5 -
ST2 suppression of tumorigenicity 2 -
STC1 stanniocalcin 1 STC
STC2 stanniocalcin 2 STC-2, STCRP
TAC1 tachykinin, precursor 1 Hs.2563, NK2, NKNA, NPK, TAC2
TACR1 tachykinin receptor 1 NK1R, NKIR, SPR, TAC1R
TDGF1 teratocarcinoma-derived growth factor 1 CR, CRGF, CRIPTO, Cripto-1
TDGF3 teratocarcinoma-derived growth factor 3, pseudogene CR-3, CRIPTO, CRIPTO-3, TDGF1, TDGF2
TEK TEK tyrosine kinase, endothelial CD202B, TIE-2, TIE2, VMCM, VMCM1
TG thyroglobulin AITD3, TGN
TGFA transforming growth factor, alpha TFGA
TGFB1 transforming growth factor, beta 1 CED, DPD1, TGFB, TGFbeta
TGFB2 transforming growth factor, beta 2 MGC116892, TGF-beta2
TGFB3 transforming growth factor, beta 3 ARVD, FLJ16571, TGF-beta3
TGFBR1 transforming growth factor, beta receptor 1 AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
TGFBR3 transforming growth factor, beta receptor III BGCAN, betaglycan
THPO thrombopoietin MGC163194, MGDF, MKCSF, ML, MPLLG, TPO
THRA thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1
THRB thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, PRTH, THR1, THRB1, THRB2
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 JTK14, TIE
TNC tenascin C HXB, MGC167029, TN
TNF tumor necrosis factor (TNF superfamily, member 2) DIF, TNF-alpha, TNFA, TNFSF2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain CD264, DCR2, TRAILR4, TRUNDD
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b MGC29565, OCIF, OPG, TR1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A CD266, FN14, TWEAKR
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C BAFF-R, BAFFR, CD268, MGC138235
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) ATAR, HVEA, HVEM, LIGHTR, TR2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 BCM, BCMA, CD269
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 AITR, GITR, GITR-D
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 TAJ, TAJ-alpha, TRADE, TROY
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A CD120a, FPF, MGC19588, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 BM-018, DR6, MGC31965
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 ACT35, CD134, OX40, TXGP1L
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy DCR3, DJ583P15.1.1, M68, TR6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 CD30, D1S166E, Ki-1
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 4-1BB, CD137, CDw137, ILA, MGC2172
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 APO2L, Apo-2L, CD253, TL2, TRAIL
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 APO3L, DR3LG, MGC129581, MGC20669, TWEAK
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 CD258, HVEML, LIGHT, LTg, TR2
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 AITRL, GITRL, MGC138237, TL6, hGITRL
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 CD153, CD30L, CD30LG, MGC138144
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 4-1BB-L, CD137L
TOR2A torsin family 2, member A FLJ14771, MGC99558, TORP1
TRH thyrotropin-releasing hormone MGC125964, MGC125965
TRHR thyrotropin-releasing hormone receptor MGC141920
TSHB thyroid stimulating hormone, beta CHNG4, TSH-BETA
TSHR thyroid stimulating hormone receptor CHNG1, LGR3, MGC75129, hTSHR-I
TSLP thymic stromal lymphopoietin -
TUBB3 tubulin, beta 3 MC1R, TUBB4, beta-4
TXLNA taxilin alpha DKFZp451J0118, IL14, MGC118870, MGC118871, RP4-622L5.4, TXLN
TYMP thymidine phosphorylase ECGF1, MNGIE, PDECGF, TP, hPD-ECGF
UCN urocortin MGC129974, MGC129975, UI, UROC
UCN2 urocortin 2 SRP, UCN-II, UCNI, UR, URP
UCN3 urocortin 3 (stresscopin) MGC119002, SCP, SPC, UCNIII
UTS2 urotensin 2 PRO1068, U-II, UCN2, UII
UTS2D urotensin 2 domain containing MGC138371, U2B, URP
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor NR1I1
VEGFA vascular endothelial growth factor A MGC70609, MVCD1, VEGF, VEGF-A, VPF
VEGFB vascular endothelial growth factor B VEGFL, VRF
VEGFC vascular endothelial growth factor C Flt4-L, VRP
VGF VGF nerve growth factor inducible -
VIP vasoactive intestinal peptide MGC13587, PHM27
VIPR1 vasoactive intestinal peptide receptor 1 FLJ41949, HVR1, II, PACAP-R-2, RDC1, VAPC1, VIPR, VIRG, VPAC1, VPCAP1R
VIPR2 vasoactive intestinal peptide receptor 2 FLJ16511, VPAC2, VPCAP2R
XCL1 chemokine (C motif) ligand 1 ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1
XCL2 chemokine (C motif) ligand 2 SCM-1b, SCM1B, SCYC2
XCR1 chemokine (C motif) receptor 1 CCXCR1, GPR5

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Cytokines Icon Interferons

The interferon family of signaling proteins consists of Type I, Type II, and Type III interferons. They trigger the defensive responses of the immune system upon infection with virus and, like other cytokines, enable communication between cells of the immune system.

Symbol Name Synonyms
IFNA10 interferon, alpha 10 MGC119878, MGC119879
IFNA13 interferon, alpha 13 -
IFNA14 interferon, alpha 14 LEIF2H, MGC125756, MGC125757
IFNA16 interferon, alpha 16 -
IFNA17 interferon, alpha 17 IFNA, INFA, LEIF2C1
IFNA2 interferon, alpha 2 IFNA, INFA2, MGC125764, MGC125765
IFNA21 interferon, alpha 21 MGC126687, MGC126689
IFNA4 interferon, alpha 4 INFA4, MGC142200
IFNA5 interferon, alpha 5 INFA5
IFNA6 interferon, alpha 6 -
IFNA7 interferon, alpha 7 IFNA-J
IFNA8 interferon, alpha 8 -
IFNAR2 interferon (alpha, beta and omega) receptor 2 IFN-R, IFN-alpha-REC, IFNABR, IFNARB
IFNB1 interferon, beta 1, fibroblast IFB, IFF, IFNB, MGC96956
IFNE interferon, epsilon IFN-E, IFNE1, IFNT1, MGC119018, MGC119020, PRO655
IFNG interferon, gamma IFG, IFI
IFNGR1 interferon gamma receptor 1 CD119, FLJ45734, IFNGR
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) AF-1, IFGR2, IFNGT1
IFNK interferon, kappa RP11-27J8.1
IFNW1 interferon, omega 1 -

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Cytokines Icon Interleukins

Interleukins are cytokines that are secreted by immune cells and coordinate communication between immune cells over the course of an immune response. Over 60 interleukins have been described.

