Addgene is a non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids.

Special Collections

  • Genome Engineering

    Includes CRISPRs, TALENs, and zinc fingers for targeted genome editing.

  • Fluorescent Proteins

    Find vectors for fluorescent protein tagging here.

  • Optogenetics

    Tools such as channelrhodopsins, GCaMPs, GECOs, VSFPs, and more.

  • Empty Backbones

    Plasmids for expression, knockdown and cloning.

  • Stem Cell Factors

    Transient, conditional, and stable expression of c-Myc, Klf4, Oct3/4, Nanog, Lin28, and Sox2 for ESCs and iPSCs.

  • See More Collections

    Decipher shRNA libraries, the human kinase ORF collection, and more.


  • Addgene's Spring Newsletter

    New CRISPR resources, Plasmids 101 blog series, Hot Plasmids, and more.

  • New CRISPR Libraries Available

    Human and mouse Lentiviral CRISPR Libraries are now available.

  • Addgene Featured in Nature

    Read about our history and the role of biological resource centers in Nature.

  • 10 Year Anniversary

    Learn about our most popular plasmid technologies over the past 10 years. Read more.

  • Plasmids 101: What is a plasmid?

    Check out our new “Plasmids 101” series designed to educate all levels of scientists and plasmid lovers. Read more.