Addgene is a non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids.

Special Collections

  • Genome Engineering

    Includes CRISPRs, TALENs, and zinc fingers for targeted genome editing.

  • Fluorescent Proteins

    Find vectors for fluorescent protein tagging here.

  • Optogenetics

    Tools such as channelrhodopsins, GCaMPs, GECOs, VSFPs, and more.

  • Empty Backbones

    Plasmids for expression, knockdown and cloning.

  • Stem Cell Factors

    Transient, conditional, and stable expression of c-Myc, Klf4, Oct3/4, Nanog, Lin28, and Sox2 for ESCs and iPSCs.

  • See More Collections

    Decipher shRNA libraries, the human kinase ORF collection, and more.


  • Read All About It!

    Addgene's Fall Newsletter is here and it includes our new Plasmids 101 eBook, hot plasmids, and more.

  • Updated CRISPR Tools CRISPR-Cas9 Validated gRNAs Icon

    Check out all the Validated gRNAs available here.

  • New Fluorescent Protein Collection!

    Michael Davidson and his lab at FSU have deposited their extensive fluorescent protein collection. Browse them here.

  • Interested in Synthetic Biology?

    We've organized the SynBio plasmids and kits available, created an assembly standards guide, and more.