Symbol Name Synonyms
EBI3 Epstein-Barr Virus Induced 3 IL35B, IL27B, IL35 subunit
IL10RA interleukin 10 receptor, alpha CDW210A, HIL-10R, IL-10R1, IL10R
IL10RB interleukin 10 receptor, beta CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
IL11 interleukin 11 AGIF, IL-11
IL11RA interleukin 11 receptor, alpha MGC2146
IL11RB interleukin 11 receptor, beta -
IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) CLMF, IL-12A, NFSK, NKSF1, P35
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) CLMF, CLMF2, IL-12B, NKSF, NKSF2
IL12RB1 interleukin 12 receptor, beta 1 CD212, IL-12R-BETA1, IL12RB, MGC34454
IL12RB2 interleukin 12 receptor, beta 2 -
IL13 interleukin 13 ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
IL13RA1 interleukin 13 receptor, alpha 1 CD213A1, IL-13Ra, NR4
IL13RA2 interleukin 13 receptor, alpha 2 CD213A2, CT19, IL-13R, IL13BP
IL15 interleukin 15 IL-15, MGC9721
IL15RA interleukin 15 receptor, alpha MGC104179
IL15RB interleukin 15 receptor, beta -
IL16 interleukin 16 (lymphocyte chemoattractant factor) FLJ16806, FLJ42735, FLJ44234, HsT19289, IL-16, LCF, prIL-16
IL17A interleukin 17A CTLA8, IL-17, IL-17A, IL17
IL17B interleukin 17B IL-17B, IL-20, MGC138900, MGC138901, ZCYTO7
IL17C interleukin 17C CX2, IL-17C, IL-21, MGC126884, MGC138401
IL17D interleukin 17D FLJ30846, IL-17D, IL-22, IL-27, IL27
IL17F interleukin 17F IL-17F, ML-1, ML1
IL17RA interleukin 17 receptor A CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
IL17RB interleukin 17 receptor B CRL4, EVI27, IL17BR, IL17RH1, MGC5245
IL17RC interleukin 17 receptor C FLJ95963, FLJ96005, IL17-RL, IL17RL, MGC10763
IL17RD interleukin 17 receptor D DKFZp434N1928, FLJ35755, IL-17RD, IL17RLM, MGC133309, SEF
IL17RE interleukin 17 receptor E FLJ23658, MGC71884
IL18 interleukin 18 (interferon-gamma-inducing factor) IGIF, IL-18, IL-1g, IL1F4, MGC12320
IL18R1 interleukin 18 receptor 1 CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP
IL18RAP interleukin 18 receptor accessory protein ACPL, CD218b, CDw218b, IL18RB, MGC120589, MGC120590
IL19 interleukin 19 IL-10C, MDA1, NG.1, ZMDA1
IL1A interleukin 1, alpha IL-1A, IL1, IL1-ALPHA, IL1F1
IL1B interleukin 1, beta IL-1, IL1-BETA, IL1F2
IL1F10 interleukin 1 family, member 10 (theta) FIL1-theta, FKSG75, IL-1HY2, IL1-theta, MGC119831, MGC119832, MGC119833, IL38
IL1F5 interleukin 1 family, member 5 (delta) FIL1, FIL1(DELTA), FIL1D, IL1HY1, IL1L1, IL1RP3, MGC29840, IL36RN, IL36RA
IL1F6 interleukin 1 family, member 6 (epsilon) FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), MGC129552, MGC129553, IL36A
IL1F7 interleukin 1 family, member 7 (zeta) FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1H4, IL1RP1, IL37
IL1F8 interleukin 1 family, member 8 (eta) FIL1, FIL1-(ETA), FIL1H, IL-1F8, IL-1H2, IL1-ETA, IL1H2, MGC126880, MGC126882, IL36B
IL1F9 interleukin 1 family, member 9 IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1H1, IL1RP2, IL36G
IL1R1 interleukin 1 receptor, type I CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
IL1R2 interleukin 1 receptor, type II CD121b, IL1RB, MGC47725
IL1RAP interleukin 1 receptor accessory protein C3orf13, FLJ37788, IL-1RAcP, IL1R3
IL1RL1 interleukin 1 receptor-like 1 DER4, FIT-1, MGC32623, ST2, ST2L, ST2V, T1
IL1RL2 interleukin 1 receptor-like 2 IL1R-rp2, IL1RRP2, IL36R
IL1RN interleukin 1 receptor antagonist ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430
IL2 interleukin 2 IL-2, TCGF, lymphokine
IL20 interleukin 20 IL-20, IL10D, MGC96907, ZCYTO10
IL20RA interleukin 20 receptor, alpha FLJ40993, IL-20R1, ZCYTOR7
IL20RB interleukin 20 receptor beta DIRS1, FNDC6, IL-20R2, MGC34923
IL21 interleukin 21 IL-21, Za11
IL21R interleukin 21 receptor MGC10967, NILR
IL22 interleukin 22 IL-21, IL-22, IL-D110, IL-TIF, IL21, ILTIF, MGC79382, MGC79384, TIFIL-23, TIFa, zcyto18
IL22RA1 interleukin 22 receptor, alpha 1 CRF2-9, IL22R, IL22R1
IL22RA2 interleukin 22 receptor, alpha 2 CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510
IL23A interleukin 23, alpha subunit p19 IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF
IL23R interleukin 23 receptor -
IL24 interleukin 24 C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7
IL25 interleukin 25 IL-17E, IL-25, IL17E
IL26 interleukin 26 AK155, IL-26
IL27 interleukin 27 IL-27, IL-27A, IL27p28, IL30, MGC71873, p28
IL27RA interleukin 27 receptor, alpha CRL1, IL27R, TCCR, WSX1, zcytor1
IL28A interleukin 28A (interferon, lambda 2) IFNL2, IL-28A
IL28B interleukin 28B (interferon, lambda 3) IFNL3, IL-28B, IL28C
IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor) CRF2/12, IFNLR, IFNLR1, IL-28R1, LICR2
IL29 interleukin 29 (interferon, lambda 1) IFNL1, IL-29
IL2RA interleukin 2 receptor, alpha CD25, IDDM10, IL2R, TCGFR
IL2RB interleukin 2 receptor, beta CD122, P70-75
IL2RG interleukin 2 receptor, gamma (severe combined immunodeficiency) CD132, IMD4, SCIDX, SCIDX1
IL3 interleukin 3 (colony-stimulating factor, multiple) IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF
IL31 interleukin 31 IL-31
IL31RA interleukin 31 receptor A CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384
IL32 interleukin 32 IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd
IL33 interleukin 33 C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2
IL34 interleukin 34 C16orf77, IL-34, MGC34647
IL3RA interleukin 3 receptor, alpha (low affinity) CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra
IL4 interleukin 4 BCGF-1, BCGF1, BSF1, IL-4, MGC79402
IL4R interleukin 4 receptor CD124, IL4RA
IL5 interleukin 5 (colony-stimulating factor, eosinophil) EDF, IL-5, TRF
IL5RA interleukin 5 receptor, alpha CD125, CDw125, HSIL5R3, IL5R, MGC26560
IL6 interleukin 6 (interferon, beta 2) BSF2, HGF, HSF, IFNB2, IL-6
IL6R interleukin 6 receptor CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) CD130, CDw130, GP130, GP130-RAPS, IL6R-beta
IL7 interleukin 7 IL-7
IL7R interleukin 7 receptor CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
IL8 interleukin 8 CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
IL8RA interleukin 8 receptor, alpha C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, CXCR1, IL8R1, IL8RBA
IL8RB interleukin 8 receptor, beta CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA
IL9 interleukin 9 HP40, IL-9, P40
IL9R interleukin 9 receptor CD129
ST2 suppression of tumorigenicity 2 -
TXLNA taxilin alpha DKFZp451J0118, IL14, MGC118870, MGC118871, RP4-622L5.4, TXLN

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NK cell cytotoxicity icon NK Cell Signaling

Natural killer (NK) cells can kill cells that have been infected by a foreign pathogen. They detect infected cells via receptors such as KIR and NKG2D. Upon activation, NK cells secrete perforin and granzyme B, two enzymes that create pores within an infected cell membrane, triggering cell death.

