NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins.
Campbell AE, Shadle SC, Jagannathan S, Lim JW, Resnick R, Tawil R, van der Maarel SM, Tapscott SJ
Elife. 2018 Mar 13;7. pii: 31023. doi: 10.7554/eLife.31023.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 106332 | pCW57.1-MBD3L2 | All-in-one lentivector with tet-inducible MBD3L2 |
| 106352 | pZLCv2-gD4Z4-1-3xFLAG-dCas9-HA-2xNLS | CRISPR/Cas9 engineered chromatin immunoprecipitation of D4Z4 locus |
| 106353 | pZLCv2-gD4Z4-2-3xFLAG-dCas9-HA-2xNLS | CRISPR/Cas9 engineered chromatin immunoprecipitation of D4Z4 locus |
| 106354 | pZLCv2-gD4Z4-3-3xFLAG-dCas9-HA-2xNLS | CRISPR/Cas9 engineered chromatin immunoprecipitation of D4Z4 locus |
| 106355 | pZLCv2-gMYOD1-3xFLAG-dCas9-HA-2xNLS | CRISPR/Cas9 engineered chromatin immunoprecipitation of MYOD1 locus |
| 106357 | pZLCv2-3xFLAG-dCas9-HA-2xNLS | Empty backbone for CRISPR/Cas9 engineered chromatin immunoprecipitation |