Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.
Holiday Schedule: Addgene will be closed December 24 - January 1, 2020. For more information, see our holiday shipping schedule. If you have any questions, please contact us at [email protected].

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

viral-service-icon-v3.png Viral Service: Chemogenetics AAV


Use our chemogenetics AAV to chemically induce neuronal activity in specific cell types. See our Chemogenetics Plasmids and Chemogenetics Guide pages for more information about this field.

Receptor

  • Activating
  • Inhibitory

Promoter

Tag

  • Fusion tags
  • Non-fusion tags (IRES)

Activity

Serotype

ID Name Receptor and Activity Reporter/Tag Cre requirement Serotype(s) PI
Synapsin promoter
44361 pAAV-hSyn-DIO-hM3D(Gq)-mCherry hM3D(Gq) - Activation mCherry fusion Cre-dependent 2, 5, 8, 9, rg*, PHPeB Roth
44362 pAAV-hSyn-DIO-hM4D(Gi)-mCherry hM4D(Gi) - Inhibition mCherry fusion Cre-dependent 2, 5, 8, 9, rg*, PHPeB Roth
65417 pAAV-hSyn-dF-HA-KORD-IRES-mCitrine kappa-opioid receptor (KOR) - Inhibition IRES mCitrine Cre-dependent 8 Roth
50454 pAAV-hSyn-DIO-HA-hM3D(Gq)-IRES-mCitrine hM3D(Gq) - Activation HA fusion and IRES mCitrine Cre-dependent 8 Roth
50455 pAAV-hSyn-DIO-HA-hM4D(Gi)-IRES-mCitrine hM4D(Gi) - Inhibition HA fusion and IRES mCitrine Cre-dependent 8 Roth
50474 pAAV-hSyn-hM3D(Gq)-mCherry hM3D(Gq) - Activation mCherry fusion none 2, 5, 8, rg* Roth
50475 pAAV-hSyn-hM4D(Gi)-mCherry hM4D(Gi) - Inhibition mCherry fusion none 2, 5, 8, rg* Roth
119741 AAV SYN flex PSAM4 GlyR IRES EGFP PSAM4 GlyR - Inhibition IRES EGFP Cre-dependent 5 Sternson
121538 pAAV SYN1 HA-hM4D(Gi) hM4D(Gi) - Inhibition HA fusion none 5 Richie
121539 pAAV SYN1 HA-hM3D(Gq) hM3D(Gq) - Activation HA fusion none 5 Richie
CaMKIIa promoter
50467
New!
pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine hM4D(Gi) - Inhibition HA fusion and IRES mCitrine none 2 Roth
50476 pAAV-CaMKIIa-hM3D(Gq)-mCherry hM3D(Gq) - Activation mCherry fusion none 5, 8 Roth
50477 pAAV-CaMKIIa-hM4D(Gi)-mCherry hM4D(Gi) - Inhibition mCherry fusion none 5, 8 Roth
CD68 promoter
75033 pAAV CD68-hM4D(Gi)-mCherry hM4D(Gi) - Inhibition mCherry fusion none 1 Roth
GFAP promoter
50478 pAAV-GFAP-hM3D(Gq)-mCherry hM3D(Gq) - Activation mCherry fusion none 5 Roth
50479 pAAV-GFAP-hM4D(Gi)-mCherry hM4D(Gi) - Inhibition mCherry fusion none 5 Roth

*AAVrg = retrograde serotype, produced with the AAV retro helper plasmid from the Karpova and Schaffer labs. See the Retrograde AAV Inventory Page.

No available items found to match all requested criteria. Please consider using fewer filtering options.

Don’t See What You’re Looking For?

Please let us know what you would like to see available in viral format. Please note this does not guarantee viral service, but lets us know what viruses would be helpful to the scientific community.

Return to top