Symbol Name Synonyms
ARAF v-raf murine sarcoma 3611 viral oncogene homolog A-RAF, ARAF1, PKS2, RAFA1
BID BH3 interacting domain death agonist FP497, MGC15319, MGC42355
BRAF v-raf murine sarcoma viral oncogene homolog B1 B-RAF1, BRAF1, FLJ95109, MGC126806, MGC138284, RAFB1
CASP3 caspase 3, apoptosis-related cysteine peptidase CPP32, CPP32B, SCA-1
CD244 CD244 molecule, natural killer cell receptor 2B4 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
CD247 CD247 molecule CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
CD48 CD48 molecule BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48
CHP calcium binding protein P22 SLC9A1BP
CHP2 calcineurin B homologous protein 2 -
CSF2 colony stimulating factor 2 (granulocyte-macrophage) GMCSF, MGC131935, MGC138897
FAS Fas (TNF receptor superfamily, member 6) ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
FASLG Fas ligand (TNF superfamily, member 6) APT1LG1, CD178, CD95L, FASL, TNFSF6
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide FCRG
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) CD16, CD16b, FCG3, FCGR3
FYN FYN oncogene related to SRC, FGR, YES MGC45350, SLK, SYN
GRB2 growth factor receptor-bound protein 2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
HCST hematopoietic cell signal transducer DAP10, DKFZP586C1522, KAP10, PIK3AP
HLA-A major histocompatibility complex, class I, A FLJ26655, HLAA
HLA-B major histocompatibility complex, class I, B AS, HLA-B-7301, HLA-B73, HLAB, HLAC, MGC111087, SPDA1
HLA-C major histocompatibility complex, class I, C D6S204, FLJ27082, HLA-Cw, HLA-Cw12, HLA-JY3, HLC-C, PSORS1
HLA-E major histocompatibility complex, class I, E DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
HLA-G major histocompatibility complex, class I, G MHC-G
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
ICAM1 intercellular adhesion molecule 1 BB2, CD54, P3.58
ICAM2 intercellular adhesion molecule 2 CD102
IFNA1 interferon, alpha 1 IFL, IFN, IFN-ALPHA, IFNA13, [email protected], MGC138207, MGC138505, MGC138507
IFNA10 interferon, alpha 10 MGC119878, MGC119879
IFNA13 interferon, alpha 13 -
IFNA14 interferon, alpha 14 LEIF2H, MGC125756, MGC125757
IFNA16 interferon, alpha 16 -
IFNA17 interferon, alpha 17 IFNA, INFA, LEIF2C1
IFNA2 interferon, alpha 2 IFNA, INFA2, MGC125764, MGC125765
IFNA21 interferon, alpha 21 MGC126687, MGC126689
IFNA4 interferon, alpha 4 INFA4, MGC142200
IFNA5 interferon, alpha 5 INFA5
IFNA6 interferon, alpha 6 -
IFNA7 interferon, alpha 7 IFNA-J
IFNA8 interferon, alpha 8 -
IFNAR1 interferon (alpha, beta and omega) receptor 1 AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC
IFNAR2 interferon (alpha, beta and omega) receptor 2 IFN-R, IFN-alpha-REC, IFNABR, IFNARB
IFNB1 interferon, beta 1, fibroblast IFB, IFF, IFNB, MGC96956
IFNG interferon, gamma IFG, IFI
IFNGR1 interferon gamma receptor 1 CD119, FLJ45734, IFNGR
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) AF-1, IFGR2, IFNGT1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) CD11A, LFA-1, LFA1A
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 CD158B1, CD158b, NKAT6, p58.2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 CD158B2, CD158b, GL183, KIR-023GB, KIR-K7b, KIR-K7c, KIRCL23, MGC129943, NKAT, NKAT2, NKAT2A, NKAT2B, p58
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 CD158D, G9P, KIR103, KIR103AS
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 CD158H, CD158a, p50.1
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 NKAT7
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 CD158I, KIR1D, KIR412, KKA3, MGC120019, MGC125315, MGC125317, NKAT8
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 CD158G, NKAT9
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 CD158E1, KIR, MGC119726, MGC119728, MGC126589, MGC126591, NKAT3, NKB1, NKB1B
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 CD158K, MGC125321, NKAT4, NKAT4B, p140
KLRC1 killer cell lectin-like receptor subfamily C, member 1 CD159A, MGC13374, MGC59791, NKG2, NKG2A
KLRC2 killer cell lectin-like receptor subfamily C, member 2 CD159c, MGC138244, NKG2-C, NKG2C
KLRC3 killer cell lectin-like receptor subfamily C, member 3 NKG2-E, NKG2E
KLRD1 killer cell lectin-like receptor subfamily D, member 1 CD94
KLRK1 killer cell lectin-like receptor subfamily K, member 1 CD314, D12S2489E, FLJ17759, FLJ75772, KLR, NKG2-D, NKG2D
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2
LAT linker for activation of T cells LAT1, pp36
LCK lymphocyte-specific protein tyrosine kinase YT16, p56lck, pp58lck
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) SLP-76, SLP76
LOC652578 similar to Fc fragment of IgG, low affinity IIIa, receptor for (CD16) -
MAP2K1 mitogen-activated protein kinase kinase 1 MAPKK1, MEK1, MKK1, PRKMK1
MAP2K2 mitogen-activated protein kinase kinase 2 FLJ26075, MAPKK2, MEK2, MKK2, PRKMK2
MAPK1 mitogen-activated protein kinase 1 ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
MAPK3 mitogen-activated protein kinase 3 ERK1, HS44KDAP, HUMKER1A, MGC20180, P44ERK1, P44MAPK, PRKM3
MICA MHC class I polypeptide-related sequence A FLJ60820, MGC111087, PERB11.1
MICB MHC class I polypeptide-related sequence B PERB11.2
NCR1 natural cytotoxicity triggering receptor 1 CD335, FLJ99094, LY94, NK-p46, NKP46
NCR2 natural cytotoxicity triggering receptor 2 CD336, LY95, NK-p44, NKP44, dJ149M18.1
NCR3 natural cytotoxicity triggering receptor 3 1C7, CD337, LY117, MALS, NKp30
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 MGC138448, NF-ATC, NFAT2, NFATc
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 NFAT1, NFATP
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFAT4, NFATX
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 NF-ATc4, NFAT3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog ALPS4, N-ras, NRAS1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 MGC130000, MGC130001, PAKalpha
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide MGC142161, MGC142163, PI3K, p110-alpha
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA
PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide p110D
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide PI3CG, PI3K, PI3Kgamma, PIK3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GRB1, p85, p85-ALPHA
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) P85B, p85, p85-BETA
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) DKFZp686P05226, FLJ41892, p55, p55-GAMMA
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 F730038I15Rik, FOAP-2, P101-PI3K, p101
PLCG1 phospholipase C, gamma 1 PLC-II, PLC1, PLC148, PLCgamma1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -
PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B
PPP3CB protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform CALNA2, CALNB
PPP3CC protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform CALNA3
PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform CALNB1, CNB, CNB1
PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform PPP3RL
PRF1 perforin 1 (pore forming protein) FLH2, HPLH2, MGC65093, P1, PFN1, PFP
PRKCA protein kinase C, alpha AAG6, MGC129900, MGC129901, PKC-alpha, PKCA, PRKACA
PRKCB protein kinase C, beta MGC41878, PKC-beta, PKCB, PRKCB1, PRKCB2
PRKCG protein kinase C, gamma MGC57564, PKC-gamma, PKCC, PKCG, SCA14
PTK2B PTK2B protein tyrosine kinase 2 beta CADTK, CAKB, FADK2, FAK2, FRNK, PKB, PTK, PYK2, RAFTK
PTPN11 protein tyrosine phosphatase, non-receptor type 11 BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
PTPN6 protein tyrosine phosphatase, non-receptor type 6 HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) MGC111543, MIG5, TC-25, p21-Rac1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) EN-7, Gx, HSPC022
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 CRAF, NS5, Raf-1, c-Raf
SH2D1A SH2 domain protein 1A DSHP, EBVS, FLJ18687, FLJ92177, IMD5, LYP, MTCP1, SAP, XLP, XLPD
SH2D1B SH2 domain containing 1B EAT2
SH3BP2 SH3-domain binding protein 2 3BP2, CRBM, CRPM, FLJ42079, FLJ54978, RES4-23
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 FLJ26504, SHC, SHCA
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 SCK, SHCB, SLI
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 N-Shc, NSHC, RAI, SHCC
SHC4 SHC (Src homology 2 domain containing) family, member 4 MGC34023, RaLP, SHCD
SOS1 son of sevenless homolog 1 (Drosophila) GF1, GGF1, GINGF, HGF, NS4
SOS2 son of sevenless homolog 2 (Drosophila) FLJ25596
SYK spleen tyrosine kinase DKFZp313N1010, FLJ25043, FLJ37489
TNF tumor necrosis factor (TNF superfamily, member 2) DIF, TNF-alpha, TNFA, TNFSF2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain CD264, DCR2, TRAILR4, TRUNDD
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 APO2L, Apo-2L, CD253, TL2, TRAIL
TYROBP TYRO protein tyrosine kinase binding protein DAP12, KARAP, PLOSL
ULBP1 UL16 binding protein 1 RAET1I
ULBP2 UL16 binding protein 2 N2DL2, RAET1H
ULBP3 UL16 binding protein 3 RAET1N
VAV1 vav 1 guanine nucleotide exchange factor VAV
VAV2 vav 2 guanine nucleotide exchange factor -
VAV3 vav 3 guanine nucleotide exchange factor FLJ40431
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70

