Addgene is a non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids.

Special Collections

  • Genome Engineering

    Includes CRISPRs, TALENs, and zinc fingers for targeted genome editing.

  • Fluorescent Proteins

    Find vectors for fluorescent protein tagging here.

  • Optogenetics

    Tools such as channelrhodopsins, GCaMPs, GECOs, VSFPs, and more.

  • Empty Backbones

    Plasmids for expression, knockdown and cloning.

  • Stem Cell Factors

    Transient, conditional, and stable expression of c-Myc, Klf4, Oct3/4, Nanog, Lin28, and Sox2 for ESCs and iPSCs.

  • See More Collections

    Decipher shRNA libraries, the human kinase ORF collection, and more.


  • New Fluorescent Protein Collection!

    Michael Davidson and his lab at FSU have deposited their extensive fluorescent protein collection. Browse them here.

  • Read All About It!

    Addgene's Summer Newsletter is here and it includes our new Synthetic Biology Guide, our most popular blog posts, and more.

  • Find the Newest CRISPR Tools CRISPR-Cas9 Cut Icon

    Empty gRNA vectors, CRISPR libraries, and more.

  • Looking for Career Advice?

    Read Addgene's blog! We've got advice from PIs on everything from choosing a research project to starting your own lab.

  • 10 Year Anniversary Addgene: 10 years of plasmid sharing

    Learn about our most popular plasmid technologies over the past 10 years. Read more.