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Addgene is open for ordering and depositing; find up-to-date details here. To learn more about how we are supporting COVID-19 research and to find related plasmids, check out our COVID-19 and Coronavirus Plasmids & Resources page.

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COVID-19 and Coronavirus Plasmids & Resources

Please Note: We are automatically prioritizing orders related to ongoing coronavirus and COVID-19 research. Additionally, if you would like to deposit materials related to coronavirus or COVID-19 research, please email us at [email protected].

The global research community is moving quickly to expand the knowledge and understanding of COVID-19 and related coronaviruses. To assist with this effort Addgene will maintain this plasmid collection page, which outlines various plasmids available and those coming soon. Additionally, we have linked to collections of open-access articles, protocols, and other resource collections related to COVID-19 that may be of use to scientists.


The Coronavirus Disease-2019 (COVID-19) pandemic is caused by a novel virus strain from the Coronaviridae family called SARS-CoV-2. Scientists have been working at lightning speed to elucidate as much as they can about this novel virus. It is now known that SARS-CoV-2 entry, like that of SARS-CoV and MERS CoV, depends on binding of the viral spike (S) protein to cellular receptors. The cellular receptor for SARS-CoV-2 and SARS-CoV is hACE2, an angiotensin receptor. Another key step is the priming of the S protein by host cell proteases. The S protein of SARS-CoV-2 is primed by the serine protease TMPRSS2.

Image credit: Maya Kostman for the Innovative Genomics Institute
Single virion with all parts labeled

Addgene COVID-19 Resources

The following types of resources can be found on this page:

  • SARS-CoV-2 Plasmids: Plasmids that are available or coming soon containing SARS-CoV-2 sequences.
  • SARS-CoV Plasmids: Plasmids that are available containing SARS-CoV (SARS classic) sequences.
  • Human Targets: Plasmids containing human sequences linked to SARS-CoV-2 infection.
  • General Tools: Plasmids expressing Cas12a/Cas13a, Reverse Transcriptases, etc. that may be useful for detection assays and more.
  • Research Articles: A list of free access articles on COVID-19 research.
  • Protocols: Protocols that may be useful for COVID-19 research.


SARS-CoV-2 Plasmids