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TCR signaling icon TCR Signaling

The T cell receptor (TCR) engages with antigen presenting cells of the innate immune system. Engagement of the TCR by an MHC molecule presenting its cognate antigen along with co-stimulation activates the T cell, whereas T cell tolerance or anergy are induced when the TCR is engaged without co-stimulation or with a low affinity antigen.

Symbol Name Synonyms
AKT1 v-akt murine thymoma viral oncogene homolog 1 AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
AKT2 v-akt murine thymoma viral oncogene homolog 2 PKBB, PKBBETA, PRKBB, RAC-BETA
AKT3 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
BCL10 B-cell CLL/lymphoma 10 CARMEN, CIPER, CLAP, c-E10, mE10
CARD11 caspase recruitment domain family, member 11 BIMP3, CARMA1, MGC133069
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence C-CBL, CBL2, RNF55
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b DKFZp686J10223, DKFZp779A0729, DKFZp779F1443, FLJ36865, FLJ41152, Nbla00127, RNF56
CBLC Cas-Br-M (murine) ecotropic retroviral transforming sequence c CBL-3, CBL-SL, RNF57
CD247 CD247 molecule CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
CD28 CD28 molecule MGC138290, Tp44
CD3D CD3d molecule, delta (CD3-TCR complex) CD3-DELTA, T3D
CD3E CD3e molecule, epsilon (CD3-TCR complex) FLJ18683, T3E, TCRE
CD3G CD3g molecule, gamma (CD3-TCR complex) CD3-GAMMA, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T3G
CD4 CD4 molecule CD4mut
CD40LG CD40 ligand CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L
CD8A CD8a molecule CD8, Leu2, MAL, p32
CD8B CD8b molecule CD8B1, LYT3, Leu2, Ly3, MGC119115
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) CDC42Hs, G25K
CDK4 cyclin-dependent kinase 4 CMM3, MGC14458, PSK-J3
CHP calcium binding protein P22 SLC9A1BP
CHP2 calcineurin B homologous protein 2 -
CHUK conserved helix-loop-helix ubiquitous kinase IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
CSF2 colony stimulating factor 2 (granulocyte-macrophage) GMCSF, MGC131935, MGC138897
CTLA4 cytotoxic T-lymphocyte-associated protein 4 CD, CD152, CELIAC3, CTLA-4, GSE, ICOS, IDDM12
FOS v-fos FBJ murine osteosarcoma viral oncogene homolog AP-1, C-FOS
FYN FYN oncogene related to SRC, FGR, YES MGC45350, SLK, SYN
GRAP2 GRB2-related adaptor protein 2 GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38
GRB2 growth factor receptor-bound protein 2 ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
ICOS inducible T-cell co-stimulator AILIM, CD278, MGC39850
IFNG interferon, gamma IFG, IFI
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta FLJ40509, IKK-beta, IKK2, IKKB, MGC131801, NFKBIKB
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO
IL10 interleukin 10 CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
IL2 interleukin 2 IL-2, TCGF, lymphokine
IL4 interleukin 4 BCGF-1, BCGF1, BSF1, IL-4, MGC79402
IL5 interleukin 5 (colony-stimulating factor, eosinophil) EDF, IL-5, TRF
ITK IL2-inducible T-cell kinase EMT, LYK, MGC126257, MGC126258, PSCTK2
JUN jun oncogene AP-1, AP1, c-Jun
KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2
LAT linker for activation of T cells LAT1, pp36
LCK lymphocyte-specific protein tyrosine kinase YT16, p56lck, pp58lck
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) SLP-76, SLP76
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 DKFZp434L132, MLT, MLT1
MAP3K14 mitogen-activated protein kinase kinase kinase 14 FTDCR1B, HS, HSNIK, NIK
MAP3K8 mitogen-activated protein kinase kinase kinase 8 COT, EST, ESTF, FLJ10486, TPL2, Tpl-2, c-COT
NCK1 NCK adaptor protein 1 MGC12668, NCK, NCKalpha
NCK2 NCK adaptor protein 2 GRB4, NCKbeta
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 MGC138448, NF-ATC, NFAT2, NFATc
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 NFAT1, NFATP
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFAT4, NFATX
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 NF-ATc4, NFAT3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 DKFZp686C01211, EBP-1, KBF1, MGC54151, NF-kappa-B, NFKB-p105, NFKB-p50, p105, p50
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha IKBA, MAD-3, NFKBI
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta IKBB, TRIP9
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon IKBE
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog ALPS4, N-ras, NRAS1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 MGC130000, MGC130001, PAKalpha
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 PAK65, PAKgamma
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 CDKN1A, MRX30, MRX47, OPHN3, PAK3beta, bPAK, hPAK3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 PAK5
