4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING.
Li W, Li Y, Kang J, Jiang H, Gong W, Chen L, Wu C, Liu M, Wu X, Zhao Y, Ren J
Cell Rep. 2023 Mar 28;42(3):112145. doi: 10.1016/j.celrep.2023.112145. Epub 2023 Feb 28.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 198181 | pcmv3-IRG1-HA | Mammalian expression of HA-tagged human ACOD1 (IRG1) |
| 198182 | pcmv3-IRG1-N152S-HA | Mammalian expression of HA-tagged human ACOD1 (IRG1) N152S |
| 198183 | pcmv3-IRG1-H159Q-HA | Mammalian expression of HA-tagged human ACOD1 (IRG1) H159Q |
| 198184 | pcmv3-IRG1-L272Q-HA | Mammalian expression of HA-tagged human ACOD1 (IRG1) L272Q |
| 198185 | pcmv3-IRG1-H277Y-HA | Mammalian expression of HA-tagged human ACOD1 (IRG1) H277Y |
| 198186 | pcmv3-STING-C64S,C65S-FLAG | Mammalian expression of FLAG-tagged mouse STING1 C64S, C65S |
| 198187 | pcmv3-STING-C88S-FLAG | Mammalian expression of FLAG-tagged mouse STING1 C88S |
| 198188 | pcmv3-STING-C1471S-FLAG | Mammalian expression of FLAG-tagged mouse STING1 C1471S |