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 KIAA1264, MGC26232, PAK5
PDCD1 programmed cell death 1 CD279, PD1, SLEB2, hPD-1, hPD-l
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide MGC142161, MGC142163, PI3K, p110-alpha
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide DKFZp779K1237, MGC133043, PI3K, PI3KCB, PI3Kbeta, PIK3C1, p110-BETA
PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide p110D
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide PI3CG, PI3K, PI3Kgamma, PIK3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GRB1, p85, p85-ALPHA
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) P85B, p85, p85-BETA
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) DKFZp686P05226, FLJ41892, p55, p55-GAMMA
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 F730038I15Rik, FOAP-2, P101-PI3K, p101
PLCG1 phospholipase C, gamma 1 PLC-II, PLC1, PLC148, PLCgamma1
PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B
PPP3CB protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform CALNA2, CALNB
PPP3CC protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform CALNA3
PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform CALNB1, CNB, CNB1
PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform PPP3RL
PRKCQ protein kinase C, theta MGC126514, MGC141919, PRKCT, nPKC-theta
PTPN6 protein tyrosine phosphatase, non-receptor type 6 HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
PTPRC protein tyrosine phosphatase, receptor type, C B220, CD45, CD45R, GP180, LCA, LY5, T200
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) CALDAG-GEFI, CALDAG-GEFII, MGC129998, MGC129999, RASGRP, V, hRasGRP1
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) MGC131774, NFKB3, p65
RHOA ras homolog gene family, member A ARH12, ARHA, RHO12, RHOH12
SOS1 son of sevenless homolog 1 (Drosophila) GF1, GGF1, GINGF, HGF, NS4
SOS2 son of sevenless homolog 2 (Drosophila) FLJ25596
TEC tec protein tyrosine kinase MGC126760, MGC126762, PSCTK4
TNF tumor necrosis factor (TNF superfamily, member 2) DIF, TNF-alpha, TNFA, TNFSF2
TRAC T cell receptor alpha constant -
TRAJ1 T cell receptor alpha joining 1 (non-functional) -
TRAJ10 T cell receptor alpha joining 10 -
TRAJ11 T cell receptor alpha joining 11 -
TRAJ12 T cell receptor alpha joining 12 -
TRAJ13 T cell receptor alpha joining 13 -
TRAJ14 T cell receptor alpha joining 14 -
TRAJ15 T cell receptor alpha joining 15 -
TRAJ16 T cell receptor alpha joining 16 -
TRAJ17 T cell receptor alpha joining 17 -
TRAJ18 T cell receptor alpha joining 18 -
TRAJ19 T cell receptor alpha joining 19 (non-functional) -
TRAJ2 T cell receptor alpha joining 2 (non-functional) -
TRAJ20 T cell receptor alpha joining 20 -
TRAJ21 T cell receptor alpha joining 21 -
TRAJ22 T cell receptor alpha joining 22 -
TRAJ23 T cell receptor alpha joining 23 -
TRAJ24 T cell receptor alpha joining 24 -
TRAJ25 T cell receptor alpha joining 25 (non-functional) -
TRAJ26 T cell receptor alpha joining 26 -
TRAJ27 T cell receptor alpha joining 27 -
TRAJ28 T cell receptor alpha joining 28 -
TRAJ29 T cell receptor alpha joining 29 -
TRAJ3 T cell receptor alpha joining 3 -
TRAJ30 T cell receptor alpha joining 30 -
TRAJ31 T cell receptor alpha joining 31 -
TRAJ32 T cell receptor alpha joining 32 -
TRAJ33 T cell receptor alpha joining 33 -
TRAJ34 T cell receptor alpha joining 34 -
TRAJ35 T cell receptor alpha joining 35 (non-functional) -
TRAJ36 T cell receptor alpha joining 36 -
TRAJ37 T cell receptor alpha joining 37 -
TRAJ38 T cell receptor alpha joining 38 -
TRAJ39 T cell receptor alpha joining 39 -
TRAJ4 T cell receptor alpha joining 4 -
TRAJ40 T cell receptor alpha joining 40 -
TRAJ41 T cell receptor alpha joining 41 -
TRAJ42 T cell receptor alpha joining 42 -
TRAJ43 T cell receptor alpha joining 43 -
TRAJ44 T cell receptor alpha joining 44 -
TRAJ45 T cell receptor alpha joining 45 -
TRAJ46 T cell receptor alpha joining 46 -
TRAJ47 T cell receptor alpha joining 47 -
TRAJ48 T cell receptor alpha joining 48 -
TRAJ49 T cell receptor alpha joining 49 -
TRAJ5 T cell receptor alpha joining 5 -
TRAJ50 T cell receptor alpha joining 50 -
TRAJ52 T cell receptor alpha joining 52 -
TRAJ53 T cell receptor alpha joining 53 -
TRAJ54 T cell receptor alpha joining 54 -
TRAJ56 T cell receptor alpha joining 56 -
TRAJ57 T cell receptor alpha joining 57 -
TRAJ58 T cell receptor alpha joining 58 (non-functional) -
TRAJ59 T cell receptor alpha joining 59 (non-functional) -
TRAJ6 T cell receptor alpha joining 6 -
TRAJ61 T cell receptor alpha joining 61 (non-functional) -
TRAJ7 T cell receptor alpha joining 7 -
TRAJ8 T cell receptor alpha joining 8 -
TRAJ9 T cell receptor alpha joining 9 -
TRAV1-1 T cell receptor alpha variable 1-1 TCRAV1S1, TCRAV7S1, TRAV11
TRAV1-2 T cell receptor alpha variable 1-2 TCRAV1S2, TCRAV7S2, TRAV12
TRAV10 T cell receptor alpha variable 10 TCRAV10S1, TCRAV24S1
TRAV12-1 T cell receptor alpha variable 12-1 TCRAV12S1, TCRAV2S3, TRAV121
TRAV12-2 T cell receptor alpha variable 12-2 TCRAV12S2, TCRAV2S1, TRAV122
TRAV12-3 T cell receptor alpha variable 12-3 TCRAV12S3, TCRAV2S2, TRAV123
TRAV13-1 T cell receptor alpha variable 13-1 TCRAV13S1, TCRAV8S1, TRAV131
TRAV13-2 T cell receptor alpha variable 13-2 TCRAV13S2, TCRAV8S2, TRAV132
TRAV14DV4 T cell receptor alpha variable 14/delta variable 4 TCRAV6S1-hDV104S1, TRAV14/DV4, hADV14S1
TRAV16 T cell receptor alpha variable 16 TCRAV16S1, TCRAV9S1
TRAV17 T cell receptor alpha variable 17 TCRAV17S1, TCRAV3S1
TRAV18 T cell receptor alpha variable 18 TCRAV18S1
TRAV19 T cell receptor alpha variable 19 TCRAV12S1, TCRAV19S1
TRAV2 T cell receptor alpha variable 2 TCRAV11S1, TCRAV2S1
TRAV20 T cell receptor alpha variable 20 TCRAV20S1, TCRAV30S1
TRAV21 T cell receptor alpha variable 21 TCRAV21S1, TCRAV23S1
TRAV22 T cell receptor alpha variable 22 TCRAV13S1, TCRAV22S1
TRAV23DV6 T cell receptor alpha variable 23/delta variable 6 TCRAV17S1, TRAV23/DV6, hADV23S1
TRAV24 T cell receptor alpha variable 24 TCRAV18S1, TCRAV24S1
TRAV25 T cell receptor alpha variable 25 TCRAV25S1, TCRAV32S1
TRAV26-1 T cell receptor alpha variable 26-1 TCRAV26S1, TCRAV4S2, TRAV261
TRAV26-2 T cell receptor alpha variable 26-2 TCRAV26S2, TCRAV4S1, TRAV262
TRAV27 T cell receptor alpha variable 27 TCRAV10S1, TCRAV27S1
TRAV29DV5 T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) TCRAV21S1, TRAV29/DV5, hADV29S1
TRAV3 T cell receptor alpha variable 3 (gene/pseudogene) TCRAV16S1, TCRAV3S1
TRAV30 T cell receptor alpha variable 30 TCRAV29S1, TCRAV30S1
TRAV34 T cell receptor alpha variable 34 TCRAV26S1, TCRAV34S1
TRAV35 T cell receptor alpha variable 35 TCRAV25S1, TCRAV35S1
TRAV36DV7 T cell receptor alpha variable 36/delta variable 7 TCRAV28S1, TRAV36/DV7, hADV36S1
TRAV38-1 T cell receptor alpha variable 38-1 TCRAV14S2, TCRAV38S1, TRAV381
TRAV38-2DV8 T cell receptor alpha variable 38-2/delta variable 8 TCRAV14S1, TRAV382DV8, hADV38S2
TRAV39 T cell receptor alpha variable 39 TCRAV27S1, TCRAV39S1
TRAV4 T cell receptor alpha variable 4 TCRAV20S1, TCRAV4S1
TRAV40 T cell receptor alpha variable 40 TCRAV31S1, TCRAV40S1
TRAV41 T cell receptor alpha variable 41 TCRAV19S1, TCRAV41S1
TRAV5 T cell receptor alpha variable 5 TCRAV15S1, TCRAV5S1
TRAV6 T cell receptor alpha variable 6 TCRAV5S1, TCRAV6S1
TRAV7 T cell receptor alpha variable 7 TCRAV7S1
TRAV8-1 T cell receptor alpha variable 8-1 TCRAV1S1, TCRAV8S1, TRAV81
TRAV8-2 T cell receptor alpha variable 8-2 TCRAV1S5, TCRAV8S2, TRAV82
TRAV8-3 T cell receptor alpha variable 8-3 TCRAV1S4, TCRAV8S3, TRAV83
TRAV8-4 T cell receptor alpha variable 8-4 TCRAV1S2, TCRAV8S4, TRAV84
TRAV8-6 T cell receptor alpha variable 8-6 TCRAV1S3, TCRAV8S6, TRAV86
TRAV8-7 T cell receptor alpha variable 8-7 (non-functional) TCRAV8S7, TRAV87
TRAV9-1 T cell receptor alpha variable 9-1 TCRAV9S1, TRAV91
TRAV9-2 T cell receptor alpha variable 9-2 TCRAV22S1, TCRAV9S2, TRAV92
TRBC1 T cell receptor beta constant 1 BV05S1J2.2, MGC88817, TCRBC1
TRBC2 T cell receptor beta constant 2 TCRBC2
TRBD1 T cell receptor beta diversity 1 TCRBD1
TRBD2 T cell receptor beta diversity 2 TCRBD2
TRBJ1-1 T cell receptor beta joining 1-1 TCRBJ1S1, TRBJ11
TRBJ1-2 T cell receptor beta joining 1-2 TCRBJ1S2, TRBJ12
TRBJ1-3 T cell receptor beta joining 1-3 TCRBJ1S3, TRBJ13
TRBJ1-4 T cell receptor beta joining 1-4 TCRBJ1S4, TRBJ14
TRBJ1-5 T cell receptor beta joining 1-5 TCRBJ1S5, TRBJ15
TRBJ1-6 T cell receptor beta joining 1-6 TCRBJ1S6, TRBJ16
TRBJ2-1 T cell receptor beta joining 2-1 TCRBJ2S1, TRBJ21
TRBJ2-2 T cell receptor beta joining 2-2 TCRBJ2S2, TRBJ22
TRBJ2-3 T cell receptor beta joining 2-3 TCRBJ2S3, TRBJ23
TRBJ2-4 T cell receptor beta joining 2-4 TCRBJ2S4, TRBJ24
TRBJ2-5 T cell receptor beta joining 2-5 TCRBJ2S5, TRBJ25
TRBJ2-6 T cell receptor beta joining 2-6 TCRBJ2S6, TRBJ26
TRBJ2-7 T cell receptor beta joining 2-7 TCRBJ2S7, TRBJ27
TRBV10-1 T cell receptor beta variable 10-1(gene/pseudogene) TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101
TRBV10-2 T cell receptor beta variable 10-2 TCRBV10S2, TCRBV12S3, TRBV102
TRBV10-3 T cell receptor beta variable 10-3 TCRBV10S3, TCRBV12S1A1N2, TRBV103
TRBV11-1 T cell receptor beta variable 11-1 TCRBV11S1, TCRBV21S1, TRBV111
TRBV11-2 T cell receptor beta variable 11-2 TCRBV11S2, TCRBV21S3A2N2T, TRBV112
TRBV11-3 T cell receptor beta variable 11-3 TCRBV11S3, TCRBV21S2A2, TRBV113
TRBV12-3 T cell receptor beta variable 12-3 TCRBV12S3, TCRBV8S1, TRBV123
TRBV12-4 T cell receptor beta variable 12-4 TCRBV12S4, TCRBV8S2A1T, TRBV124
TRBV12-5 T cell receptor beta variable 12-5 TCRBV12S5, TCRBV8S3, TRBV125
TRBV13 T cell receptor beta variable 13 TCRBV13S1, TCRBV23S1A2T
TRBV14 T cell receptor beta variable 14 TCRBV14S1, TCRBV16S1A1N1
TRBV15 T cell receptor beta variable 15 TCRBV15S1, TCRBV24S1A3T
TRBV16 T cell receptor beta variable 16 (gene/pseudogene) TCRBV16S1, TCRBV25S1A2PT
TRBV17 T cell receptor beta variable 17 (non-functional) TCRBV17S1, TCRBV26S1P
TRBV18 T cell receptor beta variable 18 TCRBV18S1
TRBV19 T cell receptor beta variable 19 TCRBV17S1A1T, TCRBV19S1
TRBV2 T cell receptor beta variable 2 TCRBV22S1A2N1T, TCRBV2S1
TRBV20-1 T cell receptor beta variable 20-1 TCRBV20S1, TCRBV2S1, TRBV201
TRBV24-1 T cell receptor beta variable 24-1 TCRBV15S1, TCRBV24S1, TRBV241
TRBV25-1 T cell receptor beta variable 25-1 TCRBV11S1A1T, TCRBV25S1, TRBV251
TRBV27 T cell receptor beta variable 27 FLJ35984, TCRBV14S1, TCRBV27S1
TRBV28 T cell receptor beta variable 28 TCRBV28S1, TCRBV3S1
TRBV29-1 T cell receptor beta variable 29-1 TCRBV29S1, TCRBV4S1A1T, TRBV291
TRBV3-1 T cell receptor beta variable 3-1 TCRBV3S1, TCRBV9S1A1T, TRBV31
TRBV30 T cell receptor beta variable 30 (gene/pseudogene) TCRBV20S1A1N2, TCRBV30S1
TRBV4-1 T cell receptor beta variable 4-1 BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41
TRBV4-2 T cell receptor beta variable 4-2 TCRBV4S2, TCRBV7S3A2T, TRBV42
TRBV4-3 T cell receptor beta variable 4-3 TCRBV4S3, TCRBV7S2A1N4T, TRBV43
TRBV5-1 T cell receptor beta variable 5-1 TCRBV5S1, TCRBV5S1A1T, TRBV51
TRBV5-4 T cell receptor beta variable 5-4 TCRBV5S4, TCRBV5S6A3N2T, TRBV54
TRBV5-5 T cell receptor beta variable 5-5 TCRBV5S3A2T, TCRBV5S5, TRBV55
TRBV5-6 T cell receptor beta variable 5-6 TCRBV5S2, TCRBV5S6, TRBV56
TRBV5-7 T cell receptor beta variable 5-7 (non-functional) TCRBV5S7, TCRBV5S7P, TRBV57
TRBV5-8 T cell receptor beta variable 5-8 TCRBV5S4A2T, TCRBV5S8, TRBV58
TRBV6-1 T cell receptor beta variable 6-1 TCRBV13S3, TCRBV6S1, TRBV61
TRBV6-2 T cell receptor beta variable 6-2 (gene/pseudogene) TCRBV13S2A1T, TCRBV6S2, TRBV62
TRBV6-3 T cell receptor beta variable 6-3 TCRBV13S9/13S2A1T, TCRBV6S3, TRBV63
TRBV6-4 T cell receptor beta variable 6-4 TCRBV13S5, TCRBV6S4, TRBV64
TRBV6-5 T cell receptor beta variable 6-5 TCRBV13S1, TCRBV6S5, TRBV65
TRBV6-6 T cell receptor beta variable 6-6 TCRBV13S6A2T, TCRBV6S6, TRBV66
TRBV6-7 T cell receptor beta variable 6-7 (non-functional) TCRBV13S8P, TCRBV6S7, TRBV67
TRBV6-8 T cell receptor beta variable 6-8 TCRBV13S7P, TCRBV6S8, TRBV68
TRBV6-9 T cell receptor beta variable 6-9 TCRBV13S4, TCRBV6S9, TRBV69
TRBV7-2 T cell receptor beta variable 7-2 MGC117435, TCRBV6S5A1N1, TCRBV7S2, TRBV72
TRBV7-3 T cell receptor beta variable 7-3 TCRBV6S1A1N1, TCRBV7S3, TRBV73
TRBV7-4 T cell receptor beta variable 7-4 (gene/pseudogene) TCRBV6S8A2T, TCRBV7S4, TRBV74
TRBV7-6 T cell receptor beta variable 7-6 TCRBV6S3A1N1T, TCRBV7S6, TRBV76
TRBV7-7 T cell receptor beta variable 7-7 TCRBV6S6A2T, TCRBV7S7, TRBV77
TRBV7-8 T cell receptor beta variable 7-8 TCRBV6S2A1N1T, TCRBV7S8, TRBV78
TRBV7-9 T cell receptor beta variable 7-9 TCRBV6S4A1, TCRBV7S9, TRBV79
TRBV9 T cell receptor beta variable 9 TCRBV1S1A1N1, TCRBV9S1
TRDC T cell receptor delta constant -
TRDD1 T cell receptor delta diversity 1 -
TRDD2 T cell receptor delta diversity 2 -
TRDD3 T cell receptor delta diversity 3 TCRD
TRDJ1 T cell receptor delta joining 1 TCRD
TRDJ2 T cell receptor delta joining 2 -
TRDJ3 T cell receptor delta joining 3 -
TRDJ4 T cell receptor delta joining 4 -
TRDV1 T cell receptor delta variable 1 hDV101S1
TRDV2 T cell receptor delta variable 2 MGC117421, hDV102S1
TRDV3 T cell receptor delta variable 3 hDV103S1
TRGC1 T cell receptor gamma constant 1 C1, TCRGC1
TRGC2 T cell receptor gamma constant 2 TCRGC2, TRGC2(2X), TRGC2(3X)
TRGJ1 T cell receptor gamma joining 1 J1, TCRGJ1
TRGJ2 T cell receptor gamma joining 2 J2, TCRGJ2
TRGJP T cell receptor gamma joining P JP, TCRGJP
TRGJP1 T cell receptor gamma joining P1 JP1, TCRGJP1
TRGJP2 T cell receptor gamma joining P2 JP2, TCRGJP2
TRGV2 T cell receptor gamma variable 2 MGC42817, TCRGV2, VIS2
TRGV3 T cell receptor gamma variable 3 TCRGV3, V1S3
TRGV4 T cell receptor gamma variable 4 TCRGV4, V1S4
TRGV5 T cell receptor gamma variable 5 TCRGV5, V1S5
TRGV8 T cell receptor gamma variable 8 TCRGV8, V1S8
TRGV9 T cell receptor gamma variable 9 MGC47828, TCRGV9, V2
VAV1 vav 1 guanine nucleotide exchange factor VAV
VAV2 vav 2 guanine nucleotide exchange factor -
VAV3 vav 3 guanine nucleotide exchange factor FLJ40431
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70

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TGF beta icon TGFbeta

In the immune system, Tumour Growth Factor beta (TGFbeta) signaling and its downstream effector molecules, the Smad proteins, regulate the adaptive immune response through effects on numerous immune cell types including T cells and B cells. It also impacts the development and function of innate immune cells including NK cells, macrophages, dendritic cells, and granulocytes.

Symbol Name Synonyms
ACVR1B activin A receptor, type IB ACTRIB, ACVRLK4, ALK4, SKR2
ACVR1C activin A receptor, type IC ACVRLK7, ALK7
ACVR2A activin A receptor, type IIA ACTRII, ACVR2
ACVR2B activin A receptor, type IIB ACTRIIB, ActR-IIB, MGC116908
ACVRL1 activin A receptor type II-like 1 ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
AMHR2 anti-Mullerian hormone receptor, type II AMHR, MISR2, MISRII
BMP1 bone morphogenetic protein 1 FLJ44432, PCOLC, PCP, TLD, pCP-2
BMP10 bone morphogenetic protein 10 MGC126783
BMP15 bone morphogenetic protein 15 GDF9B, ODG2, POF4
BMP2 bone morphogenetic protein 2 BMP2A
BMP3 bone morphogenetic protein 3 BMP-3A
BMP4 bone morphogenetic protein 4 BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
BMP5 bone morphogenetic protein 5 MGC34244
BMP6 bone morphogenetic protein 6 VGR, VGR1
BMP7 bone morphogenetic protein 7 OP-1
BMP8A bone morphogenetic protein 8a FLJ14351, FLJ45264
BMP8B bone morphogenetic protein 8b BMP8, MGC131757, OP2
BMPR1A bone morphogenetic protein receptor, type IA 10q23del, ACVRLK3, ALK3, CD292, SKR5
BMPR1B bone morphogenetic protein receptor, type IB ALK-6, ALK6, CDw293
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK
GDF1 growth differentiation factor 1 -
GDF10 growth differentiation factor 10 BMP-3b, BMP3B
GDF11 growth differentiation factor 11 BMP-11, BMP11
GDF15 growth differentiation factor 15 GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
GDF2 growth differentiation factor 2 BMP-9, BMP9
GDF3 growth differentiation factor 3 -
GDF5 growth differentiation factor 5 BMP14, CDMP1, LAP4, OS5, SYNS2
GDF6 growth differentiation factor 6 BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1
GDF7 growth differentiation factor 7 BMP12
GDF9 growth differentiation factor 9 -
GDNF glial cell derived neurotrophic factor ATF1, ATF2, HFB1-GDNF
INHA inhibin, alpha -
INHBA inhibin, beta A EDF, FRP
INHBB inhibin, beta B MGC157939
INHBC inhibin, beta C IHBC
INHBE inhibin, beta E MGC4638
LEFTY1 left-right determination factor 1 LEFTB, LEFTYB
LEFTY2 left-right determination factor 2 EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
NODAL nodal homolog (mouse) MGC138230
TGFB1 transforming growth factor, beta 1 CED, DPD1, TGFB, TGFbeta
TGFB2 transforming growth factor, beta 2 MGC116892, TGF-beta2
TGFB3 transforming growth factor, beta 3 ARVD, FLJ16571, TGF-beta3
TGFBR1 transforming growth factor, beta receptor 1 AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
TGFBR3 transforming growth factor, beta receptor III BGCAN, betaglycan

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TGF beta icon TLR

The toll like receptors (TLR) play a key role in the innate immune system. They are found on dendritic cells and macrophages and sense conserved microbial molecules during an infection. When TLRs sense a microbial pathogen, they trigger signalling pathways that lead to the activation of an immune response.

Symbol Name Synonyms
TLR1 toll-like receptor 1 TIL, CD281, rsc786, TIL. LPRS5
TLR10 toll-like receptor 10 CD290
TLR12P toll like receptor 12, pseudogene(TLR12P) -
TLR2 toll-like receptor 2 TIL4, CD282
TLR3 toll-like receptor 3 CD283, IIAE2
TLR4 toll-like receptor 4 TOLL, CD284, TLR-4, ARMD10
TLR5 toll-like receptor 5 SLE1, TIL3, SLEB1, MELIOS
TLR6 toll-like receptor 6 CD286
TLR7 toll-like receptor 7 TLR7-like
TLR8 toll-like receptor 8 CD288
TLR9 toll-like receptor 9 CD289

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TGF beta icon TNF

The tumor necrosis factor (TNF) family of proteins are predominantly expressed by immune cells and help to regulate the immune response and inflammation. They act as cytokines when cleaved from the cell membrane and can also function as signaling proteins involved in proliferation, cell differentiation, and apoptosis.

Symbol Name Synonyms
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain CD264, DCR2, TRAILR4, TRUNDD
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b MGC29565, OCIF, OPG, TR1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A CD266, FN14, TWEAKR
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C BAFF-R, BAFFR, CD268, MGC138235
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) ATAR, HVEA, HVEM, LIGHTR, TR2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 BCM, BCMA, CD269
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 AITR, GITR, GITR-D
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 TAJ, TAJ-alpha, TRADE, TROY
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A CD120a, FPF, MGC19588, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 BM-018, DR6, MGC31965
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 ACT35, CD134, OX40, TXGP1L
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy DCR3, DJ583P15.1.1, M68, TR6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 CD30, D1S166E, Ki-1
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 4-1BB, CD137, CDw137, ILA, MGC2172
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 APO2L, Apo-2L, CD253, TL2, TRAIL
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 APO3L, DR3LG, MGC129581, MGC20669, TWEAK
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 CD258, HVEML, LIGHT, LTg, TR2
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 AITRL, GITRL, MGC138237, TL6, hGITRL
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 CD153, CD30L, CD30LG, MGC138144
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 4-1BB-L, CD137L

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Additional Resources

Plasmid Kits and Collections

Addgene Blogs

External Resouces

  • Immport: Bhattacharya S, Dunn P, Thomas CG, Smith B, Schaefer H, Chen J, Hu Z, Zalocusky KA, Shankar RD, Shen-Orr SS, Thomson E, Wiser J, Butte AJ. 2018. ImmPort, toward repurposing of open access immunological assay data for translational and clinical research. Sci Data. Feb 27;5:180015. doi: 10.1038/sdata.2018.15. PMID 29485622
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